Promotoren: Prof.dr. G.R. de Snoo en Dr. R. Heijungs

This thesis is a collection of theoretical works aiming at adjusting quantum algorithms to the hardware of quantum computers.

Promotor: Prof.dr. G.P. van Wezel

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

Promotor: Peter Stevenhagen

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

This thesis applies data mining in commercial settings in the telecommunications industry.

Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken

The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.

Taxonomy as a science has accumulated data and knowledge for more than 250 years.

This work is dedicated to interpreting in cohomological terms the special values of zeta functions of arithmetic schemes.

Cathodic corrosion is a relatively unknown phenomenon that can severely etch metallic electrodes at cathodic (negative) potentials.

Promotor: J. N. Kok, Co-promotor: A. J. Knobbe

This thesis is largely an experimental study on the formation of solid-state simple and complex organic molecules in the H2O-rich and CO-rich ice phases of dense interstellar clouds and dark cores.

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.

In this work, we illustrate unconventional approaches towards the fabrication of edge functionalized graphene nanostructures and bidimensional architectures in polymeric and metallic supports, with an outlook towards molecular sensing devices.

This thesis presents pioneering work on the panchromatic emission of some of the most luminous galaxies in the early Universe: star forming galaxies and active galactic nuclei.

The high velocity tail of the total velocity distribution of stars provides essential insight into fundamental properties of the Galaxy.

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Promotor: Roeland M.H. Merks

What is the best way to combine the environmental and economic data and how can we create an operational system to do so, thereby supporting the delivery of data to the Data centres on Products and Resources?

This work describes several studies into the electroreduction of carbon dioxide (CO2RR), both regarding mechanistical aspects and catalyst stability considerations. Mechanistic insights into carbon-carbon bond formation on a silver catalyst are described in Ch 2, were we find an acetaldehyde-like surface…

The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.

In this thesis, the role of plant-mediated soil legacy effects in shaping aboveground plant-insect interactions was investigated.

Promotor: A. Kros

The following report discusses a survey on the topic of the Sustainable Development Goals that was distributed among researchers at Leiden University in the month of November 2021.

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.

Laboratory, observation and modeling work on the dissociation of polycyclic aromatic hydrocarbons in interstellar environments and the formation of new molecular species through the fragmentation process.

A brief review essay on some of the work that has been recently published in the emergent field of digital ethnography.

This course uses the lives, ideals and achievements of Theodore, Franklin, and Eleanor Roosevelt to create the idea of a Rooseveltian century. It is an invitation to think critically and historically, and it wants to give you a glimpse of what it means to be a historian at work.

This course provides an insider perspective into the work of international criminal courts and tribunals. You will learn about the investigation and prosecution of international crimes in The Hague.

Het tijdschrift 'East European Politics' publiceert artikelen over politiek, bestuur en internationale betrekkingen van de post-communistische landen.

Public Administration is a major refereed journal publishing articles on public administration, public policy and public management.

Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea

Res Publica een Nederlandstalige wetenschappelijk tijdschrift voor politieke wetenschap, bestuurskunde, Europese en internationale politiek, politieke sociologie en communicatiewetenschap.

Regional & Federal biedt een wetenschappelijk platform aan wetenschappers die zich bezighouden met internationaal onderzoek op deze gebieden.

Acta Politica is het officiële wetenschappelijke tijdschrift van de Nederlandse Kring voor de Wetenschap der Politiek.

Wiskunde en Natuurwetenschappen, Mathematisch Instituut (MI)

Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)

The key purpose of this project is to study tautological relations on the level of closed differential forms or even integral cochains (i.e. we don't take classes in cohomology).

The coursework within the Science Communication and Society (SCS) specialisation prepares students for internships and a career in communication about science and health.

The work presented in this thesis is based on ALMA surveys of protoplanetary disks in three star-forming regions: Lupus, OMC-2, and NGC 2024.

The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.

The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

Creating a framework to assess the sustainability of fish farms which will set sustainability standards and give consumers information about the the sustainability and safety of their seafood.

Machine Learning is becoming a more and more substantial technology for industry.

In this work, we investigate the minute circular dichroism effects of single nanoparticles.To this aim, we apply photothermal imaging with a polarization-modulated heating beam.

PhDArts co-director Dr. Janneke Wesseling’s e-book ‘De volmaakte beschouwer, De ervaring van het kunstwerk en receptie-esthetica’ was recently published. The key question of the book is: how does the work of art work?