This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.

Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.

Recht is - net als de religie - een vorm van kunst, aldus de auteur.

Cognitive enhancement is het gebruik van elke methode of techniek met als doel het verbeteren van cognitieve prestaties.

LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.

In september is de tweede herziene druk verschenen van Leo Lucassen en Jan Lucassen, Winnaars en verliezers. Een nuchtere balans van vijf eeuwen immigratie (Bert Bakker/Prometheus). Deze editie bevat een nawoord waarin de auteurs ingaan op de relatie tussen de aanslagen van Anders Breivik in Noorwegen…

During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.

Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.

Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.

Op 24 september 2020 verdedigde Bernardo Ribeiro de Almeida zijn proefschrift 'Building land tenure systems: the political, legal, and institutional struggles of Timor-Leste'. Het promotieonderzoek is begeleid door promotor prof.dr. A.W. Bedner.

The research presented in this thesis makes use of small molecules (as H2 , D2 and O2 ) on well-defined single crystal surfaces (flat Pt(111), flat Cu(211) and curved Pt(111)) to elucidate the role of surface structure and degrees of freedom in the reactant in specific surface reactions.

Promotor: F.S. de Boer, Co-promotor: M.M. Bonsangue

Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.

Wat is de maatschappelijke impact (sociale betekenis) van vrouwenvoetbal in Nederland?

This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…

Fase 2A van het Gorlaeus Gebouw wordt, net als fase 1, duurzaam gebouwd.

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot

Detecting planets during their formation stages is crucial for understanding the history and diversity of fully developed planetary systems like our own. However, observing young planets directly is challenging because they are often deeply embedded within their host protoplanetary discs, rich in gas…

Op 27 mei 2021 verdedigde Hirad Abtahi zijn proefschrift 'Adjudicating Attacks Targeting Culture'. Het promotieonderzoek is begeleid door promotor prof.dr. C. Stahn.

Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.

Wetland plants are distinguished from plants of other terrestrial ecosystems by their adaptations to specific habitat stresses, including waterlogged and flooding and the subsequent abundance of phytotoxic compounds.

The majority (80%) of e-waste generated globally are recycled informally in developing countries.

This thesis focuses on the social dimensions of crane and wetland conservation in rural landscapes in Kenya, Uganda and Zimbabwe.

Promotor: A.P. IJzerman

This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.

A management strategy has been developed for field margins to reduce pesticide drift to non-target areas and to promote biodiversity on arable land. To this end, 3 and 6 m wide strips along the edges of winter wheat, sugar beet and potato crops have been left unsprayed with herbicides and insecticides…

Promotor: Prof.dr. H. J. A. Röttgering, Co-Promotor: M. Haverkorn

Promotores: J. Kok, M. Chaudron (Chalmers University)

Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.

Na een voor Frankrijk desastreus verlopen oorlog tegen Pruisen brak in 1871 een opstand uit die de geschiedenis zou ingaan als de Parijse Commune. Op 18 maart van dat jaar bezetten opstandige Parijzenaars de stad. 72 dagen later werden zij in bloedige barricadegevechten verpletterend verslagen. Vele…

Promotor: J.W.M. Frenken Co-Promotores: I.M.N. Groot; L.B.F. Juurlink

Cholesterol influences many pathways, including serving as precursor for adrenal steroidogenesis. Imbalance of cholesterol levels has been implicated in several diseases including cardiovascular diseases and its underlying pathology, atherosclerosis.

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…

In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.

Learning from small data sets in machine learning is a crucial challenge, especially when dealing with data imbalances and anomaly detection. This thesis delves into the challenges and methodologies of learning from small datasets in machine learning, with a particular focus on addressing data imbalances…

Op 21 januari 2021 verdedigde Fachrizal Afandi zijn proefschrift 'Maintaining Order: Public Prosecutors in Post-Authoritarian Countries, the case of Indonesia'. Het promotieonderzoek is begeleid door promotoren prof.dr. A.W. Bedner en prof.dr. J.H. Crijns.

Het Instituut Pedagogische Wetenschappen van de Universiteit Leiden doet onderzoek naar de ontwikkeling van jonge kinderen met selectief mutisme

Op 29 januari 2019 verdedigde Robbert van Eijk proefschrift 'Web Privacy Measurement in Real-Time Bidding Systems, A Graph- Based Approach to RTB system classification'. Het promotieonderzoek is begeleid door promotor prof. dr. H.J. van den Herik.

Op 11 juni 2020 verdedigde Sabine Witting haar proefschrift 'Child Sexual Abuse in the Digital Era: Rethinking Legal Frameworks and Transnational Law Enforcement Collaboration'. Het promotieonderzoek is begeleid door promotoren prof.mr. J.J. Sloth-Nielsen en prof.dr.mr. S. van der Hof.

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.

On a structural level, the properties featured by a majority of mechanical metamaterials can be ascribed to the finite number of soft internal degrees-of freedom allowing for low-energy deformations.

Giles Scott-Smith, 'Interdoc. Een geheim netwerk in de Koude Oorlog' (Amsterdam 2012) Uitgeverij Boom.

Lange tijd werd de Nederlandse politiek gedomineerd door drie ideologische stromingen: de christendemocratie, de sociaaldemocratie en het liberalisme. Inmiddels zijn deze hoofdstromen smaller geworden en zijn er ter linker- en rechterzijde diverse nieuwe politieke stromen en stroompjes ontstaan. In…

Op 19 februari 2020 verdedigde Richard Jiang zijn proefschrift '‘Greening’ the WTO Ban on China’s Export Duties'. Het promotieonderzoek is begeleid door promotor prof.dr. M.C.E.J. Bronckers.

Niet-gekozen vertegenwoordigers zoals huisartsen, ouderenorganisaties en kerken vormen een belangrijk kanaal om in gemeenten de stem te laten horen van burgers die gebruik maken van jeugdzorg, maatschappelijke ondersteuning en toeleiding naar werk. Dit concluderen de onderzoekers Hester van de Bovenkamp…

The role of material production as a driver of environmental impacts is increasing, which calls for a better understanding of global material flows. This thesis explores the role of in-use stocks of products, buildings and infrastructure as a key driver of global material demand and discusses the implications…

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.