5,372 zoekresultaten voor “history of centrum and ester europese” in de Publieke website
-
Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
-
nucleosome dynamics modulated by histone modifications, histone variants and neighboring nucleosomes
Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort
-
Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
-
Artificial metallo-proteins for photocatalytic water splitting: stability and activity in artificial photosynthesis
Climate change is one of the largest challenges faced by humanity. To combat this research into alternatives to fossil fuels is ongoing. Dihydrogen is considered a good alternative fuel, since its burning only forms water.
-
The spin evolution of accreting and radio pulsars in binary systems
Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.
-
Leo Lucassen bij De Morgen over Europees migratiebeleid
Het migratiebeleid van de Europese Unie lijkt er steeds meer op gericht om meer muren te bouwen. Hoogleraar migratiegeschiedenis Leo Lucassen praat bij De Morgen over hoe het beleid aan het radicaliseren is - zowel rechts als links.
-
Kennismaking met Jürgen Zangenberg
Sinds 1 september 2014 werkt Jürgen K. Zangenberg als hoogleraar Cultuur en Geschiedenis van het Antieke Jodendom en het Vroege Christendom bij het Instituut voor Geschiedenis én bij LUCAS. Ook is hij opleidingsvoorzitter van de een- en tweejarige masteropleidingen Classics and Ancient Civilizations.…
-
Even voorstellen: Johan van de Worp
Sinds 1 januari 2015 is Johan van de Worp als promovendus verbonden aan het Instituut voor Geschiedenis. Onder supervisie van prof. dr. B. Schoenmaker en mevr. dr. A.M.C. van Dissel verricht hij onderzoek naar de werving, opleiding en levensomstandigheden van het mindere marinepersoneel gedurende de…
-
Bearing with noise: The effects of highway noise on behaviour and development in zebra finches
Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.
-
In vitro and in vivo delivery of functionalized nanoparticles via coiled-coil interactions
Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn
-
Inextricable ties between chemical complexity and dynamics of embedded protostellar regions
Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh
-
of the angucycline biosynthetic gene cluster in Streptomyces sp. QL37 and implications for lugdunomycin production
Streptomyces bacteria are a valuable source of natural products, many of which are used in the clinic or in biotechnology.
-
Structure and substructure in the stellar halo of the Milky Way
Promotor: K.H. Kuijken
-
into the role of ceramide subclass composition on lipid organization and skin barrier
The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.
-
Strategies for braiding and ground state preparation in digital quantum hardware
With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.
-
EPCEM 2001: Differences in the authorization process of GMOs in the EU and the USA
This report investigates the different approaches in the authorization process of GMOs for commercial use in the European Union and the United States of America. Three main aspects are considered and analyzed as potential causes of differences in the authorization process of GMOs for commercial use.…
-
Properties of Single Server Queueing Systems: Efficient Methods via Lumping and Dynamic Programming
This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.
-
Nucleosome stacking in chromatin fibers probed with single-molecule force- and torque-spectroscopy
In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.
-
dimension of environmental Life Cycle Assessment: addressing choice, future and interpretation uncertainties.
LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.
-
Allosteric modulation by sodium ions and amilorides of G protein- coupled receptors
Promotor: A.P. IJzerman
-
Genetic and environmental factors determining heterogeneity in preservation stress resistance of Aspergillus niger conidia
Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.
-
Untangling cosmic collisions: a study of particle acceleration and magnetic fields in merging galaxy clusters
On the largest scale, the Universe resembles a cosmic spiderweb. Most galaxies coexist in small groups within the threads of this web. At the nodes of the threads are enormous groups of galaxies forming the largest structures in the universe still held together by gravity: clusters of galaxies.
-
Data-Driven Machine Learning and Optimization Pipelines for Real- World Applications
Machine Learning is becoming a more and more substantial technology for industry.
-
Systems diagnosis of chronic diseases, explored by metabolomics and ultra-weak photon emission
Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang
-
Clavis Aurea? Structure-enabled approaches of identifying and optimizing GPCR ligands
Promotores: A.P. IJzerman, H.W.T. van Vlijmen
-
Applications of Natural Deep Eutectic Solvents to Extraction and Preservation of Biomolecules
The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.
-
Allosteric modulation by sodium ions and amilorides of G protein-coupled receptors
Promotor: A.P. IJzerman
-
for spatially-resolved omics data at single cell resolution: Methods and Applications
The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…
-
Subsidie voor kunstproject WeCurate
Hoe moeten kunstorganisaties hun veranderende rol in de samenleving gaan invullen? In het project WeCurate zoeken kunstenaars, kunstinstellingen en publiek samen naar een antwoord. Kunsthistorica Kitty Zijlmans kreeg er een Europese subsidie van ruim 118.000 euro voor.
-
Twitteren over middeleeuwse handschriften
Dr. Erik Kwakkel staat met het ene been in de wereld van middeleeuwse boekproductie en met het andere stevig in de moderne sociale media. Hij is co-auteur van Author, Reader, Book, een werk over middeleeuws schrijverschap, en hij twittert dagelijks over het onderwerp.
-
Sanne Wirken wint Master scriptieprijs 2014
De winnaar van de Master scriptieprijs 2014 van het Holland Historisch Tijdschrift is niemand minder dan alumna van de Universiteit Leiden Sanne Wirken, met haar scriptie Jan Kluit en Hendrik Moerings. Media en identiteit in de Republiek, 1747 – 1800.
