What are the main factors associated with the stranding of the two seal species? What are the factors influencing the prevalence of disease in the two species? Which human-related factors influence the populations of the two seal species?

The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.

Wetland plants are distinguished from plants of other terrestrial ecosystems by their adaptations to specific habitat stresses, including waterlogged and flooding and the subsequent abundance of phytotoxic compounds.

Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.

Promotor: A.P. IJzerman Co-promotor: L.H. Heitman

In de podcast Historische BoekenCast van Historisch Nieuwsblad bespreekt Manon van der Heijden het boek New York in brand van de Amerikaanse historicus Jill Lepore.

Hoe zag de betrokkenheid van het Britse koningshuis bij de slavernij eruit? Op deze vraag probeert alumnus Camilla de Koning een antwoord te vinden. NOS.nl besteedde aandacht aan dit onderzoek.

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

There is a need for alternative methods to replace, reduce and refine (3R) animal experimentation. Combining experimental data from high-throughput in vitro studies with in silico modeling is a promising approach to unravel the effect of chemicals on living cells and to gain a better understanding of…

Safety issues of the transport and storage of Chlorine, ammonia and LPG.

Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.

Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.

The overall objectives of my thesis are to investigate the dynamics of the sorghum root microbiome and to explore the beneficial effects of the root microbiome on sorghum growth and stress tolerance.

Promotor: Prof.dr. R. Verpoorte, Co-Promotores: N.R. Mustafa, A.E. Schulte

This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.

An objective of this research was to achieve direct, well-defined and non-rate-limiting electron transfer between respiratory enzymes and the electrode surface by means of 'Q-wires'.

This thesis is a collection of experimental attempts to enhance photoluminescence of fluorescent molecules and quantum dots with single gold nanorods (GNRs) and relevant applications.

Promotor: M. Ubbink, Co-promotor: G. Siegal

The formation of stars and planets happens over multiple scales, which can interact. In particular, planet formation happens in the dense, complex environment of star forming regions.

This thesis describes the design, synthesis, and immunological evaluation of varying (neo)antigenic peptide conjugates containing either a TLR2 or a TLR7 agonist.

Indonesia is experiencing various environmental challenges related to its fast economic growth. Therefore, it is necessary to have measurable and applicable indicators to obtain accurate data and information regarding the costs of adverse environmental impacts arising from economic activities to support…

The research described in this thesis focused on the preparation of S/N functionalized carbene ligands and their transition metal complexes, and the exploration of their application as electrocatalysts for proton reduction.

The research in this dissertation aims to optimise blood donation processes in the framework of the Dutch national blood bank Sanquin. The primary health risk for blood donors is iron deficiency, which is evaluated based on donors' hemoglobin and ferritin levels.

Hoe kan de techniek van cell wall engineering worden ingezet zodat de industrie streptomyceten beter kunnen verwerken tot nieuwe antibiotica?

Sinds 1 september 2014 werkt Jürgen K. Zangenberg als hoogleraar Cultuur en Geschiedenis van het Antieke Jodendom en het Vroege Christendom bij het Instituut voor Geschiedenis én bij LUCAS. Ook is hij opleidingsvoorzitter van de een- en tweejarige masteropleidingen Classics and Ancient Civilizations.…

Sinds 1 januari 2015 is Johan van de Worp als promovendus verbonden aan het Instituut voor Geschiedenis. Onder supervisie van prof. dr. B. Schoenmaker en mevr. dr. A.M.C. van Dissel verricht hij onderzoek naar de werving, opleiding en levensomstandigheden van het mindere marinepersoneel gedurende de…

Promotor: S.M. Verduyn Lunel

In light of climate change, it is crucial to determine whether plant species can adapt to future climates to avoid extinction. Plants adapt to various conditions by altering their functional traits, such as leaf size or photosynthetic rate. Some traits appear linked and vary together between species,…

Promotor: Prof.dr. A.G.G.M. Tielens

Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman

Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort

Control of infectious diseases poses continuous challenges for human health.

Climate change is one of the largest challenges faced by humanity. To combat this research into alternatives to fossil fuels is ongoing. Dihydrogen is considered a good alternative fuel, since its burning only forms water.

Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.

Op 11 december 2012 is de eerste aflevering van ‘De Gouden Eeuw’ uitgezonden. Deze serie, gemaakt door de geschiedenisafdeling van NTR en VPRO belicht in dertien afleveringen het verhaal van deze fascinerende en belangrijke periode. In een aantal afleveringen komen Leidse historici aan het woord.

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn

Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh

Streptomyces bacteria are a valuable source of natural products, many of which are used in the clinic or in biotechnology.

Promotor: K.H. Kuijken

The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.

With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.

This report investigates the different approaches in the authorization process of GMOs for commercial use in the European Union and the United States of America. Three main aspects are considered and analyzed as potential causes of differences in the authorization process of GMOs for commercial use.…

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.

Promotor: A.P. IJzerman

Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.

On the largest scale, the Universe resembles a cosmic spiderweb. Most galaxies coexist in small groups within the threads of this web. At the nodes of the threads are enormous groups of galaxies forming the largest structures in the universe still held together by gravity: clusters of galaxies.

Machine Learning is becoming a more and more substantial technology for industry.