1,535 zoekresultaten voor “is a in africa” in de Publieke website
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When galaxy clusters collide: the impact of merger shocks on cluster gas and galaxy evolution
Promotor: Prof.dr. H.J.A. Rottgering
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Dynamic organization of bacterial chromatin by DNA bridging proteins
Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.
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Reactivity of cobalt(II)-dichalcogenide complexes: correlation between redox conversion and ligand-field strength
The redox-conversion reaction of metal-disulfide and metal-thiolate complexes are important, as they may shed light on electron-transfer reactions that often occur in Nature.
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Accelerating the Photocatalytic Water Splitting in Catalyst−Dye Complexes
As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.
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Omics data integration with genome-scale modelling of dopaminergic neuronal metabolism
Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.
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Prediction of brain target site concentrations on the basis of CSF PK: impact of mechanisms of blood-to-brain transport and within brain distribution
Promotor: M. Danhof, Co-promotor: E.C.M. de Lange
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Bioengineering and biophysics of viral hemorrhagic fever
Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…
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Women Writing Mexico (WWM)
Women Writing Mexico (WWM) is a network of women and men concerned with the human rights crisis in Mexico and more specifically, with the impact of structural forms of poverty, everyday violence, and discrimination based on gender, race, social class, and ethnicity, that particularly have an impact…
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Functions of P38 and ERK kinases in zebrafish early development
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar
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Two-Prover Bit-Commitments: Classical, Quantum and Non-Signaling
This thesis considers multi-prover commitment schemes whose security is based on restrictions on the communication between the provers.
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Periodic pulse solutions to slowly nonlinear reaction-diffusion systems
Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher
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T-CYCLE EPR: Development at 275 GHz for the study of reaction kinetics & intermediates
A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.
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Exploring future multi-messenger Galactic astronomy
For centuries astronomers studied the Universe by collecting light. Nowadays, we are living in times of great technological advancements, which allow us to explore our Universe in a new way - though gravitational wave radiation.
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Collateral Transactions and Shadow Banking
Op 13 oktober 2021 verdedigde Ross Spence het proefschrift 'Collateral Transactions and Shadow Banking'. Het promotieonderzoek is begeleid door promotoren prof.mr. M. Haentjens en prof.dr. A.M. Pacces (UvA).
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Disrupting the transcriptional machinery to combat triple-negative breast cancer
Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by limited treatment options and unfavorable clinical outcomes. Therefore, the research described in this thesis focused on the exploration of novel targeted therapies for TNBC.
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Complex Patterns in Streams
The goal of the project is the development of stream mining techniques for complex patterns such as graphs. We will try to extend the existing state-of-the-art techniques into two, orthogonal directions: on the one hand, the mining of more complex patterns in streams, such as sequential patterns and…
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Design and development of conformational inhibitors and activity-based probes for retaining glycosidases
Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.
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Exploring the magnetic, turbulent Milky Way through radio waves
Promotor: Prof.dr. H. J. A. Röttgering, Co-Promotor: M. Haverkorn
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Noonan and LEOPARD syndrome in zebrafish: molecular mechanisms and cardiac development
Promotor: Prof.dr. J. den Hertog
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Mechanical and genetics basis of cellularization and serosal window closure in Tribolium castaneum
The applications of studying the early development of insects range from agriculture to material science.
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Invariant manifolds and applications for functional differential equations of mixed type
Promotor: S.M. Verduyn Lunel
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Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgery
Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst
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Software developments in automated structure solution and crystallographic studies of the Sso10a2 and human C1 inhibitor protein
Promotor: Prof.dr. J.P. Abrahams, Co-Promotor: N.S. Pannu
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Deepening the uncertainty dimension of environmental Life Cycle Assessment: addressing choice, future and interpretation uncertainties.
LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.
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Data-Driven Risk Assessment in Infrastructure Networks
Leiden University and the Ministry of Infrastructure and Water Management are involved in a collaboration in the form of a research project titled 'Data-Driven Risk Assessment in Infrastructure Networks'
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High throughput microscopy of mechanism-based reporters in druginduced liver injury
Promotor: B. van de Water
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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Chemical reactivity of O2, CO and CO2 on Cu surfaces
Despite the history of studies on methanol formation from CO2, the dominant elementary reaction steps that constitute the chemical mechanism for this catalyzed process are not determined.
