615 zoekresultaten voor “medicine op make” in de Publieke website
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Disentangling a complex genus: systematics, biogeography and bioactivity of the genus Phyllanthus L. and related genera of tribe Phyllantheae
The largest genus within the Phyllanthaceae family is a group called Phyllanthus L. Recent studies have shown, that Phyllanthus is paraphyletic with the genera Glochidion, Breynia and Synostemon nested within it.
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Precision modeling of breast cancer in the CRISPR era
The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.
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Quantitative pharmacology of antimicrobials
Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.
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Ecology and genomics of Actinobacteria and their specialised metabolism
Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.
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Synthesis of Ribitol Phosphate based Wall Teichoic acids
Antibiotic resistance, caused by widespread use of antibiotics, leads to bacterial infections that are difficult, if not impossible, to treat and is a major worldwide health concern.
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Real-time tomographic reconstruction
With tomography it is possible to reconstruct the interior of an object without destroying.
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Fulltime programme
Het schema hieronder geeft het curriculum weer van het eenjarige fulltime programma van de master Health, Ageing and Society in collegejaar 2024-2025.
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Advanced in vitro models for studying drug induced toxicity
Promotor: B.van de Water, Co-promotor: L.S.Price
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LUGO student assistant (0.2 fte)
Bestuursbureau, Stafbureau, Bedrijfsvoering en Advies, Leiden University Green Office
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Een gedreven buitenstaander: J.H. van 't Hoff de eerste Nobelprijswinnaar voor Scheikunde
This dissertation presents a new perspective on the life, work and character of the Dutch physical chemist Jacobus Henricus van ’t Hoff, first recipient of the Nobel Prize in Chemistry, and one of the most important and colourful scientists in Dutch history. The image of Van ’t Hoff that emerges from…
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Nascholingsdag World Teachers Programme 2024
World Teachers Festival 2024 - Celebrating and exploring language, culture, diversity and criticality in teaching and learning
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On topological properties of massless fermions in a magnetic field
Make more fluid: In condensed matter systems, electrons can acquire unusual properties from their interaction with the atomic lattice.
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Quantifying nucleosome dynamicsand protein binding with PIE-FCCS and spFRET
In this thesis I describe the results of Pulsed Interleaved Excitation and Fluorescence (Cross) Correlation Spectroscopy (PIE-F(C)CS) combined with single-pair Förster Resonance Energy Transfer (spFRET) used to study dynamics in single nucleosomes, which depends on subtle differences in the length of…
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Macrophage activation and cholesterol in atherosclerosis development
Current therapies for patients with atherosclerosis are targeted primarily on reducing blood cholesterol, but this fails to prevent a large number of cardiovascular events.95 In order to identify new therapeutic strategies for treating atherosclerosis, it is important to study the interactions between…
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Exploring structure dependencies of gas-surface interactions with curved single crystals
Curved single crystals provide variable, but well-defined surface structures.
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Macrophage activation and cholesterol in atherosclerosis development
Promotores:Th.J.C. van Berkel, M. van Eck
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Is asylum bad for men (and better for women)? Changing perspectives on female and male refugees and asylum seekers in the Netherlands in the
Deelproject van
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Sustainable Chemistry and Biotechnology
If mankind wants to survive into the 22nd century, we will need to change the way we live drastically. The human impact on our planet is everywhere, we are changing the atmosphere, the oceans and the land, leading to global warming, climate change, loss of biodiversity and pervasive pollution. There…
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Electroextraction approaches for preconcentration of metabolites
In this thesis, we developed new ways to use a technique called electroextraction (EE) to extract charged molecules from one liquid into another using an electric field.
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Can predicting the future help us to make better decisions about our health?
Lezing
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AI-model voorspelt terugkeer van baarmoederkanker met grote nauwkeurigheid
Onderzoekers van het Leids Universitair Medisch Centrum (LUMC) hebben een AI-model ontwikkeld dat het risico op de terugkeer van baarmoederkanker nauwkeurig kan voorspellen.
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Lezing door Maxim Osipov: 'What Makes a Good Story Good? Reflections from behind the Writing Desk'
Lezing
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Assistant professor "Inflammation pathways in atherosclerosis"
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)
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From data to models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua
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Systems pharmacology of the endocannabinoid system
In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).
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Metabolomic characterization of plant exudates and their correlation with plant defense systems
Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
- Aflevering 33: Etniciteit in de middeleeuwen
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Systems diagnosis of chronic diseases, explored by metabolomics and ultra-weak photon emission
Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang
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PhD Candidate in Economics (0.8-1.0 fte)
Rechtsgeleerdheid
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‘Lab on a chip’ gaat gezondheidszorg ingrijpend veranderen
Snelle en goedkope chips die extreem kleine hoeveelheden vloeistof (microfluïden) analyseren vormen de kern van gepersonaliseerde gezondheidszorg. Maar het ‘laboratorium op een chip’ is nog niet effectief genoeg. Dr. Paul Vulto en zijn onderzoeksteam ontwikkelden een techniek die het gebruik van microfluïdische…
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Frank Baas
Faculteit Geneeskunde
f.baas@lumc.nl |
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Vergroten van Biodiversiteit op de Campus
Kijk regelmatig op deze pagina voor meer informatie over het vergroten van de biodiversiteit aan de Universiteit Leiden.
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Management of small-scale -African fisheries: The Case of Elephant Marsh in Malawi
How does the management of Elephant Marsh Fishery in Malawi relate to wider contexts of policies, theories and regions? And how can the current management system be adapted to achieve long-term sustainability of the fishery?
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Identification and characterization of viral Xrn1-resistant RNAs
Several single-stranded RNA viruses make use of Xrn1-resistant RNAs in their 3’ untranslated regions of their genome RNAs in order to increase their pathogenicity.
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Multi-Objective Bayesian Global Optimization for Continuous Problems and Applications
A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.
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Origami metamaterials : design, symmetries, and combinatorics
In the first part of this thesis we study the geometry of folding patterns.
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Opportunity and Problem in Context (OPiC). A framework for environmental management in developing countries
Promotor: W.T. de Groot
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Using cryo-EM methods to uncover structure and function of bacteriophages
Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.
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PNEC-pro
PNEC-pro is a user-friendly screening tool for professionals dealing with the assessment of surface water quality. The tool calculates local, watertype specific no-effect concentrations (PNEC) of copper, lead, nickel and zinc based on biotic ligand models (BLMs).
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On transport properties of Majorana fermions in superconductors: free & interacting
Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.
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Electrical and magnetic properties of ferritin: electron transport phenomena and electron paramagnetic resonance
Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.
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The noisy underwater world: the effect of sound on behaviour of captive zebrafish
Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn
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Zebrafish embryos and larvae as a complementary model for behavioural research
Promotor: Prof.dr. M.K. Richardson
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Inferno Worlds
A remarkable population of short period transiting rocky exoplanets with equilibrium temperatures on the order of 2,000 K has recently been discovered.
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Impact assessment modelling of matter-less stressors in the context of Life Cycle Assessment
Promotoren: Prof.dr. G.R. de Snoo en Dr. R. Heijungs
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Methods to simulate fermions on quantum computers with hardware limitations
This thesis is a collection of theoretical works aiming at adjusting quantum algorithms to the hardware of quantum computers.
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Liposome-based synthetic long peptide vaccines for cancer immunotherapy
Promotores: Wim Jiskoot; Ferry Ossendorp
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Chemical Similarity: Structuring Risk and Hazard Assessment
At the moment, over 350.000 chemicals are registered worldwide for production and use. Their application, however, may harm human health and the environment.
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Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantation - a delicate balance
Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius