Hydrocarbonylation of alkenes with carboxylic acids in synthesis of carboxylic acid anhydrides is relatively less explored. We herein present a study and optimization of a palladium-catalyzed hydrocarbonylation reaction of alkenes using carboxylic acids as the nucleophile, by which acid anhydrides can…

De Leiden Slavery Studies Association (LSSA) is toegewijd aan het bevorderen van een beter begrip van slavernij en post-slavernij in elke periode en elk geografisch gebied.

Promotor: Ronald Cramer, Co-promotor: Serge Fehr

Innovation plays an essential role in firms' competitiveness and long-term success. It varies from different types, ranging from run-of-the-mill innovation that brings incremental changes to existing technologies to radical innovation that breaks from existing trajectories.

Promotores: Prof.dr. M. Franx, Prof.dr. P.G. van Dokkum (Yale University)

Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…

The class-imbalance problem is a challenging classification task and is frequently encountered in real-world applications. Various techniques have been developed to improve the imbalanced classification performance theoretically and practically.

The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.

Almost three years after receiving her honorary doctorate, Dr Graça Machel returned to Leiden University. Over the course of two days she spoke with students, researchers, and other interested persons, about human rights – particularly those of women and children – in a world in which these are continually…

Security is key to survival for any living organism: life is full of perils and threats, both physically, environmentally, and societally. Security challenges such as terrorism, natural disasters, and cybercrime rank among the most pressing issues of our time, affecting the security and safety of millions…

Studievoorlichting

Studievoorlichting

In this thesis, we consider various (electro)chemical phenomena at surfaces and nanoparticles and their underlying atomistic processes, which we studied using first-principles methods such as density functional theory.

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg

Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.

Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.

Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

This initiative is intended to support generative research collaborations between and among scholars located in different geographical regions who wish to pursue focused, joint projects in any area of the study of religion.

What Determines Perceptions of Bias toward the International Criminal Court? Evidence from Kenya. In dit artikel, gepubliceerd in op de website SAGE Journals in het Journal of Conflict Resolution, onderzoeken de auteurs Geoff Dancy, Yvonne Marie Dutton, Tessa Alleblas, Eamon Aloyo de houding ten opzichte…

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame

In this thesis, we have studied cell images from two types of cells, including pollen grains and the immune cells, neutrophils. These images are captured using a bright field microscope and a confocal microscope.

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

In this course, you will explore the organs involved in our food digestion and discover the common causes of abdominal and pelvic pain. The latest graphics and animations will give you new insights and understandings of this part of the body.

Het Instituut Biologie Leiden (IBL) opende vandaag haar deuren voor onder andere de Leidse burgemeester, Henri Lenferink. Samen met decaan van de faculteit Jasper Knoester en directeur bij de provincie Zuid-Holland Ton Jonker kreeg hij uitleg over de verschillende onderzoeken van het instituut en de…

Sobral

Lezing

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…

Promotor: J.S. Kaastra Co-promotor: E. Constantini

Een avondvullend programma in de Universiteitsbibliotheek en Middle Eastern Library in Leiden voor iedereen die iets heeft met het Midden-Oosten; van Tadjikistan tot de Mahreb en van Istanbul tot Sanaa. Bekijk de oudste boeken en kleitabletten uit de collectie en luister naar de meest fascinerende verhalen…

Dit artikel gaat in op de onderzoekskloof door te onderzoeken hoe deze instanties hun personeel zo kunnen inzetten dat ze maximale prestaties leveren met het personeel dat ze hebben.

Om de klimaatcrisis het hoofd te bieden, kan een bepaalde nederigheid van de mens ten aanzien van de natuur van groot belang zijn. Tegelijkertijd kan nederigheid ook politieke overheersing in de hand werken. Hoe kunnen mensen zich op een bescheidener manier tot de natuur verhouden zonder hun vrijheid…

This study seeks to analyse how job stress could be the result of performing administrative tasks

Dit artikel levert een bijdrage aan een groeiend aantal onderzoeken naar radicalisering. Het richt zich specifiek op het onderscheid tussen individuen die radicalisering en daardoor betrokken raken bij terroristisch geweld en individuen die radicaliseren maar niet betrokken raken bij geweld.

Jaroslaw Kantorowicz and Rok Spruk onderzoeken de bijdrage van institutionele hervormingen aan economische groei.

Onder welke omstandigheden beperken paramilitaire groepen hun gebruik van politiek geweld? Dit artikel onderzoekt het gebruik hiervan door de PIRA.

Ramesh Ganohariti onderzoekt de juridische identiteit in drie post-Sovjet aspirant-lidstaten en schetst in dit artikel vier veelvoorkomende scenario's.

A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…

Op 30 september 2021 verdedigde Babette van Hazebroek haar proefschrift 'Understanding delinquent development from childhood into early adulthood in early onset offenders'. Het promotieonderzoek is begeleid door promotoren prof.dr. J.W. de Keijser en prof. dr. A. Popma (VUMC).

Van Soledad Acosta de Samper en Albalucía Angel tot Hazel Robinson Abrahams en Amalialú Posso Figueroa. Tijdens het symposium & de workshop 'Experience and Voice: Library of Colombian Women Writers’ staan de boeken van Colombiaanse schrijfsters uit verschillende historische periodes centraal. De bijeenkomst…

The studies described in this thesis deal with glycosidases, in particular alpha-galactosidases.

The thesis describes experimental steps towards reduction of friction on the macroscopic scale by scenarios of thermo- and superlubricity well-known on the nanoscale.

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

The origin and evolution of galaxies are closely linked to many different physical phenomena.

Religion and ethnicity are inextricably linked in discourse within and about Central Asia. One common narrative suggests that as a result of differences between historically sedentary and nomadic populations, ethnic Tajiks and Uzbeks are naturally more religious and more likely to radicalise than their…

The thesis explores how interstellar chemistry evolves as a function of time and changing physical architectures during the formation of stars.

De auteurs presenteren een benadering voor het achterhalen van de voorkeuren van de bevolking voor gebruik in de optionele wegingstap in de Levenscyclusanalyse (LCA).

Promotie