Op 10 november 2021 verdedigde Carmel van Niekerk-Jacobs het proefschrift 'Realising the right to reproduce with assistance in South Africa'. Het promotieonderzoek is begeleid door prof.dr. J.J. Sloth-Nielsen en prof.dr. T. Liefaard.

Behavioral and neural mechanisms underlying risky decision-making in adolescents

Op donderdag 12 januari 2017 verdedigde Ellen Raaijmakers haar proefschrift ‘The Subjectively Experienced Severity of Imprisonment: Determinants and Consequences’. De promotors zijn prof. dr. P. Nieuwbeerta en prof. dr. J.W. de Keijser.

Theoretisch fysicus Carlo Beenakker kwam een paar jaar geleden de Majorana-deeltjes op het spoor en inspireerde Leo Kouwenhoven van de TU Delft om ze te creëren in een supergeleidende nanostructuur. In 2012 lukte dit inderdaad, en dat was wereldnieuws. Maar er is nog veel werk nodig om meerdere Majorana-qubits…

Het Leiden University Centre for Linguistics (LUCL) heeft een lange traditie in onderzoek naar de talen van de wereld en beschikt over unieke taalkundige expertise. Bij het LUCL helpen we bij het ontwikkelen van interdisciplinaire benaderingen door de interactie tussen datagestuurd en theorie gestuurd…

Promotor: Thomas Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto

Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn

Producing green energy has become the main goal in our society in the search of reducing or eliminating the carbon emission from fossil fuels.

Several single-stranded RNA viruses make use of Xrn1-resistant RNAs in their 3’ untranslated regions of their genome RNAs in order to increase their pathogenicity.

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf

A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.

Een touwtje uit de deur is het symbool voor de gezellige Nederlandse volksbuurt van vroeger. Dat gold ook voor de Schilderswijk in Den Haag. Maar de wijk heeft tegelijk al bijna een eeuw de reputatie van een beruchte achterbuurt. Mythe of werkelijkheid? En wat klopt er van het idee dat het karakter…

Low-mass main-sequence stars like our Sun are continuous sources of outflowing hot magnetised plasma. In the case of the Sun, this is known as the solar wind, whereas for other stars they are called stellar winds.

Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.

Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae

In the first part of this thesis we study the geometry of folding patterns.

Although nanoparticles are extensively used in various applications like consumer products and have most probably entered the environment, little is known about the effects of these particles on living organisms.

Promotor: E. Bouwman, Co-Promotor: S. Bonnet

Promotor: Prof.dr. A. Doelman, Co-promotor: V. Rottschäfer

In this thesis we have discussed several parameters that affect the electrochemical conversion of enviromentaly harmful molecules such as nitrates and carbon dioxide to more valuable and less deleterious compounds, in order to cast light onto the mechanism of the reaction to achieve an efficient and…

Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.

In this thesis, we show how MRFM can usefully contribute to the field of condensed-matter.

Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…

Supervisor: P.J.J. Hooykaas

This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.

Promotor: C.J. ten Cate, Co-promotor: H.W. Slabbekoorn

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh

Promotor: J. A. Bouwstra

Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh

In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

This thesis studied in depth the energy use and CO2 emissions of the industrial sector in China.

Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)

In this thesis, we describe the latest advances in SQUID-detected Magnetic Resonance Force Microscopy (MRFM).

This thesis discusses the physical and chemical processes than influence the composition of forming planets.

Promotor: R. Cramer

Promotor: Prof.dr. J.N. Kok, Co-Promotor: W.A. Kosters

One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

Promotor: W.T. de Groot

Songbirds as vocal learners learn their songs and song preference from social tutors⁠. Tutor choice for both song and preference learning are important to characterize for understanding individual learning performance and cultural transmission of song⁠.

Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.

Promotor: Prof.dr. H.J.A. Rottgering

Promotor: Prof.dr. S. Portegies Zwart

The different kinds of cultural perspectives on health and disease of the participants are related to their knowledge, beliefs, values and practices manifested in various forms of lifestyle in Indonesia. The cultural diversity of the population is also related to differences in health behaviour.