1,587 zoekresultaten voor “fundamental study” in de Publieke website
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Surveying young stars with Gaia: Orion and the Solar neighbourhood
OB associations are loose groups of young, massive stars. They constitute the last stage of the massive starformation process, and the context in which new stars are formed.
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Hierarchical Systems
The thesis addresses the long-term dynamical evolution of hierarchical multiple systems.
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Studentenleven in Den Haag
Voor studenten kan studeren in Den Haag het verschil maken. Den Haag draagt met trots de titel ‘internationale stad van vrede en recht’. Den Haag biedt volop kansen en is een geweldige studentenstad.
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Topics in the arithmetic of del Pezzo and K3 surfaces
Promotores: P. Stevenhagen, L. van Geemen (Università degli studi di Milano), Co-Supervisor: Ronald M. van Luijk
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Photothermal circular dichroism studies of single nanoparticles
In this work, we investigate the minute circular dichroism effects of single nanoparticles.To this aim, we apply photothermal imaging with a polarization-modulated heating beam.
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Substances from Cradle to Grave
Materials balances have been used in the recent past for the analysis of substance oriented environmental problems and the formulation of measures for environmental policy. In this study an integrated tool, based on the materials balance principle, has been developed for the analysis of both environmental…
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CD8+ T-cells in atherosclerosis: mechanistic studies revealing a protective role in the plaque microenvironment
Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.
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Libya Since the 2011 Revolution: Troubles, Causes, and Future
Professor Dirk Vandewalle is een internationaal veelgevraagde en gerenommeerde Libië-expert. In deze lezing gaat hij in op twee essentiële vragen over de huidige situatie in Libië. Hoe komt het dat het Libische politieke systeem zo fragiel geworden is? En hoeveel hoop is er nog dat Libië als eenheid…
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Cyclophellitol analogues for profiling of exo- and endo-glycosidases
To this day, all cyclophellitol-based inhibitors and ABPs have been close analogues of their natural substrate counterparts. As a result, these probes showed high selectivity towards their target glycosidases.
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Leiden University College The Hague
Leiden University College The Hague (LUC) biedt een 3-jarige bacheloropleiding aan waarin je je focust op Global Challenges; grote uitdagingen waar de mensheid mee te maken heeft: Vrede & Rechtvaardigheid, Diversiteit, Duurzaamheid en Welvaart. Je hebt ruimte om de opleiding zo in te richten als je…
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Quality-driven multi-objective optimization of software architecture design: method, tool, and application
Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich
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Inverse Jacobian and related topics for certain superelliptic curves
To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
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Boosting the host immune system to fight tuberculosis
New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.
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Enlightening the Primordial Dark Ages
This thesis is dedicated to the exploration of the primordial dark ages: unknown physics during the earliest stages of the Universe’s expansion that have not yet been directly probed by observations. Cosmic inflation is a burst of exponential expansion of space after the “Big Bang”.
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De verzamelwoede van Martinus van Marum (1750-1837) en de ouderdom van de aarde
Promotor: F.J. van Lunteren, E. Jorin
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The use of computational toxicology in hazard assessment of engineered nanomaterials
Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…
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Simulating the birth environment of circumstellar discs
Circumstellar discs are the reservoirs of gas and dust that surround young stars and have the potential to become planetary systems.
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Dynamics and regulation of the oxidative stress response upon chemical exposure
The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…
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Dynamic real-time substrate feed optimization of anaerobic co-digestion plants
Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)
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Multiscale mathematical biology of cell-extracellular matrix interactions during morphogenesis
During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.
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Thrips resistance in Gladiolus: an eco-metabolomic approach
Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.
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Environmental and health impact of informal e-waste recycling
The majority (80%) of e-waste generated globally are recycled informally in developing countries.
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Vaccination and Targeted Therapy Using Liposomes; Opportunities for Treatment of Atherosclerosis and Cancer
This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.
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Exploring the magnetic, turbulent Milky Way through radio waves
Promotor: Prof.dr. H. J. A. Röttgering, Co-Promotor: M. Haverkorn
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Child Sexual Abuse in the Digital Era: Rethinking Legal Frameworks and Transnational Law Enforcement Collaboration
Op 11 juni 2020 verdedigde Sabine Witting haar proefschrift 'Child Sexual Abuse in the Digital Era: Rethinking Legal Frameworks and Transnational Law Enforcement Collaboration'. Het promotieonderzoek is begeleid door promotoren prof.mr. J.J. Sloth-Nielsen en prof.dr.mr. S. van der Hof.
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Interdoc: Geheim netwerk in de Koude Oorlog
Giles Scott-Smith, 'Interdoc. Een geheim netwerk in de Koude Oorlog' (Amsterdam 2012) Uitgeverij Boom.
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Spatial populations with seed-bank
In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…
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Extremely shy and genetically close
Investigating neurobiological endophenotypes of Social Anxiety Disorder
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Effect of Nanoparticles on Microbial Catabolism and Community Structure using Biolog techniques
1. To what extent do metallic NPs added to soil extractions change the activity, abundance, or community composition of microbes? 2. How do the effects of metallic NPs on soil microbes differ from the effects of the ions shedding from corresponding NPs?