-
Quantifying nucleosome dynamicsand protein binding with PIE-FCCS and spFRET
In this thesis I describe the results of Pulsed Interleaved Excitation and Fluorescence (Cross) Correlation Spectroscopy (PIE-F(C)CS) combined with single-pair Förster Resonance Energy Transfer (spFRET) used to study dynamics in single nucleosomes, which depends on subtle differences in the length of…
-
Global metabolomics and lipidomics approaches to probe virus-host interactions
The outbreaks of AIDS and COVID-19 showed clearly how infectious viruses can influence people’s lives. Investigating the changes in the host metabolism may provide a paradigm shift to consider immune-metabolic interactions as therapeutic targets.
-
Feedback from deeply embedded low- and high-mass protostars. Surveying hot molecular gas with Herschel
Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg
-
Bioorthogonal deprotection strategy to study T-cell activation and cross- presentation
Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.
-
Nadine Akkerman bij Nieuws & Co op NPO 1 over haar grote Europese subsidie
Nadine Akkerman heeft een subsidie van twee miljoen euro ontvangen van de European Research Council (ERC) voor onderzoek naar Engelse manuscripten uit de 16e en 17e eeuw. Zij sprak in het radioprogramma Nieuws & Co op NPO Radio 1 over haar onderzoek en de subsidie.
-
Poiesis and the Performance Practice of Physically Polyphonic Notations
Kevin speelt hedendaags repertoire dat zich onderscheidt doordat de lichamelijk handelingen die nodig zijn om deze muziek uit te voeren in de notatie van elkaar losgekoppeld zijn. Dit heet ook wel physical polyphonic notations, een unieke en relatief recente trend in de muziek waarbij naast de noten…
-
Probing the darkness: the link between baryons and dark matter
Promotor: Prof.dr. J. Schaye, Co-promotor: Marcello Cacciato
-
Liberal Arts and Sciences: Global Challenges (BA/BSc)
Bij Leiden University College The Hague staan Global Challenges centraal. Global Challenges zijn de grote, maatschappelijke uitdagingen van de 21ste eeuw waar we gezamenlijk een oplossing voor moeten vinden, zoals klimaatverandering, armoede, ongelijkheid, vrede en recht. Onze opleiding is opgesplitst…
-
Matthias Haentjens en Jouke Tegelaar bij de AFM over de Europese dimensie van gerechtelijke toetsing van toezicht
Matthias Haentjens en Jouke Tegelaar spraken op dinsdag 22 mei bij de Autoriteit Financiële Markten (AFM) over de Europese dimensie van gerechtelijke toetsing van toezicht.
-
Flitsinterview met alumna en Europese Commissie beleidsjurist Helena Loutas-Paraskeva
Direct na ons universitaire Brussels Alumni Event, ontmoette ik (externe relaties officer M. Blaauw, red) onze eigen Leiden Law alumna Helena-Loutas Paraskeva. Een Australische die werkzaam is voor de Europese Commissie. Interessant, hoe komt ze daar terecht, wat doet ze precies en in hoeverre heeft…
-
Workshop The Natural World (Antwerpen)
ENVIRHUS (Environmental and Rural History of Urbanized Societies) organiseert op 17 februari 2023 (14u-17u) de workshop ‘The Natural World‘.
-
Vacancy - PhD Position at the University of Groningen
PhD Position in Christianity and the History of Ideas (University of Groningen) (deadline for submission: 17 May 2020).
-
near-surface environment in tuning electrochemical CO2 reduction reaction and H2 evolution reaction
This thesis has shed light on some of the ways in which the local electrolyte composition can differ from the bulk and how these changes in the local reaction environment can determine the activity and/or selectivity of two important electrocatalytic reactions, namely, electrochemical CO2 reduction…
-
Identification of Therapeutic Targets and Antisense Oligonucleotide Mediated Exon Skipping Based Therapies in Arthritis
Promotor: G.J.B. van Ommen
-
Synthetic peptides, nucleic acids and molecular probes to study ADP-Ribosylation
This thesis presents the first synthetic peptides ADP-ribosylated on serine, threonine, tyrosine, arginine and cysteine.
-
Stem! Sanne Frequin genomineerd voor Vrouw in de Media Awards 2019
Sanne Frequin, kunsthistorica en universitair docent, maakt kans op de Vrouw in de Media Award 2019 voor de provincie Noord-Holland. Ze is genomineerd naar aanleiding van haar berichtgeving over de brand in de Notre Dame.
-
Alumna Erica Boersma wint eerste Roggeveen-scriptieprijs
De Leidse geschiedenis-alumna Erica Boersma heeft op 12 december eerste de Roggeveen-scriptieprijs voor geschiedenis van het Koninklijk Zeeuwsch Genootschap der Wetenschappen gewonnen voor haar Research Masterscriptie 'De Republiek als barmhartige Samaritaan. Collectes voor buitenlandse geloofsgenoten…
-
Frank de Hoog wint scriptieprijs Historisch Tijdschrift Holland
Frank de Hoog (momenteel Research Master student) won in mei 2013 de scriptieprijs van het Historisch Tijdschrift Holland.
-
The LeiCNS-PK3.0 model development and applications: healthy-to-diseased CNS pharmacokinetic translation
Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…