508 zoekresultaten voor “early hominin” in de Publieke website
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Verplichte Matching
Voor Natuurkunde is de matchingsactiviteit een verplicht onderdeel van de toelatingsprocedure voor studenten met een Nederlandse vooropleiding.
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2 PhD - NWO OC-L project IMAGES ON THE MOVE
Geesteswetenschappen, Centre for the Arts in Society
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Judith Pollmann bij Het verhaal van Nederland
In de zesde aflevering van de televisieserie ‘Het verhaal van Nederland’ laat hoogleraar Judith Pollmann haar licht schijnen over de strijd tussen ‘geuzen’ en ‘papen’.
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PROGENY
How do you make a technology sustainable that does not even exist yet? Well, by bringing together an interdisciplinary team of pioneering European experts right at the start and paying attention to sustainability right from the development phase.
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Canonical Cultures network
Religion, Philosophy, and the Pre-modern World
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Deadlines voor aanmelden
Meld je op tijd aan!
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Unfolding the regulation of stress response pathways upon liver injury
Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.
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Magnetic resonance force microscopy for condensed matter
In this thesis, we show how MRFM can usefully contribute to the field of condensed-matter.
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Pharmacogenomics in drug development: implementation and application of PKPD model based approaches
Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh
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Spinning worlds
Promotor: I. A. G. Snellen, Co-promotor: M. A. Kenworthy
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Small changes for long term impact: optimization of structure kinetic properties: a case of CCR2 antagonists
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman
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Breaking the witches' spell: towards steering the soil microbiome for volatile-mediated control of the root parasitic weed Striga
Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.
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Onderzoekschool Mediëvistiek
In de landelijke Onderzoekschool Mediëvistiek werken onderzoekers op het gebied van de Middeleeuwen van zes Nederlandse universiteiten samen. De school verzorgt (in samenwerking met de lokale graduate schools van de universiteiten) de opleiding tot mediëvistisch onderzoeker en biedt ook opleidingsactiviteiten…
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Zebrafish xenograft model: identification of novel mechanisms driving prostate cancer metastasis
Prostate cancer (PCa) is one of the most prevalent cancer in males.
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Business incubators: the impact of their support
A New Technology-Based Firm (NTBF) is a significant enabler of job creation and a driver of the economy through stimulating innovation.
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Materials Innovative Technologies Assessment (MIN-TEA)
How can prospective LCA be streamlined in a way that its practical application in research and technology development increases?
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Seeing voices: the role of multimodal cues in vocal learning
Humans and songbirds learn their vocalizations early in life by exposure to the vocalizations of adult conspecifics. Often, better learning outcomes are achieved with live, social, tutors than with audio-only exposure to vocalizations.
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Targeting the adenosinergic system
Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).
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Integrative taxonomy of araneomorph spiders: Breathing new life into an old science
Taxonomy as a science has accumulated data and knowledge for more than 250 years.
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Aspecten van Joods leven in Roermond en Midden-Limburg 1275-2018
Op 28 oktober 2021 verdedigde Hein van der Bruggen zijn proefschrift en behaalde daarmee de doctorstitel.
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Biophysical characterization of membrane protein-small molecule interactions
Promotor: Prof.dr. M. Ubbink
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Digging for data: the rise and fall of a Miocene mammal biodiversity hotspot in the Vallès-Penedès (Catalonia, Spain)
The Vallesian, 11.1-9 Ma, was a special time in the Vallès-Penedes basin near Barcelona, where a biodiversity hotspot existed. Europe had a subtropical climate, with rhinos, forest giraffes, lions, hyenas, flying squirrels and primates.
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Systems pharmacokinetic models to the prediction of local CNS drug concentrations in human
Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.
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Electrochemical and surface studies of the effect of naphthalene-based additives on tin electrodeposition
Tin electrodeposition applications have rapidly evolved in the past 25 years.