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Corporate venture management in SMEs: evidence from the German IT consulting industry
Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)
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Systems diagnosis of chronic diseases, explored by metabolomics and ultra-weak photon emission
Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang
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The evolution and plasticity of life histories upon variation in nutrition: on aging focused integrative approach
Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)
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Microneedle-mediated vaccine delivery
Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot
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Abiotic depletion in LCIA
Possible improvements for the assessment of abiotic depletion in LCA.
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Cryo Electron Tomography Studies On Bacterial Chemosensory Arrays
Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.
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Fate, accumulation and impact of metallic nanomaterials in the terrestrial environment
The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.
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SAPPAO - Optimizing the flight times of airplanes using data science
Met het SAPPAO-project willen we de voorspelling van geplande vluchten nauwkeuriger en betrouwbaarder maken. De volledige naam van het project is ‘A Systems Approach towards Data Mining and Prediction in Airlines Operations’.
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Nanofluidic tools for bioanalysis : the large advantages of the nano-scale
Promotor: Prof.dr. T. Hankemeier, Prof.dr. J.C.T. Eijkel (Twente University)
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Focal-plane wavefront sensors for direct exoplanet imaging: Theory, simulations and on-sky demonstrations
One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…
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Discovery of novel Antibiotics from Actinomycetes by Integrated Metabolomics & Genomics Approaches
Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi
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Controlling growth and morphogenesis of the industrial enzyme producer Streptomyces lividans
Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom
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Engineering of antigen-saving dissolving microneedles for intradermal vaccine delivery
The intradermal administration route is attractive for vaccine delivery, because of the highly populated antigen-presenting cells in the skin. However, the skin’s main physical barrier, the stratum corneum, prevents vaccines from entering the skin.
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Risks to Health and the Environment Related to the Use of Lead in Products
The aim of this project was to estimate emissions from lead products-in-use for the past, the present and the future and assess the development of toxicological risks associated with these products.
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Electroextraction approaches for preconcentration of metabolites
In this thesis, we developed new ways to use a technique called electroextraction (EE) to extract charged molecules from one liquid into another using an electric field.
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GLOBOX
GLOBOX is a spatially differentiated multimedia fate, exposure and effect model. It is used for the calculation of spatially differentiated LCA characterisation factors on a global scale.
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PhD Position: Computational Modeling of Auger Capture Rates
Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)
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Archeologie-alumnus Valerio Gentile wint W.A. van Es-prijs
Valerio Gentile kreeg de prijs tijdens de Reuvensdagen uitgereikt voor zijn masterscriptie 'Martiality in Practice'. Hij is de eerste internationale student die de prestigieuze prijs wint. De W.A. van Es-prijs wordt jaarlijks toegekend door de Rijksdienst voor het Cultureel Erfgoed.
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'Solidarity under strain - A legal, criminological and economic analysis' - Leiden Interdisciplinary Migration Seminar
Wednesday 16 November 2016, 12.30-14.00
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Ann Skelton eerste bekleder wisselleerstoel Enforcement of Children's Rights
De nieuwe wisselleerstoel is ingesteld om gerenommeerde wetenschappers de kans te bieden om in Leiden onderwijs en onderzoek te doen naar internationale kinderrechten en tegelijkertijd de opgedane kinderrechtenkennis wereldwijd goed te ontsluiten.
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Collegecolumn: Annetje Ottow over Brussel, Afrika en maatschappelijke impact
In het kader van vernieuwen en verbinden – het thema van ons nieuwe strategisch plan – bracht ik afgelopen week een bezoek aan Brussel. Het is belangrijk de Universiteit Leiden een gezicht in Brussel te geven en te laten zien welke expertise we in huis hebben, bijvoorbeeld op het gebied van Afrika.
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Biomedicus Taniawati Supali ontvangt Bosscha Medaille
Tijdens de opening van de Leiden-Delft-Erasmus BRIN Academy op 31 oktober is de Bosscha Medaille uitgereikt aan Taniawati Supali, biomedicus aan de Universiteit van Indonesië. Supali krijgt de medaille voor haar excellente bijdrage aan de wetenschap en haar werkwijze die zich kenmerkt door samenwerking,…