545 zoekresultaten voor “into” in de Publieke website
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Learning class-imbalanced problems from the perspective of data intrinsic characteristics
The class-imbalance problem is a challenging classification task and is frequently encountered in real-world applications. Various techniques have been developed to improve the imbalanced classification performance theoretically and practically.
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Electrocatalytic reduction of CO2 and nitrate on immobilized metal porphyrins
M.T.M. Koper, Co-promotor: D.G.H. Hetterscheid
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Single-molecule microscopy in zebrafish embryos
Single-Molecule Microscopy (SMM) techniques constitute a group of powerful imaging tools that enable researchers to study the dynamic behavior of individual molecules.
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Wireless Random-Access Networks and Spectra of Random Graph
This thesis is divided into two parts. In Part I we study metastability properties of queue-based random-access protocols for wireless networks. The network is modeledas a bipartite graph whose edges represent interference constraints. In Part II we study spectra of inhomogeneous Erdős-Rényi random…
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Exploring the mechanisms of metastatic onset for novel treatment strategies
This thesis represents a comprehensive investigation into the control of cancer stemness and metastatic initiation using a combination of advanced zebrafish xenograft models and in vitro assays.
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Metals in LCIA
A critical look at the impact assessment modelling of metals in Life Cycle Impact Assessment and improvement options.
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Footprint family: Concepts, classification, integration, and benchmarking against planetary boundaries
How to bring together different footprints into an integrated family and what are the synergies? What are the roles of inventory analysis and characterization in measuring individual footprints and how these affect a footprint family? How to benchmark environmental footprints against related planetary…
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Targeting for success: Mechanistic insights into microRNA-based gene therapy for Huntington disease
Promotie
- Kaiser Lente Lezingen: Launching into the night — a brief history of space exploration
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Novel Imaging Insights into Cardiac Remodeling, Myocardial Function and Risk Stratification in Cardiovascular Disease
Promotie
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Studies into Interactive Didactic Approaches for Learning Software Design Using UML
Promotie
- Hutspot
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Biotic ligand models
Description of Biotic ligand models: making an inventory of available models & assessment of the variability of the predicted HC5 using the BLMs in different Dutch water types (2005 - 2007)
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Een gedreven buitenstaander: J.H. van 't Hoff de eerste Nobelprijswinnaar voor Scheikunde
This dissertation presents a new perspective on the life, work and character of the Dutch physical chemist Jacobus Henricus van ’t Hoff, first recipient of the Nobel Prize in Chemistry, and one of the most important and colourful scientists in Dutch history. The image of Van ’t Hoff that emerges from…
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The diverse roles of integrin α3β1 in cancer: Lessons learned from skin and breast carcinogenesis
In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.
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Exploring deep learning for multimodal understanding
This thesis mainly focuses on multimodal understanding and Visual Question Answering (VQA) via deep learning methods. For technical contributions, this thesis first focuses on improving multimodal fusion schemes via multi-stage vision-language interactions.
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On quantum transport in flat-band materials
The studies in this thesis are focused on the physical effects in the flat band materials. The results contain the discovery of strong enhancement of RKKY spin-spin interactions with specific geometric arrangement and dynamical generation of excitonic order parameter with high magnitude.
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Quantitative modelling of the response of earthworms to metals
Promotor: Prof.dr. W.J.G.M. Peijnenburg
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Decompositions in algebra
We show that Kirchhoff ’s law of conservation holds for non-commutative graph flows if and only if the graph is planar. We generalize the theory of (Euclidean) lattices to infinite dimension and consider the ring of algebraic integers as such a lattice.
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Bioorthogonal Antigens
The aim of this thesis is to explore the use of Bioorthogonal Antigens to study the cross-presentation pathway.
- Aflevering 9: Ruimterecht
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Understanding the Surface Structure of Catalysts and 2D Materials at the Atomic Scale
The work in this thesis demonstrates how to obtain an atomic-scale picture of a diverse set of complex surface structures observed using STM, under disparate conditions.
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Observing what cannot be observed: computational electrochemistry from carbon to hydrogen
In this thesis, we consider various (electro)chemical phenomena at surfaces and nanoparticles and their underlying atomistic processes, which we studied using first-principles methods such as density functional theory.
