Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.

Promotor: Prof.dr. W.J.G.M. Peijnenburg

Fungal infections pose a significant threat to individuals with compromised immune systems and despite advancements in diagnosis and treatment, they continue to jeopardize patient’s health.

A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.

Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…

1) Assess the trends in supply and production status of these critical minerals and mineral products worldwide and Europe’s dependence including on intermediate products such as permanent magnets, RE based super alloys, batteries, polishing compounds, phosphors, catalysts etc. 2) Trace the entire value…

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.

Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.

The thesis describes terrestrial field trials aimed to detect side-effects of pesticides within the framework of pesticide registration procedures. Field trials were developed using vascular plants Brassica napus and Poa annua, caterpillars Pieris brassicae and effects on decomposition were studied…

Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…

Van Galileo Galilei tot Albert Einstein, van Anna Maria van Schurman tot Anton de Kom: het is slechts een greep uit 25 auteurs die met hun boeken en ideeën een buitengewone invloed hebben gehad op de wereld, soms zelf tot nu. De Universitaire Bibliotheken Leiden en het Rijksmuseum van Oudheden organiseren…

A management strategy has been developed for field margins to reduce pesticide drift to non-target areas and to promote biodiversity on arable land. To this end, 3 and 6 m wide strips along the edges of winter wheat, sugar beet and potato crops have been left unsprayed with herbicides and insecticides…

Accumulation of metals in economy and environment and its associated risks, within the Netherlands and the EU.

This thesis investigates the contribution of quantum computers to machine learning, a field called Quantum Machine Learning. Quantum Machine Learning promises innovative perspectives and methods for solving complex problems in machine learning, leveraging the unique capabilities of quantum computers…

The aim is to discover where differently shaped metal nanoparticles distributes in Danio rerio, linking the distribution with genomic responses and so come up with a Mode of Action.

Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.

The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.

Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.

Het was weer gezellig druk in het Rijksmuseum van Oudenheden! Op 22 juni is de zomertentoonstelling ‘Books that made History’ van Universitaire Bibliotheken Leiden (UBL) en het Rijksmuseum van Oudheden (RMO) geopend. In de tentoonstelling zijn 25 Leidse boeken uit de collecties van de UBL te zien die…

In dit interdisciplinaire onderzoeksprogramma werken onderzoekers uit vijf verschillende disciplines met elkaar samen. Zij stellen zich hieronder (in het Engels) aan u voor.

A neurocognitive investigation of the development of social performance monitoring in youth growing up in stressful versus non-stressful environments

In this project innovative technology for photovoltaics cells is developed and analysis of ecological and health related risks are explicitly accounted for.

How does the management of Elephant Marsh Fishery in Malawi relate to wider contexts of policies, theories and regions? And how can the current management system be adapted to achieve long-term sustainability of the fishery?

In times of hardships or crisis, local people know how to deal with it using their resourcefulness. Although efforts are sometimes made by the government to help them, they are fully aware that community support is at least equally important.

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri

Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…

Pauline Aarten, universitair docent bij ISGA, en Vincent van der Vlies, research fellow bij ISGA, werden geïnterviewd door Nieuw-Volendam over hun recente onderzoek naar de gemeenschappelijke impact van nationale rampen.

A critical look at the impact assessment modelling of metals in Life Cycle Impact Assessment and improvement options.

In June 2024, the University of Groningen organizes a summer school, titled "Things that Matter". The Summer School explores challenges in digitizing source materials, questioning distinctions between physical and digital copies. It delves into the impact of virtual collections and criteria for digitization,…

In de serie tafelgesprekken ‘Van kluis naar kussen’ krijgt de kijker een blik achter de schermen van de Bijzondere Collecties. In deze speciale uitzending staat de zomertentoonstelling 'Books that made History' van de Universitaire Bibliotheken Leiden en het Rijksmuseum van Oudheden centraal. In de…

Describe and identify what dosimetry parameters are of importance to interpret dose-response relationships (eg., mortality, sub-lethal, growth or reproduction inhabitation, DNA damage and reactive oxygen species, etc. ) for metal-based nanoparticles? How to develop quantitative models that enable to…

GLOBOX is a spatially differentiated multimedia fate, exposure and effect model. It is used for the calculation of spatially differentiated LCA characterisation factors on a global scale.

The research in this dissertation aims to optimise blood donation processes in the framework of the Dutch national blood bank Sanquin. The primary health risk for blood donors is iron deficiency, which is evaluated based on donors' hemoglobin and ferritin levels.

The project

This thesis is based on five papers on several topics.

Discover the unique Vital Interests course in the BSc Security Studies programme, featuring an inspiring session on climate diplomacy with Dutch UNFCCC negotiators.

Promotie

Promotie

Technology can drive peace and justice. Innovative solutions increasingly make use of new types of data, mobile technologies and social media. Big or small (data), high-tech or low-tech: the challenge is to maximise the benefits while minimising the risks that come with the so-called data revolution…

Van maandag 10 tot woensdag 12 juni 2019 vertegenwoordigden Jeroen Wolbers, Wout Broekema en Sanneke Kuipers het Institute of Security and Global Affairs (ISGA) op de vierde editie van de Noord-Europese Conferentie over Nood- en Rampenonderzoek (NEEDS).

Artikel: “The paradox of being on the glass cliff: why do women accept risky leadership positions?”

Onze promovenda Maral Darouei heeft in samenwerking met haar dagelijkse begeleider Helen Pluut een artikel gepubliceerd in het tijdschrift Career Development International (5-year IF = 2.704). Het paper is getiteld “The paradox of being on the glass cliff: Why do women accept risky leadership positions”.…

Studievoorlichting

Promotie