1,497 zoekresultaten voor “her been deel te” in de Publieke website
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Systems pharmacokinetic models to the prediction of local CNS drug concentrations in human
Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.
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Automated de novo metabolite identification with mass spectrometry and cheminformatics
Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier
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The optimization and scale-up of the electrochemical reduction of CO₂ to formate
Carbon dioxide capture and utilization technologies are necessary to create a truly circular economy. The electrochemical reduction of carbon dioxide to formate is an appealing carbon utilization method as it can be performed at room temperature and pressure, it only requires two electrons, and it has…
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The heart of oxygenic photosynthesis illuminated
Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia
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Towards circular and energy-efficient management of building stock
Material circularity and energy efficiency are highly relevant and intertwined issues for the transition towards a carbon-neutral and circular built environment. In the Netherlands, the building sector has been rendered a priority towards a circular and low-carbon society.
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Periodic pulse solutions to slowly nonlinear reaction-diffusion systems
Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher
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Mitochondria in chemical-induced toxicity
Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…
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Cold gas in distant galaxies
The formation and evolution of galaxies is fundamentally driven by the formation of new stars out of cold gas.
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Evolutionary diversification of coral-dwelling gall crabs (Cryptochiridae)
Promotor: Prof.dr. E Gittenberger, Co-Promotores: C.H.J.M. Fransen, B.W. Hoeksema
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The music of language: exploring grammar, prosody and rhythm perception in zebra finches and budgerigars
Promotor: C.J. ten Cate
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Gauge theory and nematic order : the rich landscape of orientational phase transition
Promotor: J. Zaanen
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Biomimetic Copper Catalysts for the Electrochemical Oxygen Reduction Reaction
Human civilization consumes a huge amount of fossil fuels, which has resulted in an atmospheric CO2 level which has not been higher in over 800 millennia.
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The Miliuseae revisited: phylogenetic, taxonomic, and palynological studies in a major clade of Annonaceae
Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou
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Unravelling cell fate decisions through single cell methods and mathematical models
Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.
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The hunt for frozen organic molecules in space
Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.
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Giant unilamellar vesicles: An efficient membrane biophysical tool and its application in drug delivery studies
Promotor: A. Kros
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Stochastic and Deterministic Algorithms for Continuous Black-Box Optimization
Continuous optimization is never easy: the exact solution is always a luxury demand and the theory of it is not always analytical and elegant.
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Principal algebraic actions of the discrete Heisenberg group
Promotor: Prof.dr. W.T.F. den Hollander
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Visualization of Vitamin A Metabolism
Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.
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Pattern mining for label ranking
Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
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Discovery and exploitation of the transcriptional regulatory system of pectinases in Aspergillus niger
Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.
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Probing molecular layers with low-energy electrons
Molecular materials have been a subject of interest in fundamental research and applications for decades, and have been studied as bulk crystals, (thin) films and as individual molecules, due to the large variety in their properties. This dissertation explores pentacene crystals near the two-dimensional…
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Machine learning-based NO2 estimation from seagoing ships using TROPOMI/S5P satellite data
The marine shipping industry is one of the strongest emitters of nitrogen oxides (NOx), a pollutant detrimental to ecology and human health. Over the last 20 years, the pollution produced by power plants, the industry sector, and cars has been decreasing.
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Trading Responsibility: navigating national burdens in a globalized world
International trade has played a major role in defining the modern global economy. Trade, however, entangles the environmental pressures of economic sectors, giving the illusion of environmental improvements, while the opposite may be occurring.
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Contact
Hier vindt u de contactgegevens van de onderzoekers
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Researching Extremists and Terrorists: Reflections on Interviewing Hard-to-Reach Populations
In deze publicatie verkennen Sarah Louise Carthy en Bart Schuurman de realiteit van het benaderen en interviewen van moeilijk bereikbare bevolkingsgroepen.
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Contact
Heb je nog vragen over het Citizen Science Lab, ben je op zoek naar Citizen Science projecten om aan deel te nemen of wil je zelf een project opzetten en kan je hier hulp bij gebruiken? Neem gerust contact met ons op!
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Onderwijs voor vluchtelingen
De Universiteit Leiden ondersteunt vluchtelingstudenten door onderwijs toegankelijk te maken, obstakels op de weg naar academisch succes weg te nemen en contact met medestudenten en medewerkers te stimuleren. Dit maakt deel uit van ons streven naar een inclusieve universiteit.
