734 zoekresultaten voor “random were in room environments” in de Publieke website
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George Orwell: Such, such were the joys
Lezing, Studium Generale
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Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination
CONCLUSION: This study demonstrates that human macrophages can be induced to exert direct anti-tumor activity against osteosarcoma cells. Our observation that the induction of macrophage anti-tumor activity by L-MTP-PE required IFN-gamma may be of relevance for the optimization of L-MTP-PE therapy in…
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Studies on the Pathogenesis of Chronic Kidney Disease
In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…
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Core cross-linked polymeric micelles based on polypept(o)ides: from secondary structure formation of polypeptides to functional cross-linking
This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.
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The structure of the cytochrome P450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography
Promotor: Prof.dr. M. Ubbink
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Effects of pesticides on aquatic macrofauna in the field
Promotores: W.J.G.M. Peijnenburg, G.R. de Snoo, Co-promotor: M.G. Vijver
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Integrated Chain Management in the Province of Limburg
The cases of building materials, automobility, mushrooms and plastics.
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The World of Water
The International Course on Water Use and Management in Cagayan Valley The Philippines (2011-2015)
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Conductance and gating effects at sputtered oxide interfaces
This thesis explores interfacial conductance and electric field-effects in LaAlO3/SrTiO3 heterostructures.
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Pesticides Atlas, Pilot Study
Description of Atlas of the surfacewater concentrations of pesticides in the Netherlands, a pilotstudy.
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Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
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Systematics, Epidermal defense and Bioprospecting of Wild Orchids
This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.
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Growth and Transport properties of (Rare Earth)TiO3 / SrTiO3 interfaces
This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.
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Understanding functional dynamics and conformational stability of beta-glycosidases
Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.
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De verzamelwoede van Martinus van Marum (1750-1837) en de ouderdom van de aarde
Promotor: F.J. van Lunteren, E. Jorin
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Towards controlled microneedle-mediated intradermal immunization
Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.
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Evolution and development of orchid flowers and fruits
To gain more insight into the evolutionary development of orchid flowers and fruits, the orchid species Erycina pusilla was studied. The evolutionary origin of the median petaloid sepal, the callus on the labellum, and the stelidia was studied.
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Confronting Hydrodynamic Simulations with New Observations of High-density Environments
Promotie
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cryo EM tools to study the ultrastructure of microbes in changing environments
Promotie
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LIBC Onderzoeksfaciliteiten
Faciliteiten waar LIBC leden gebruik van kunnen maken (in het Engels):
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Tuning in to star-planet interactions at radio wavelengths
Low-mass main-sequence stars like our Sun are continuous sources of outflowing hot magnetised plasma. In the case of the Sun, this is known as the solar wind, whereas for other stars they are called stellar winds.
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Phylogenetic ecology of octocoral - gastropod associations
Promotor: E. Gittenberger, Co-promotores: L.P. van Ofwegen; B.W. Hoeksema
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Biophysical feedbacks between seagrasses and hydrodynamics in relation to grazing, water quality and spatial heterogeneity
Consequences for sediment stability and seston trapping
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Protostellar jets and planet-forming disks: Witnessing the formation of Solar System analogues with interferometry
The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.
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Infrared spectroscopy of astrophysically relevant hydrocarbons
This thesis is about the study of hydrocarbons via infrared spectroscopy.
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Arguably augmented reality : relationships between the virtual and the real
This thesis is about augmented reality (AR). AR is commonly considered a technology that integrates virtual images into a user’s view of the real world.
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Real-time foresight: preparedness for dynamic innovation networks
Promotor: H.J. van den Herik, B.R. Katzy, Co-promotor: K. Sailer
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Clues from stellar catastrophes
Promotores: S.F. Portegies Zwart, E. M. Rossi
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The Ecology and Evolution of Microbial Warfare in Streptomyces
The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.
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Deelnemende teams 2019
Benieuwd wie er in 2019 allemaal aan de start zijn verschenen? Bekijk onderstaande lijst:
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Algorithms for analyzing and mining real-world graphs
Promotor: Prof.dr. J.N. Kok, Co-Promotor: W.A. Kosters
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Analysis and Stochastics
The research of the Applied Mathematics cluster is concerned with such diverse topics as dynamical systems, representation theory, differential equations and pattern recognition.
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LCN2 Seminars
Een maandelijks seminar over complexe netwerken, gericht op wetenschappers uit alle disciplines.
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Growth-induced self-organization in bacterial colonies
Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.
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Bayes and Networks
Promotor: A.W. van der Vaart
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Scattering and absorption in 2D optics
Scattering of light in the presence of nano-structured materials, i.e. with features in the order of the wavelength of the light or smaller, reveals details of how light interacts with matter at the nanoscale.
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Insights from scanning tunneling microscopy experiments into correlated electron systems
This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.
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Machine learning for radio galaxy morphology analysis
We explored how to morphologically classify well-resolved jetted radio-loud active galactic nuclei (RLAGN) in the LOw Frequency Array (LOFAR) Two-metre Sky Survey (LoTSS) using machine learning.
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On electronic signatures of topological superconductivity
Promotor: Prof.dr. C.W.J. Beenakker
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Steady-State Analysis of Large Scale Systems
Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma
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K-pop
Kunst en vrije tijd, Kunst en vrije tijd
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Evolution of Molecular Resistance to Snake Venom α-Neurotoxins in Vertebrates
We have examined sequences from the ligand-binding domain of the nicotinic acetyl choline receptor (nAChR) in 148 vertebrate species. We are in interested in this receptor because the α-neurotoxins of many venomous snakes binds to this receptor in its location at the neuromuscular junction in all ve…
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Hybrid zone dynamics in amphibians
Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.
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Ruthenium- and cobalt-based artificial metalloenzymes for photocatalytic water oxidation in artificial photosynthesis
Producing green energy has become the main goal in our society in the search of reducing or eliminating the carbon emission from fossil fuels.
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Discovery of BUB1 kinase inhibitors for the treatment of cancer
The spindle-assembly checkpoint (SAC) is a safety mechanism which secures accurate chromosome segregation during mitosis.
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RNA splicing in breast cancer progression
In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.
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Imaging complex model catalysts in action
From surface science towards industrial practice using high-pressure scanning tunneling microscopy.
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The ecological relevance of chemical diversity in plants
Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder
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Coiled-coils on lipid membranes: a new perspective on membrane fusion
Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros
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Invertebrate response to management of roadside edges
Does roadside management in the mid-west USA increase invertebrate diversity similar to practices in Europe?