2,341 zoekresultaten voor “either that en culture” in de Publieke website
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Differences that make all the difference. Gender, migration and vulnerability (migration to the Netherlands 1945-2005)
Het voorgestelde project evalueert hoe de kwetsbaarheid van migrantenmannen en -vrouwen werd geconstrueerd in politieke, publieke en mediadiscoursen, en hoe verschillen in de geconstrueerde kwetsbaarheid van invloed waren op de beslissing om te migreren, het migratieproces en het daaropvolgende vest…
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Phenotypic screening with 3D cell-based assays
Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.
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Microvasculature in Microfluidics: matching complexity with compatibility
In vitro disease models play a fundamental role in drug research. They enable the systemic identification and validation of disease mechanisms and the discovery of possible drug targets. However, more than often, drug candidates that are identified in vitro fail in the later clinical stages of drug…
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Strategy Dynamics
In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.
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ACPA onderzoeksproject gehonoreerd voor NWO’s Smart Culture
Eén van de gehonoreerde projecten is Bridging art, design and technology through Critical Making van onze hoogleraar Prof. dr. Janneke Wesseling en dr. Florian Cramer (Willem de Kooning Academy).
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Ineke Sluiter: ‘Cancel culture is het negatieve broertje van woke’
Ineke Sluiter, hoogleraar Griekse taal en literatuur, was als voorzitter van de KNAW de keynote speaker van de Diversiteit & Inclusiviteit week aan de TU Delft. Het journalistieke platform Delta van de universiteit interviewde haar over cancel culture en woke zijn.
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Phylogenetic ecology of octocoral - gastropod associations
Promotor: E. Gittenberger, Co-promotores: L.P. van Ofwegen; B.W. Hoeksema
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Cultures of Victimology: landelijke bijeenkomst over slachtofferschap
Op 24 september 2021 kwam een groep academici en professionals op de Oude Sterrewacht bijeen om te praten over cultuur, victimologie, slachtofferschap, en hoe we dit moeten invullen.
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Better Predictions when Models are Wrong or Underspecified
Promotor: P.D. Grünwald
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Robust rules for prediction and description.
In this work, we attempt to answer the question:
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Applying data mining in telecommunications
This thesis applies data mining in commercial settings in the telecommunications industry.
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Steady-State Analysis of Large Scale Systems
Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma
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Céline Zaepffel
Faculteit der Geesteswetenschappen
c.v.zaepffel@hum.leidenuniv.nl | +31 71 527 2050
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De Koreaanse golf
De onstuitbare opmars van de N.V. Zuid-Korea
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A chemical biology approach for targeting of ligand-drug conjugates
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot
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Novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).
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Proteins in harmony: Tuning selectivity in early drug discovery
This thesis describes the importance of being able to control the selectivity of potential drug candidates.
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Exploring and exploiting the mechanism of mycelial pellet formation by Streptomyces
Promotor: G.P. van Wezel
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Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink
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Strategies for braiding and ground state preparation in digital quantum hardware
With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.
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On the amount of sieving in factorization methods
Promotoren: R. Tijdeman, A.K. Lenstra, Co-promotor: H.J.J. te Riele
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Sensing Transport
Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.
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Neutrinos From the Milky Way
Promotor: Prof.dr. M. de Jong
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Affinity-based profiling of the adenosine receptors
The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.
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Autumn School in Medieval Languages and Culture 2021
In close collaboration with the Center for Medieval Studies (Fordham), Centre for Medieval literature (Odense and York) and Centre for Medieval Studies (York), the University of Ghent organizes an Autumn School for PhD- and MA-students in Medieval Studies (18-22 October 2021). It will be organized in…
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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Tentoonstelling Books that made History
Van Galileo Galilei tot Albert Einstein, van Anna Maria van Schurman tot Anton de Kom: het is slechts een greep uit 25 auteurs die met hun boeken en ideeën een buitengewone invloed hebben gehad op de wereld, soms zelf tot nu. De Universitaire Bibliotheken Leiden en het Rijksmuseum van Oudheden organiseren…
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Environmental and metabolomic study of antibiotic production by actinomycetes
Promotor: Prof.dr. G.P. van Wezel
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
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Advanced in vitro models for studying drug induced toxicity
Promotor: B.van de Water, Co-promotor: L.S.Price
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Assembling anisotropic colloidal building blocks
This PhD-thesis presents a study on micron-sized particles, so-called colloids. By controlling the chemical and physical properties of these particles, such as the interparticle interaction and the particles’ shape, colloids can act as building blocks that self-assembly into larger structures.
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Redox Interconversion between Metal Thiolate and Disulfide Compounds
In the last decade, the redox interconversion between metal thiolate and disulfide compounds has been extensively investigated for copper, but not for other transition metal ions.
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Small-molecule inhibitors of bacterial metallo-β-lactamases
The main focus of the thesis is the discovery and development of novel inhibitors of bacterial metallo-β-lactamases (MBLs).
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Spatial populations with seed-bank
In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…
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Potential interference of fungal endophytes in Vanilla planifolia on vanilla flavor compounds biosynthesis
Natural vanilla flavor is one of the most important in the world. However, the cost of this flavor is expensive. Production of this flavor by alternative methods, could reduce the cost.
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Understanding the role of mycorrhizas in global carbon cycle processes
How the global distribution of vegetation stands dominated by arbuscular and ectomycorrhizal plants relate to principle aspects of belowground carbon accumulation processes?
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Insights into microtubule catastrophes: the effect of end-binding proteins and force
For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.
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Geslaagde feestelijke opening Books that made History
Het was weer gezellig druk in het Rijksmuseum van Oudenheden! Op 22 juni is de zomertentoonstelling ‘Books that made History’ van Universitaire Bibliotheken Leiden (UBL) en het Rijksmuseum van Oudheden (RMO) geopend. In de tentoonstelling zijn 25 Leidse boeken uit de collecties van de UBL te zien die…
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'Culture, Dispute Resolution and the Modernised Family' conference 6-8 juli Londen, UK
In juli zal een aantal onderzoekers van de Afdeling Jeugdrecht een paper presenteren op de 'Culture, Dispute Resolution and the Modernised Family' conference in Londen, georganiseerd door het International Centre for family law, policy and practice te Londen.
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Basic Program 2024-2025
The basic program comprises a total of twelve courses organized by the Research School, that have been purpose-developed for training and support of PhD students and Research MA students who specialize in Medieval Studies (history, art history, and literary history, in particular).
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Rebekah Tromblé
Students Practicing Citizen Journalism
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Scholieren maken via Frankenstein kennis met opleiding English Language and Culture
Proefstuderen kan alleen offline op locatie? Nee hoor! Bij onze faculteit zijn we eind 2019 gestart met het project Online Proefstuderen en Verplichte Matching, en daarvan is nu de eerste module Online Proefstuderen gereed, al in gebruik en draait zelfstandig. Deze Online Experience English Language…
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Multiscale mathematical biology of cell-extracellular matrix interactions during morphogenesis
During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.
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Controlling growth and morphogenesis of the industrial enzyme producer Streptomyces lividans
Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom
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Data-driven donation strategies: understanding and predicting blood donor deferral
The research in this dissertation aims to optimise blood donation processes in the framework of the Dutch national blood bank Sanquin. The primary health risk for blood donors is iron deficiency, which is evaluated based on donors' hemoglobin and ferritin levels.
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The gendered micropolitics of hiding and disclosing: assessing the spread and stagnation of information on two new EMTCT policies in a Malawian
Announcement of a new publication by Janneke Verheijen, lecturer at the Institute of Cultural Anthropology and Development Sociology.
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Exposure and health Assessment of Persistent Organic Pollutants (POPs) at e-waste recycling site among workers in the informal sector in Nigeria
Do e-waste workers display enhanced effects of adverse health effects due to informal e-waste processing in Nigeria? Is there a difference between the health outcomes of the exposed and the control groups? Are there difference in health effects within and between job groups (collectors, dismantlers,…
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Role of non-homologous end-joining in T-DNA integration in Arabidopsis thaliana
Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater
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Systems pharmacology of the endocannabinoid system
In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).
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Cyclophellitol analogues for profiling of exo- and endo-glycosidases
To this day, all cyclophellitol-based inhibitors and ABPs have been close analogues of their natural substrate counterparts. As a result, these probes showed high selectivity towards their target glycosidases.