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Exploring Means to Facilitate Software Debugging
In this thesis, several aspects of software debugging from automated crash reproduction to bug report analysis and use of contracts have been studied.
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Deep Hanging Out in the Age of the Digital; Contemporary Ways of Doing Online and Offline Ethnography
A brief review essay on some of the work that has been recently published in the emergent field of digital ethnography.
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Moeten techreuzen verplicht data delen?
Grote techbedrijven, zoals Google, Facebook en Apple, moeten verplicht hun data delen met nieuwkomers en concurrenten. Hiervoor pleiten wetenschappers en onderzoeksbureau TNO in een hoorzitting in Tweede Kamer. Tom Ottervanger verwacht dat het heel lastig gaat worden om dit te verplichten.
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Hendrik Casimir Prize 2016 voor Andrea Peña en Jorrit Hortensius
Op de LION/Sterrewacht nieuwjaarsborrel heeft prof. Tjerk Oosterkamp de 2016 Hendrik Casimir Prize uitgereikt aan natuurkundestudenten Andrea Peña (Leiden) en Jorrit Hortensius (Delft). The Casimir Research School deelt jaarlijks de Hendrik Casimir Prize uit aan de beste masterstudenten in (technische)…
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A culture medium based approach to optimize the stratum corneum barrier of human skin equivalents
uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.
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Leiden Jewish Studies Association
Since its beginnings, Leiden University has been home to scholars with a broad and diverse expertise in the histories, languages, literatures and material cultures relevant to the study of Jews and Judaism from antiquity to modern times.
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Ingrid Leijten neemt deel aan eerste Europese ‘Constitutional Law Schmooze’ in Milaan
Al decennialang worden in de Verenigde Staten ‘Schmoozes’ georganiseerd. Deze kleinschalige bijeenkomsten bieden de mogelijkheid om op informele wijze over belangwekkende thema’s te praten. Op 12 en 13 oktober vond in Milaan de eerste Europese Schmooze plaats, met als thema ‘Economic Inequality as a…
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Rescue of Business in Insolvency Law
The ultimate aim of this project (initiated by the European Law Institute) is to design a framework that will enable the further development of coherent and functional rules for business rescue in Europe.
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Private lessons for guitar and ukelele | English spoken
Kunst en vrije tijd, Kunst en vrije tijd
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Partners
Hieronder vindt u de organisaties waarmee het TRIXY Expertisecentrum samenwerkt.
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Masterclasses
Jaarlijks organiseert het Alumnibureau van de Universiteit Leiden een aantal masterclasses. Deze masterclasses zijn exclusief toegankelijk voor Leidse alumni.
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Inspiratie
Ben je van plan deel te nemen aan het Max Havelaar Toesprakentoernooi en wil je je goed voorbereiden, inlezen en inspiratie opdoen?
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Deelname
Om Virtual Reality in te kunnen zetten om kinderen te helpen die iets ergs hebben meegemaakt, is het heel belangrijk om te weten wat kinderen van VR vinden. Om hier achter te komen, hebben we een virtuele wereld gemaakt.
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Over elegante deeltjes en nanometers
Hij heeft wel een antwoord op de vraag wat het kleinste deeltje is. Carlo Beenakker, hoogleraar Theoretische natuurkunde aan de Universiteit Leiden: ‘Dat is een puntdeeltje. Zo’n deeltje is altijd nul. Elektronen zijn puntdeeltjes; ze zijn zo klein dat je ze niet kapot kunt slaan.’ Maar: Beenakker geeft…
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Towards High Performance and Efficient Brain Computer Interface Character Speller: Convolutional Neural Network based Methods
A P300-based Brain Computer Interface character speller, also known as P300 speller, has been an important communication pathway, under extensive research, for people who lose motor ability, such as patients with Amyotrophic Lateral Sclerosis or spinal-cord injury because a P300 speller allows human-beings…
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Probing new physics in the laboratory and in space
The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles.
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Revealing the nature of new low-frequency radio source populations
It has now been well established that shocks and turbulent motions in the intra-cluster medium (ICM) generated through cluster mergers can produce large-scale synchrotron emission.
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The Demographics of Protoplanetary Disks: from Lupus to Orion
The work presented in this thesis is based on ALMA surveys of protoplanetary disks in three star-forming regions: Lupus, OMC-2, and NGC 2024.
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Inhibitors and probes targeting mannanases
This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…
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Ab initio molecular dynamics calculations on reactions of molecules with metal surfaces
Promotor: Prof.dr. G.J. Kroes