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Pyrrole-based photoswitchable anion receptors
The main goal of this thesis is to achieve advanced control of binding properties in bis-pyrrolic and macrocyclic pyrrolic receptors by light.
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Afdeling Industriële Ecologie (CML-IE)
The department of Industrial Ecology is dealing with research into the development of tools for decision making on sustainable production and consumption.
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Catalysis of the electrochemical water oxidation to oxygen
Promotor: Prof.dr. M.T.M. Koper, Co-Promotor: F. Calle-Vallejo
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Adjuvanted nanoparticulate seasonal influenza vaccines
Promotor: W. Jiskoot, Co-promotor: A. Kros
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From grains to planetesimals: the microphysics of dust coagulation
Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)
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On cluster algebras and topological string theory
My PhD research is devoted to studies of the conjectural cluster-algebraic symmetry in the theory of topological string, which is the simplest, however already non-trivial sector in the theory of string.
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Mechanistic modelling of drug target binding kinetics as determinant of the time course of drug action in vivo
Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.
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Harnessing zebrafish xenograft models for ocular melanoma treatment discovery
The aim of this thesis was to develop novel treatment strategies for different types of eye melanoma utilizing zebrafish models. We first establish orthotopic and ectopic xenograft models for uveal and conjunctival melanoma by engraftment of the immortalized cells derived from these tumors into zebrafish…
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The Agta of the Northern Sierra Madre. Livelihood strategies and resilience among Philippine hunter-gatherers
Promotores: G. Persoon, R. Schefold
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Star-Forming Galaxies at the Cosmic Dawn
Promotor: Prof.dr. M. Franx, Co-Promotor: Rychard Bouwens
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Interaction with sound for participatory systems and data sonification
This thesis deals with the use of sound in interactions in the context of participatory systems and data sonification. We investigate an interactive environment where participants perceive information of the data through sound elements.
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Material constraints of selected energy pathways
Examining if large scale application of new energy pathways can be constrained by materials and emissions.
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The LeiCNS-PK3.0 model development and applications: healthy-to-diseased CNS pharmacokinetic translation
Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…
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Electroextraction approaches for preconcentration of metabolites
In this thesis, we developed new ways to use a technique called electroextraction (EE) to extract charged molecules from one liquid into another using an electric field.
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Sustainable Chemistry and Biotechnology
If mankind wants to survive into the 22nd century, we will need to change the way we live drastically. The human impact on our planet is everywhere, we are changing the atmosphere, the oceans and the land, leading to global warming, climate change, loss of biodiversity and pervasive pollution. There…
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Synthetic peptides as tools in chemical immunology
This thesis has described novel synthetic methods to produce a variety of (glyco)peptides and their application in the study of various immunological processes.
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Lipidomics study in liver metabolic diseases
The ideas underlying this thesis are that lipidomics may improve the diagnosis of liver metabolic diseases, and can provide further insights into the underlying pathophysiology of these diseases.
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Rebekah Tromblé
Students Practicing Citizen Journalism
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Towards artificial photosynthesis: resolving supramolecular packing of artificial antennae chromophores through a hybrid approach
Promotor: H.J.M. de Groot
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Quantification of ecosystem services within river catchments
How can ecosystem services within river catchments be quantified in spatial and temporal explicit way?
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Effects of light at night on plants and their interactions with other species
What is the effect of light at night on plant phenology and physiology, and how does this affect plant interactions with other species?
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NanoFeed
Do selenium nanoparticles in fish food cause subtle alterations in behavior of fish: effect of particles size and concentration?
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Zicht op het zwarte gat
In samenwerking met Rijksmuseum Boerhaave, naar aanleiding van de tijdelijke tentoonstelling 'Dichter bij het zwarte gat', te zien t/m 5 januari 2025.
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The innate immune response against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf
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Multi-Objective Bayesian Global Optimization for Continuous Problems and Applications
A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.
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Quantitative live cell imaging of glucocorticoid receptor dynamics in the nucleus
In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.
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Parkinson’s protein α-synuclein: membrane interactions and fibril structure
The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.