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Multiple star formation: chemistry, physics and coevality
Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.
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Lithium-ion batteries and the transition to electric vehicles
The transition to electric vehicles (EVs) reduces vehicle emissions to combat climate change. EVs raise concerns regarding the production of lithium-ion batteries and related emissions; while batteries can also provide energy storage services for the electricity system.
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Pharmacogenomics in Drug Development: Implementation and Application of PKPD Model Based Approaches
Model based approaches, integrating physiological parameters or linking exposure with response, are powerful tools to quantify and evaluate the impact of genetic differences that are reflected as variability of drug exposure and/or clinical response(s). This thesis “Pharmacogenomics in Drug Development: …
- Publicatie rond Engels op de pabo
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Community & Communicatie
De werkgroep community & communicatie fungeert als koepel die – naast de eigen activiteiten – met alle drie de werkgroepen werkt aan de community- en communicatiegerelateerde aspecten van hun activiteiten
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Strategies for braiding and ground state preparation in digital quantum hardware
With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.
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Some case studies of random walks in dynamic random environments
Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.
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Systems pharmacology of the amyloid cascade
According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).
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Cross-border Claims to Cultural Objects
Op 11 november 2021 verdedigde Evelien Campfens het proefschrift 'Cross-border Claims to Cultural Objects'. Het promotieonderzoek is begeleid door prof.dr. N.J. Schrijver en prof.dr. W.J. Veraart (VU Amsterdam).
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Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
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Empirical Legal Studies Leiden
Empirical Legal Studies in Leiden focust op het bouwen van een interdisciplinaire gemeenschap van rechtsgeleerden en sociale wetenschappers die samen juridische vraagstukken onderzoeken op het snijpunt van recht en gedrag, waarbij diverse soorten methoden worden gebruikt.
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The LeiCNS-PK3.0 model development and applications: healthy-to-diseased CNS pharmacokinetic translation
Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…
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Regulating Relations: Controlling Sex and Marriage in the Early Modern Dutch Empire
Promotie
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Protective Interventions by Local Elites in the Countryside of Early Islamic Egypt
Promotie
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Evaluating the microcirculation in early phase clinical trials: novel methodologies and interventions
Promotie
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Wetenschaps- en onderwijsbeleid
De YAL laat zich horen over beleidskwesties.
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Distant star formation in the faint radio sky
One of the key quests in astronomy is to study the growth and evolution of galaxies across cosmic time. Radio observations provide a powerful means of studying the formation of stars and subsequent buildup of distant galaxies, in a way that is unbiased by the presence of dust.
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Bibliotheek en LU-Card
Als alumnus van de Universiteit Leiden kunt u uw hele leven lang gebruik blijven maken van de Universitaire Bibliotheken Leiden (UBL).
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Probing new physics in the laboratory and in space
The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles.
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Organisatie
De Young Academy Leiden heeft een bestuur bestaande uit een voorzitter en een vicevoorzitter. Daarnaast wordt de YAL ondersteund door een projectmanager en een student-assistent.
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Evolutionary Developmental Biology of Bitterling Fish
We developed the bitterling as a unique, well-studied model organism in the area of the evolutionary ecology of brood parasitism. The bitterling-mussel relationship, interspecific mussel host preference, and mussel gill structure are studied in detail, to help understand the developmental adaptation…
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Towards a single-molecule FRET study of Frauenfelder's nonexponential rebinding of CO in myoglobin
Early time-resolved experiments by Frauenfelder on the ensemble of the kinetic rebinding of CO to myoglobin molecules resulted in a stretched exponential relaxa-tion due to a very large spread of the reaction rates of individual molecules.
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Resolving the building blocks of galaxies in space and time
We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.
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Data Centres for Natural Recources and Products
Creating information portals for support of European environmental policy.
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Corpora Non Agunt Nisi Fixata: Ligand Receptor Binding Kinetics in G Protein-Coupled Receptors
The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska