De centrale vraag is wat Nederland kan leren van de wijze waarop deze landen de rechtshandhaving en de rechtstaat in hun overzeese gebieden hebben ingericht.

The soil ecosystem consists of the largest reservoir of biodiversity on Earth.

Op 28 februari 2019 verdedigde Kabir Duggal zijn proefschrift 'Principles of Evidence in Investor-State Arbitration, Burden, Standards, Presumptions & Inferences'. Het promotieonderzoek is begeleid door promotor prof. dr. E. De Brabandere.

Promotores: H.W. Lenstra, A. Lucchini

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst

Promotor: Prof.dr. J.W.M. Frenken

This PhD-thesis analyses the relationship between the parties’ choices in the CPB Netherlands Bureau for Economic Policy Analysis’ assessments of the election manifestos and coalition agreements over the period 1986-2017, and tries to explain this relationship.

Hoe blijven we toch fit nu we meer thuiswerken?

Op 27 juni 2019 verdedigde Vid Prislan zijn proefschrift 'Domestic Courts in Investor-State Arbitration: Partners, Suspects, Competitors'. Het promotieonderzoek is begeleid door promotor prof. dr. N.J. Schrijver.

Promotor: M. Danhof, Co-promotor: E.C.M. de Lange

Anthropogenic noise has been shown to affect marine animals in various ways, this may have fitness consequences at individual and population level. This thesis aims to increase insight into the quantification of sound-induced behavioural responses that are relevant to fitness, and into factors that…

Sommige ernstige geweldsincidenten eindigen met dodelijke afloop, andere niet. Vooral vuurwapengebruik door de dader, de aan- of afwezigheid van omstanders en het gedrag van het slachtoffer blijken cruciaal voor deze uitkomst.

Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.

AI MAPS richt zich op drie thema's om de belangrijkste uitdagingen op het gebied van veiligheid aan te pakken, en benadert deze door de lens van vrijheid en sociaal welzijn.

De Tuinclub is een subvereniging van ProParte.

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

To this day, all cyclophellitol-based inhibitors and ABPs have been close analogues of their natural substrate counterparts. As a result, these probes showed high selectivity towards their target glycosidases.

Systems with local constraints is a new finding in recent researches on complex systems. The heterogeneous spatial interactions and the temporal dependencies among those numerous units make it difficult to describe by traditional statistical physics.

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich

To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.

The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.

There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.

Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.

Promotors: Prof.dr. P.J. Punt, Prof.dr. C.A.M.J.J. van den Hondel

Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska

Het ‘Leer te Durven!’ programma is een preventieve training voor kinderen met lichte angstklachten (Simon & Bögels, 2014). Het programma is speciaal ontwikkeld voor kinderen tussen de 8 en 12 jaar die zich angstig voelen of angstig gedragen, situaties vermijden, bang zijn om dingen fout te doen, schrikachtig…

In deze vuistdikke bundel vertellen meer dan honderd Nederlandse onderzoekers het wereldwijde verhaal van de Nederlandse geschiedenis

My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.

The energy system is at the heart of two of the greatest challenges of the 21st century: decreasing CO2 emissions to meet the ambitions of the Paris agreement while fulfilling the growing energy demand associated with the economic aspirations of a growing world population.

Why do black holes emit thermal radiation? And how does a closed quantum system thermalize?

With the energy transition toward a renewable energy supply and a CO2-neutral economy, electrification of the energy system is rising in importance, which leads to the challenge of long-term storage of renewable electricity.

The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.

Modeling and analysis of cyber-physical systems are still challenging. One reason is that cyber-physical systems involve many different parts (cyber or physical), of different nature (discrete or continuous), and in constant interaction via sensing and actuating.

Over the last three decades, the discovery of exoplanets has revealed the boundless variety of worlds beyond our own Solar System⁠. Majority of planetary systems contain short-period planets that are larger than Earth but smaller than Neptune⁠.

Promotor: A.P. IJzerman

Docenten in het hoger onderwijs zijn experts in wát zij doceren, maar niet noodzakelijk in hóe zij dit zouden moeten doen. Dit komt omdat zij vaak weinig tot geen training hebben gehad in het lesgeven. Daarnaast zijn zij over het algemeen meer georiënteerd op hun eigen vakgebied dan op hun rol als docent.…

Op 3 november 2021 verdedigde Lucas Noyon het proefschrift 'Strafrecht en publieke opinie'. Het promotieonderzoek is begeleid door prof.mr. J.H. Crijns en prof.dr. J.W. de Keijser.

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

Over the last decades, aviation safety has improved strongly. As a downside, airline pilots do not have as many opportunities to develop through experience the competencies that they need in critical situations.

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…

Ethiopian wolves are endangered diurnal Afroalpine rodent hunters. I investigated the interaction between wolves, rodents and human land use in Borena Sayint National Park (BSNP), Abune Yosef and Aboi Gara in Ethiopia.

Cyber agent technology en de WIV is een project dat in opdracht van Tracks Inspector, een bedrijf dat innovatieve software ontwikkelt, wordt uitgevoerd.