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Evenementen & Activiteiten
Het Leiden Leadership Centre verbindt wetenschap en praktijk door evenementen over publiek leiderschap te organiseren – zoals Leiden Leadership Lunches, webinars, (internationale) conferenties en de Leiden Leadership Podcast.
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Laborinth II : denken als experiment : 472 'meditaties' over de noodzaak van het creatief denken en experimenteren in het uitvoeren van complexe
Dit proefschrift onderzoekt de noodzaak van het creatief denken en experimenteren in het uitvoeren van complexe muziek in de late twintigste- en vroege eenentwintigste eeuw.
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Exploring future multi-messenger Galactic astronomy
For centuries astronomers studied the Universe by collecting light. Nowadays, we are living in times of great technological advancements, which allow us to explore our Universe in a new way - though gravitational wave radiation.
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Synthetic, Physical and Computational Chemistry of Propeller-shaped Polycyclic Aromatic Hydrocarbons
This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…
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Studentenleven
Leiden is een echte studentenstad. Meld je aan voor een studievereniging of studentenvereniging om van jouw studietijd een onvergetelijke tijd te maken!
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A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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Leiden University College The Hague
Leiden University College The Hague (LUC) biedt een 3-jarige bacheloropleiding aan waarin je je focust op Global Challenges; grote uitdagingen waar de mensheid mee te maken heeft: Vrede & Rechtvaardigheid, Diversiteit, Duurzaamheid en Welvaart. Je hebt ruimte om de opleiding zo in te richten als je…
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Re-integratieondersteuning van interne en externe professionals tijdens detentie
Op 11 oktober verdedigde Amanda Pasma het proefschrift 'Re-integratieondersteuning van interne en externe professionals tijdens detentie'. Het promotieonderzoek is begeleid door Paul Nieuwbeerta, Hanneke Palmen en Esther van Ginneken.
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Measuring gold molecular gas across cosmic time
Tracing the evolution of the molecular gas content in galaxies is critical for a complete understanding of galaxy formation and evolution, as it provides the direct fuel for star formation. Studies of high-redshift (z>1) molecular gas reservoirs, most commonly traced by carbon monoxide (CO), have seen…
- Summer School: "Manuscript Studies: Codicology and Digital Techniques" (5 ECTS)
- Onderzoeksoutput
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Combining classic and novel tools in the study of Historical Collections of Chinese Materia Medica in the Netherlands
Promotie
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Engineered 3D-Vessels-on-Chip to study effects of dynamic fluid flow on human induced pluripotent stem cell derived-endothelial cells
Promotie
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Introduction to coaching
Participants in this course will learn to support student teachers and new colleagues in their professional development as teachers, with particular emphasis on the context of bilingual or international education, as in the ICLON World Teachers Programme (WTP).
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Master Classes Hugh Kennedy (Leiden)
In October and December 2021, Al-Babtain Visiting Professor Hugh Kennedy will teach six masterclasses at Leiden University on the idea of a “Greater Mesopotamia” and its fundamental importance in understanding the economy and geopolitics of the early Islamic world, from 650 to 1050 CE.
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Afrika heroverwogen
Wie Westerse media volgt, denkt al snel aan 'Afrika' als het herkomstoord van wanhopige migranten, continent van honger en ziektes, broedplaats voor internationaal terrorisme. Wie een breder beeld wil hebben, kan terecht bij de Leidse Afrikanisten. Juist door hun nauwe banden met Afrikaanse partners…
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Jerfi Uzman spreekt bij conferentie over populisme en mensenrechten
Jerfi Uzman, universitair docent bij de afdeling staats- en bestuursrecht, was op 17 januari een van de sprekers op de conferentie Fundamental rights and the relational self: overcoming the limitations of an individualistic focus in human rights law? De conferentie was georganiseerd door het Leidse…
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Data Science
Het verzamelen en interpreteren van grote hoeveelheden data is niet meer weg te denken uit de maatschappij en de wetenschap. De Universiteit Leiden is een kennis- en expertisecentrum van data science dat de nadruk legt op interdisciplinaire samenwerking en innovatie.
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Evenement: Duitsland na de verkiezingen
Vijf vragen over het evenement ‘Duitsland na de verkiezingen: gevolgen voor het buitenlands beleid en de Europese veiligheid’, beantwoord door een van de deskundigen, Joachim Koops. Kom langs op de Spaanse Trappen in Wijnhaven op vrijdag 15 oktober of doe online mee (link onderaan).
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The Skandapurāṇa Project
Uniting an international consortium of scholars, the Skandapurāṇa Project comprises a team of researchers working in fields across the Humanities. We are creating a critical edition of a foundational work of purāṇic literature and, in doing so, tracing the dynamics of a textual tradition to better understand…