597 zoekresultaten voor “gene theory” in de Publieke website
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Counting problems for number rings
Promotor: H.W. Lenstra
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On the amount of sieving in factorization methods
Promotoren: R. Tijdeman, A.K. Lenstra, Co-promotor: H.J.J. te Riele
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Imperfect information variants of combinatorial games
Combinatorial games are games for two competing players, moving in a turn-by-turn fashion, in which there is no chance nor hidden information. Chess, checkers and the simpler tic tac toe are well-known examples of this class of games, as well as game of go.
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Shape Analysis for Phenotype Characterisation from High-throughput Imaging
We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska
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Exploring the chemical space of post-translationally modified peptides in Streptomyces with machine learning
The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.
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Spatial populations with seed-bank
In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…
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Compressed Σ-Protocol Theory
Promotie
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Extension of Operators on Pre-Riesz Spaces
This thesis mainly extends the theory of positive operators on Riesz spaces to a setting of pre-Riesz spaces.
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Deformations of nodal surfaces
Promotores: P. Stevenhagen, L. van Geemen Co-promotor: R.M. van Luijk
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On cluster algebras and topological string theory
Promotie
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Attachment Theory and Culture: Parenting in Latin America and rural Peru from an Attachment Theory perspective
Promotie
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Targeting tumors using T-cell receptor gene transfer
Promotie
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Dual Complexes of Semistable Varieties
This thesis is comprised of three chapters covering the theme of studying semistable varieties by looking at their dual combinatorial objects.
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Topics in mathematical and applied statistics
Promotor: A.W. van der Vaart
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Leiden SPSS project
Data theory research on the analysis on the multidimensional data
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Diophantine equations in positive characteristic
In this thesis three different topics in number theory are studied.
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Aspects of cosmic acceleration
The focus of the dissertation
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Fuzzy systems and unsupervised computing: exploration of applications in biology
In this thesis we will explore the use of fuzzy systems theory for applications in bioinformatics.
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Nurbolat Kenbayev
Wiskunde en Natuurwetenschappen
n.kenbayev@liacs.leidenuniv.nl | +31 71 527 2727
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Francesco Ragazzi
Faculteit der Sociale Wetenschappen
f.ragazzi@fsw.leidenuniv.nl | +31 71 527 2727
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Francesco Buda
Wiskunde en Natuurwetenschappen
f.buda@lic.leidenuniv.nl | +31 71 527 5723
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OSINT: From Theory, Intelligence to Evidence
Congres/symposium
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Insights from modeling metabolism and amoeboid cell motility in the immune system
This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.
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CRISPR Cas-induced targeted mutagenesis with Agrobacterium mediated protein delivery
The RNA guided endonuclease based on the CRISPR/Cas system of Streptococcus pyogenus is a potent new tool for genome engineering in plants.
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Responding to environmental cues: the adaptive qualities of chromatin compaction proteins
Promotor: M. Ubbink, Co-Promotor: R. T. Dame
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The development of molecular tools for investigating NAD+ metabolism and signalling
Nicotinamide adenine dinucleotide (NAD+) is the substrate used for the introduction of the ubiquitous and highly dynamic PTM in which either one or multiple adenosine diphosphate ribose (ADPr) moieties are covalently attached to a nucleophilic side chain of an specific amino acid in the target protein…
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Postdoc in Structures and Homotopy in Optimisation
Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)
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Temperature effects on genetic and physiological regulation of adaptive plasticity
Promotor: P.M. Brakefield
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Kummer theory for commutative algebraic groups
Promotie
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Exposed to events that never happen: Genaralized unsafety and prolonged psysiological stress responses
The aims of the project are to: further clarify 'inhibition by safety'; explore and describe all possible sagety factors, with a special focus on the primary human safety source: social connectedness; reviewing prolonged stress responses without stressors.
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Coherent dynamics in solar energy transduction
Promotor: Prof.dr. H.J.M. de Groot, Co-promotor: Francesco Buda
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ALGANT
Fundamental research in the ALgebra, Geometry And Number Theory
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Postmaterialism and Socioeconomic Status Impact in the Chilean Voting Behavior
This paper describes the development process of voting behavior in Chile; particularly the relationship between the class voting theory and the theory of cultural post-materialist vote is investigated. This research deals with Chile as a case study, a developing country with a relatively stable democracy…
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Basis reduction for layered lattices
Promotor: H.W. Lenstra
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Fermions and Bosons: Excitons in strongly correlated materials
Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp
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Refined tautological relations on moduli spaces of curves
The key purpose of this project is to study tautological relations on the level of closed differential forms or even integral cochains (i.e. we don't take classes in cohomology).
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Ab initio molecular dynamics calculations on reactions of molecules with metal surfaces
Promotor: Prof.dr. G.J. Kroes
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Targeting for success: Mechanistic insights into microRNA-based gene therapy for Huntington disease
Promotie
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Analysis of the angucycline biosynthetic gene cluster in Streptomyces sp. QL37 and implications for lugdunomycin production
Promotie
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Approach to Markov Operators on Spaces of Measures by means of equicontinuity
The subject of this thesis, ‘Approach to Markov Operators on Spaces of Measures by Means of Equicontinuity’, combines an analytical and probabilistic approach to Markov operators.
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Groups and fields in arithmetic
Promotor: Prof.dr. H.W. Lenstra
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Withstanding the cold: energy feedback in simulations of galaxies that include a cold interstellar medium
Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…
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Enhanced coinduction
Promotores: Prof.dr. F.S. de Boer, Prof.dr. J.J.M.M. Rutten (Radboud Universiteit Nijmegen)
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Automata-theoretic protocol programming
Promotor: F. Arbab
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Stochastic and Deterministic Algorithms for Continuous Black-Box Optimization
Continuous optimization is never easy: the exact solution is always a luxury demand and the theory of it is not always analytical and elegant.
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Cognitive Bias in the Judgment of Business Valuations and Valuators
Op 1 april 2020 verdedigde Marc Broekema zijn proefschrift 'Cognitive Bias in the Judgment of Business Valuations and Valuators'. Het promotieonderzoek is begeleid door promotor prof. dr. J.I. van der Rest.
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Bad reduction of Hilbert modular varieties with parahoric level structure
Promotor: S.J. Edixhoven, A. Iovita
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Complex multiplication constructions of abelian extensions of quartic fields
In this thesis, we show that we can use Shimura’s CM theory to explicitly compute the Hilbert class field of any primitive quartic CM field.