Promotor: C. W. J. Beenakker, Yu. V. Nazarov, Co-promotor: J. Tworzydlo

Promotores: H.A. Udo De Haes, P.M. Brakefield

Promotor: F.P. Israel, Co-Promoter: R. Meijerink

Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)

Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.

Promotor: Prof.dr. M. Danhof

The four possible segments A, T, C and G that link together to form DNA molecules, and with their ordering encode genetic information, are not only different in name, but also in their physical and chemical properties.

Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).

Taxonomy as a science has accumulated data and knowledge for more than 250 years.

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.

Promotor: K.E. Schalm, Co-promotor: S.S. Lee

Promotores: Prof.dr. J. Aarts, Prof.dr. J.M. van Ruitenbeek

Promotor: A. Achúcarro, Co-promotor: A. Boyarsky

This work is dedicated to interpreting in cohomological terms the special values of zeta functions of arithmetic schemes.

The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.

Trigonostemon Blume is a plant genus in the family Euphorbiaceae comprising 59 species.

Promotor: A. Achúcarro Co-promotor: A. Boyarsky

This ecological community has long been known to affect host biology, and their diverse roles have been further clarified in recent years following numerous studies of animal:microbiota interactions in diverse systems.

Promotor: Prof.dr. A.G.G.M. Tielens

Promotor: Prof.dr. E. Eliel, Co-Promotor: M.J.A. de Dood

This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.

This dissertation is an experimental study of laser-generated, atmospheric pressure, transient toroidal helium plasmas.

Promotor: Prof. dr. Arnold Tukker & Prof. dr. René Kemp (Maastricht University)

In het hoger onderwijs zijn open leermaterialen beschikbaar die iedereen mag gebruiken, maar ze worden niet zo veel gebruikt.

Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.

Promotor: Prof.dr. M. Ubbink

The Vallesian, 11.1-9 Ma, was a special time in the Vallès-Penedes basin near Barcelona, where a biodiversity hotspot existed. Europe had a subtropical climate, with rhinos, forest giraffes, lions, hyenas, flying squirrels and primates.

There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…

By training with virtual opponents known as computer generated forces (CGFs), trainee fighter pilots can build the experience necessary for air combat operations, at a fraction of the cost of training with real aircraft.

Cathodic corrosion is a relatively unknown phenomenon that can severely etch metallic electrodes at cathodic (negative) potentials.

Promotor: Prof.dr. C.W.J. Beenakker

This thesis is about augmented reality (AR). AR is commonly considered a technology that integrates virtual images into a user’s view of the real world.

Promotor: E.F. Smets, Co-promotor: J. Geml

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

We explored the Universe using weak gravitational lensing, a phenomenon that occurs when light from distant galaxies is bent by the gravitational fields of closer cosmic objects, much like how a lens distorts light.

In summary, the collective results described in this thesis show that nanoparticulate vaccines can be delivered intradermally by coated and hollow microneedles and evoke antigen-specific immune responses.

Promotor: Prof.dr. J. Kuiper

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

For many system in statistical physics the microcanonical and canonical ensemble are equivalent in the thermodynamic limit, but not for all.

Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri

Membrane fusion is a vital process in living organisms and is mediated by zipper-like proteins.

The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier

The availability of indicators based on social media has opened the possibility to track the online interactions between social media users and scholarly entities.

Promotor: J. N. Kok, Co-promotor: A. J. Knobbe

Supramolecular polymers are class of materials that are formed by non-covalent interactions such as hydrogen bonding, π-π interactions, electrostatic interactions and the hydrophobic effect.

Tin electrodeposition applications have rapidly evolved in the past 25 years.