In this thesis we study bistable reaction-diffusion equations on lattice domains.

Promotor: W. T. F. den Hollander, F. H. J. Redig

Promotor: P.D. Grünwald

Principles of Environmental Sciences provides a comprehensive picture of the principles, concepts and methods that are applicable to problems originating from the interaction between the living and non-living environment and mankind. Both the analysis of such problems and the way solutions to environmental…

Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.

This dissertation investigates the energy and material related impacts of the transition towards a low-carbon heating system in the Netherlands, in the context of its 2050 climate and circular economy policy goals.

Promotores: Prof.dr. J.N. Kok, Prof.dr. C.A. Mandemakers, Co-Promotor: G. Bloothooft

Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)

Promotor: A. Kros

Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez.

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

Promotors: Prof.dr. G.R. de Snoo, Prof.dr. H. Leirs (Univ. Antwerpen)

The parabolic Anderson model (PAM), which is the Cauchy problem for the heat equation with random potential. The PAM is a mathematical model that describes how mass (i.e. matter or energy) flows in a medium in the presence of a field of sources and sinks.

The application of nanomaterials in industrial processes and consumer products provides many societal benefits, but can also lead to the release of nanomaterials into the environment. The work in this dissertation aims to provide insights into the potential environmental impacts that may follow from…

In this thesis, I focused on studying the above- and belowground interactions of J. vulgaris from a plant-soil feedback (hereafter, PSF) perspective. I investigated the temporal variation of negative PSF and examined the effects of root-associated bacteria on plant performance and aboveground herbiv…

Chinese materia medica (CMM), comprising a diverse array of natural substances from plants, animals, and minerals, has been integral to Traditional Chinese Medicine (TCM) throughout history. This study investigates the dynamic evolution of CMM, noting shifts in species for improved therapeutic effects…

This thesis explores Breaking of Ensemble Equivalence (BEE) in random graph models by examining the spectral properties of adjacency matrices. The goal is to identify spectral characteristics that differentiate random graph ensembles, enhancing the understanding of complex network structures and beh…

Monoacylglycerol lipase (MAGL) is the principal enzyme responsible for hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG). MAGL inhibition provides several potential therapeutic opportunities, including anti-nociceptive, anti-inflammatory and anti-cancer activity.

The global agri-food system plays a critical role in food security and environmental issues.

Promotores: Prof.dr. G.A. Persoon & Prof. dr. H.H. de Iongh

Op 7 februari 2019 verdedigde Helena Ursic-Vrabec haar proefschrift 'Uncontrollable: Data subject rights and the data- driven economy'. Het promotieonderzoek is begeleid door promotor prof. dr. S. van der Hof.

The expedition commanded by Nicolas Baudin to Tenerife, Mauritius, Australia, Timor and South Africa in 1800-1804 is fully researched in regard to ornithology.

A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.

Promotores: Prof.dr. H.J.M. de Groot, Prof.dr. J. Matysik (Universitaet Leipzig)

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.

Ethiopian wolves are endangered diurnal Afroalpine rodent hunters. I investigated the interaction between wolves, rodents and human land use in Borena Sayint National Park (BSNP), Abune Yosef and Aboi Gara in Ethiopia.

Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…

Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.

Comparing the global warming potential (GWP) of the service provided by an iRex Digital Reader to the same service provided by an office printer using a scanning LCA.

If X is a locally compact Hausdorff space, then a representation of the complex C* algebra C_0(X) on a Hilbert space $H$ is given by a spectral measure that takes its values in the orthogonal projections on $H$.

Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.

The majority (80%) of e-waste generated globally are recycled informally in developing countries.

1. To what extent do metallic NPs added to soil extractions change the activity, abundance, or community composition of microbes? 2. How do the effects of metallic NPs on soil microbes differ from the effects of the ions shedding from corresponding NPs?

Computers zijn in staat om ongelooflijk nauwkeurige voorspellingen te doen op basis van machine learning. Met andere woorden, deze computers kunnen zonder tussenkomst leren als ze eenmaal door mensen zijn voorgeprogrammeerd. Bij LIACS verkennen en verleggen we de grenzen van wat een revolutionaire nieuwe…

Wiskunde en Natuurwetenschappen, Centrum voor Milieuwetenschappen Leiden (CML)

Prof.dr. Rozenberg, emeritus hoogleraar Theoretische Informatica aan het Leiden Institute of Advanced Computer Science (LIACS), ontving op 15 december 2017 een koninklijke onderscheiding uit handen van de locoburgemeester van Leiden. Hij is benoemd tot Ridder in de Orde van de Nederlandse Leeuw.

Je kunt aan de Universiteit Leiden Kunstmatige Intelligentie studeren, maar ook binnen andere opleidingen speelt het een steeds grotere rol.

We leveren fenotypische read- outs voor diagnose en patiënt stratificatie voor een behandeling op basis van innovatieve metabolomics, UPE en organ-on-a-chip technologie. Met een farmacologische én biologische aanpak bieden we inzicht in ziektemechanismen en vertalen dat voor de gepersonaliseerde gen…

What is movements and corridors of the Bornean pygmy elephant in Sebuku forest? What is the nature of human-elephant conflict in Nunukan District in time and space? What are the diets of the Bornean elephants related to crop raiding?

The aims of the project are to: further clarify 'inhibition by safety'; explore and describe all possible sagety factors, with a special focus on the primary human safety source: social connectedness; reviewing prolonged stress responses without stressors.

What performance criteria does a new technology have to fulfill in order to be added to the list of future energy options and what constraints exist in terms of broad market penetration?

LIACS is a partner in the EU Erasmus+ Curriculum Development for the Asian education system. The knowledge available in the field of Data Science and Artificial Intelligence education will be shared and adapted for the Asian market.

Developing methodes to understand the evolution of patches in natural ecosystems

Accumulation of metals in economy and environment and its associated risks, within the Netherlands and the EU.