Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans

Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.

Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…

Prof.dr. Niels Schiller is experimenteel taalwetenschapper. Hij houdt zich bezig met verwerkingsprocessen van taal in de hersenen en werkt nu aan een videobril voor doven en slechthorenden.

Mechanical interactions between cells and their environment play an important role in many biological processes.

What is the effect of light at night on plant phenology and physiology, and how does this affect plant interactions with other species?

SHINE-VR is een korte interventie in Virtual Reality (VR) die wordt toegevoegd aan een reguliere traumabehandeling (TF-CBT). We onderzoeken de effectiviteit ervan met een experimenteel ontwerp waarbij naar individuele gevallen wordt gekeken. Dit doen we specifiek met jongvolwassenen die seksueel misbruik…

Speciaal voor een experiment van Universiteit Leiden zijn bestuurskundigen en waterschapsambtenaren samengekomen in een laboratorium.

Neanderthalers konden op grote schaal vuur maken met behulp van pyriet en hun vuistbijlen. Ze konden dus zelf beslissen wanneer zij vuur wilden en waren niet afhankelijk van natuurbranden, zoals eerder gedacht werd. Archeoloog Andrew Sorensen ontdekte het eerste materiële bewijs hiervoor. Publicatie…

Promotor: M. Ubbink, Co-promotor: G. Siegal

Promotor: A.P.IJzerman Co-promotor: A. Bender

In this thesis, we have used numerical approaches to study the effects of translational symmetry breaking on strange metallic systems as realised by the holographic duality⁠.

In this thesis, we consider various (electro)chemical phenomena at surfaces and nanoparticles and their underlying atomistic processes, which we studied using first-principles methods such as density functional theory.

In this thesis we study quantum transport phenomena on the nanometer scale, in two classes of materials: topological insulators with induced superconductivity and graphene superlattices.

The emergence of complex diseases resulting from abnormal cell-cell signaling and the spread of infectious diseases caused by pathogens are significant threats to humanity. Unraveling the dynamic mechanisms underlying cell-cell signaling and infectious disease spreading is crucial for effective disease…

Promotor: E.R. Eliel, Co-Promotor: M.J.A. de Dood

In dit interdisciplinaire onderzoeksprogramma werken onderzoekers uit vijf verschillende disciplines met elkaar samen. Zij stellen zich hieronder (in het Engels) aan u voor.

Wiskunde en Natuurwetenschappen

Promotie

In this project innovative technology for photovoltaics cells is developed and analysis of ecological and health related risks are explicitly accounted for.

Promotor: K.E. Schalm, Co-promotor: S.S. Lee

Promotor: M.T.M. Koper, Co-promotors: A.I. Yanson, L.B.F. Juurlink

Promotor: Prof.dr. M. Danhof

This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.

Promotor: Prof.dr. E. Eliel, Co-Promotor: M.J.A. de Dood

Tin electrodeposition applications have rapidly evolved in the past 25 years.

Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…

Empirical Legal Studies in Leiden focust op het bouwen van een interdisciplinaire gemeenschap van rechtsgeleerden en sociale wetenschappers die samen juridische vraagstukken onderzoeken op het snijpunt van recht en gedrag, waarbij diverse soorten methoden worden gebruikt.

It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.

Een experimentele analse van de impact van liberale normen op steun voor of afwijzing van oorlogsvoering onder een groep mensen die zijn gesocialiseerd in een democratie (Nederland) en een groep die altijd heeft geleefd in een autocratie (China) toont aan dat het liberale gehalte in de democratische…

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

Organic amendments applied to agricultural fields can partially offset our carbon emissions to the atmosphere and improve the resilience of agriculture to the effects of climate change. Driving these benefits, however, are complex and poorly understood interactions between organic amendment properties,…

In the first part of this thesis we study the geometry of folding patterns.

In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.

Promotor: Thomas Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto

This thesis describes the role of pollution, specifically neonicotinoid insecticides, as an actor of the ongoing biodiversity decline.

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

Promotores: J. Jonkers, K.E. de Visser

Promotores: J.A.van Veen, P.L.G.Klinkhamer. Co-promotor: E.E.Kuramae

Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats

Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.

In most applications, electrocatalysts exhibit a large surface area to volume ratio, for example using nanoparticles.

Promotor: Roeland M.H. Merks

The application of nanomaterials in industrial processes and consumer products provides many societal benefits, but can also lead to the release of nanomaterials into the environment. The work in this dissertation aims to provide insights into the potential environmental impacts that may follow from…

Promotor: Prof.dr. P.G.L. Klinkhamer, Co-Promotor: T.J. de Jong

In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…

This thesis combines field and laboratory studies to address some of the most pressing questions in the field of microplastic research.

Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.