This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…

In this thesis population pharmacokinetic and physiologically-based pharmacokinetic (PBPK) approaches were applied to investigate the influence of glomerular filtration (GF) and active tubular secretion (ATS) on renal clearance in children.

Veel handgeschreven en geïllustreerde archieven bevatten een schat aan informatie, maar worden weinig bestudeerd vanwege hun complexe en door computers moeilijk te ontcijferen inhoud. Het doel van dit project is een digitale omgeving te ontwikkelen die hier een oplossing voor biedt, en die de heterogene…

Promotie

Promotie

Today, knowledge is the most crucial element to stimulate organizational competitiveness and economic development.

Software development is a complex process. It is important that software products become stable and maintainable assets.

One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.

Nanodiscs are small, disc-shaped structures designed to mimic biological cell membranes, composed of a lipid bilayer stabilized by scaffold proteins. Membrane proteins play crucial roles in essential processes such as nutrient and waste transport, molecular recognition, and cell signalling, making them…

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

Promotor: Prof.dr. J.N. Kok, Co-promotor: F.J. Verbeek

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

Sinoloog Florian Schneider ontving de LUS onderwijsprijs en mag zich dit collegejaar de beste docent van de Universiteit Leiden noemen. Schneider oogstte veel lof met zijn vernieuwende, op role-playing gebaseerde onderwijsmethoden.

Eduard Fosch-Villaronga, Hadassah Drukarch en Bart Custers van eLaw - Centrum voor Recht en Digitale Technologie, onderzoeken met Pranav Khanna , eLaw alumnus, de invloed van automatisering op de interactie tussen mens en robot en verantwoordelijkheid bij chirurgische innovatie.

Sensatieverhalen vertellen, voordelen overdrijven en risico's onderschatten: ergens een 'hype' over creëren klinkt niet als iets waar een verantwoordelijke wetenschapper zich aan zou wagen. Of kunnen we een hype ook op een 'goede manier' inzetten? Wat kunnen we bereiken door discussies over de quantumtoekomst…

Joachim Koops, Professor of Security Studies and Scientific Director of Leiden University’s Institute of Security and Global Affairs (ISGA) has been awarded a ‘Jean Monnet Chair’ with a focus on ‘The European Union’s Role in Security and Global Affairs’ (EURISGA).

The new Executive Board of the Institute of Psychology became effective on 1 February 2022. Scientific director Andrea Evers tells us where she gets her energy from.

Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.

Anneleen van der Meer bespreekt het vermeende gebruik van chemische wapens door Rusland in Oekraïne in The Conversation.

Van 2 tot 5 september 2015 is Leiden het toneel van een van de grootste linguïstische congressen ter wereld: de Societas Linguistica Europaea (SLE) Annual Meeting 2015. Hoe heeft Leiden zo'n prominente positie binnen de Taalkunde gekregen? Een gesprek met taalwetenschapper Arie Verhagen.

Human vocal communication and music perception represent advanced cognitive skills, seemingly innate and universal. These faculties encompass a range of perceptual and cognitive abilities. Cross-species research sheds light on the origins of musicality by investigating whether these traits are shared…

Promotor: H.J.M. de Groot

Nauwkeurig emoties van anderen herkennen is een essentiële sociale vaardigheid, die relevant is voor het omgaan met de sociale wereld vanaf de kindertijd. Het vermogen van kinderen om dit te doen is een mijlpaal in hun sociaal-emotionele ontwikkeling en wordt geassocieerd met een aantal belangrijke…

Mechanical interactions between cells and their environment play an important role in many biological processes.

Donderdag 16 april jl. verwelkomde Campus Den Haag een belangrijke gast. De Italiaanse Federica Mogherini, Hoge Vertegenwoordiger van de Europese Commissie op het gebied van Buitenlandse Zaken en Veiligheidsbeleid bezocht Den Haag.

This thesis focuses on the role of chemokine receptors CXCR3 and CCR2 in the inflammatory process and infection control using the zebrafish model.

Op 10 november 2021 verdedigde Carmel van Niekerk-Jacobs het proefschrift 'Realising the right to reproduce with assistance in South Africa'. Het promotieonderzoek is begeleid door prof.dr. J.J. Sloth-Nielsen en prof.dr. T. Liefaard.

The research of the Applied Mathematics cluster is concerned with such diverse topics as dynamical systems, representation theory, differential equations and pattern recognition.

The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…

Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

Promotor: Prof.dr. W.J.G.M. Peijnenburg

The role of material production as a driver of environmental impacts is increasing, which calls for a better understanding of global material flows. This thesis explores the role of in-use stocks of products, buildings and infrastructure as a key driver of global material demand and discusses the implications…

The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.

Integrins play an essential role in multicellular life by connecting cells to the extracellular matrix.

Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang

Subproject of the ERC project 'Challenging the Liberal World Order from Within: The Invisible History of the United Nations and the Global South'.

Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

In this thesis, time-lapse fluorescent microscopy plays a pivotal role in investigating functional materials within living cells as well as the migratory behaviour of neural progenitor cells.

In this thesis, we focus on novel proteins/mechanisms that regulate integrin-adhesion mediated mechano-transduction.

This study attempts to understand how indigenous community institutions pose an important role in sustainable community-based development, including the integration between local culture and development.

Promotor: J.M. van den Broek Co-promotor: M.C. de Vries

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

Op 23 februari 2022 verdedigde Cale Davis het proefschrift 'Prosecutorial Discretion in International Criminal Justice'. Het promotieonderzoek is begeleid door prof.dr. C. Stahn en dr. J.C. Powderly.

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.

Op 1 april 2020 verdedigde Marc Broekema zijn proefschrift 'Cognitive Bias in the Judgment of Business Valuations and Valuators'. Het promotieonderzoek is begeleid door promotor prof. dr. J.I. van der Rest.