The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

Promotor: Prof.dr. J. den Hertog

Promotor: Prof.dr. T. Schmidt

Promotor: S.M. Verduyn Lunel, Co-promotor: O. van Gaans

In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

Politicologische studie naar de opzet, samenstelling en het functioneren van parlementaire commissies.

Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans

Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez.

This course explains the functions of each international court and tribunal in The Hague. On the basis of cases and interviews with judges and lawyers, this course explores the role of these courts and tribunals and their potential to contribute to global justice.

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Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.

This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.

Vinasse is a major by-product generated by the sugarcane biofuel industry. It is a source of microbes, nutrients and organic matter and often it is recycled as fertilizer.

Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…

Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

Digitalisering van de samenleving is een wereldwijde uitdaging. Robots nemen niet alleen steeds meer taken over van de mens, maar verslaan zelfs de wereldkampioen van de moeilijkste denksporten.

Op vrijdag 17 september 2021 sprak prof.dr.ing. Bram Klievink zijn oratie uit getiteld: 'Hollen én stilstaan: hoe data en digitalisering de overheid veranderen'.

De afdeling Beleid en Innovatie van het Instituut Bestuurskunde richt zich op het vormgeven, implementeren en evalueren van beleid met innovatieve benaderingen. Ons doel is om complexe maatschappelijke uitdagingen aan te pakken door technologische vooruitgang en creatieve beleidsinstrumenten te onde…

Evolution acts via mutations in amino acid sequences. Substitution of essential amino acids leads to a nonfunctional protein. l.

Promotores: Prof.dr. J. Schaye, Prof.dr. S.D.M. White (MPA Garching)

The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.

Het College van Bestuur heeft besloten de elf profileringsgebieden onderzoek van de universiteit elk een subsidie van € 1 miljoen toe te kennen over de periode 2010 tot en met 2014. Het LUMC draagt ook bij aan de subsidies in de gebieden waarin het LUMC participeert.

How can ecosystem services within river catchments be quantified in spatial and temporal explicit way?

Do e-waste workers display enhanced effects of adverse health effects due to informal e-waste processing in Nigeria? Is there a difference between the health outcomes of the exposed and the control groups? Are there difference in health effects within and between job groups (collectors, dismantlers,…

Hogere temperaturen leiden wereldwijd tot veranderingen in de vegetatie en de bodem van berggebieden. Een internationaal onderzoeksteam met de Leidse ecoloog Ellen Cieraad publiceerde op 25 januari in Nature over de verstoring van het ecosysteem.

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Op 18 september 2019 verdedigde Huw Llewellyn zijn proefschrift 'An Institutional Perspective on the United Nations Criminal Tribunals: Governance, Independence and Impartiality'. Het promotieonderzoek is begeleid door promotoren prof.dr. N.M. Blokker en prof.dr. L.J. van den Herik.

BioSolar Cells is a five-year research project in which ten knowledge institutions and 45 private industries work together.

Cardiovascular diseases are still a major concern for the global health.

The studies in this thesis are focused on the physical effects in the flat band materials. The results contain the discovery of strong enhancement of RKKY spin-spin interactions with specific geometric arrangement and dynamical generation of excitonic order parameter with high magnitude.

Triplet superconductivity refers to a condensate of equal-spin Cooper pairs (pairs of electrons with equal spin).

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt