739 zoekresultaten voor “molecular theology” in de Publieke website
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Morphogenesis and protein production in Aspergillus niger
Promotores: C.A.M.J.J. van den Hondel, V. Meyer, Co-promotor: A.F.J. Ram
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A bioorthogonal chemistry approach to the study of biomolecules in their ultrastructural cellular context
In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.
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Identification of Therapeutic Targets and Antisense Oligonucleotide Mediated Exon Skipping Based Therapies in Arthritis
Promotor: G.J.B. van Ommen
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The Chara plasma membrane system : an ancestral model for plasma membrane transport in plant cells
Multicellular giant algae Chara species have been widely used in physiological studies for decades.
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Vervolgopleidingen
Na het afronden van de bacheloropleiding volgen verreweg de meeste studenten de masteropleiding.
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Accelerating the Photocatalytic Water Splitting in Catalyst−Dye Complexes
As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.
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Probing Molecular Layers with Low-Energy Electrons
Promotie
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Expanding the chemical space of antibiotics produced by Paenibacillus and Streptomyces
Antibiotic-resistant bacteria pose a major health threat. Addressing this challenge requires among others the development of new antibacterial compounds. The research described in this thesis focuses on discovering novel antibiotics from soil bacteria, specifically Streptomyces and Paenibacillus.Despite…
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Development of an Adverse Outcome Pathway (AOP) for metallic nanoparticles
What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?
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Benodigde documenten
Om je aan te melden voor de bacheloropleiding Molecular Science and Technology heb je meerdere documenten nodig. Zorg ervoor dat je deze documenten bij de hand hebt.
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Evolution of Molecular Resistance to Snake Venom α-Neurotoxins in Vertebrates
Promotie
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Drug-target residence time: a case for the adenosine A1 and A2A receptors
Promotor: A.P.IJzerman, Co-Promotor: L.H. Heitman
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Topological decoding of biomolecular fold complexity
Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…
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Synthetic peptides as tools in chemical immunology
This thesis has described novel synthetic methods to produce a variety of (glyco)peptides and their application in the study of various immunological processes.
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Control of Western flower thrips through jasmonate-triggered plant immunity
We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.
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Systematics and Biogeography of the Dissochaeta alliance (Melastomataceae)
Dissochaeta Blume (Melastomataceae, tribe Dissochaeteae) is well-known as a scrambling plant genus found in Southeast Asia, where it is an inhabitant of the tropical rainforests or evergreen forests.
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Mechanism-based inhibitors and probes for neuraminidases
Neuraminidases are enzymes that cleave glycosidic linkages of sialic acid. These enzymes are involved in influenza infections as well as in many cellular processes in mammals and micro-organisms.
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Evolutionary diversification of Nepenthes (Nepenthaceae)
Promotor: Erik F. Smets, Co-promotores: Barbara Gravendeel, Niels Raes
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Natural and non-natural factors influencing Alzheimer´s Aβ
Promotor: Prof.dr. J.P. Abrahams
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Proefstuderen LST
Studievoorlichting
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PhD Positions (Notre Dame)
The Graduate School at the University of Notre Dame accepts up to two, funded (tuition scholarship + full stipend) PhD students per year in Liturgical Studies. The program integrates three sub-disciplines: Liturgical History; Liturgical Theology; Ritual Studies. Deadline: 2 January 2023.
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Vacancy postdoc (Oslo)
The University of Oslo offers two three-year postdoctoral positions: one with a background in early medieval liturgy and the other in early medieval cultures of healing. The successful applicants will join the MINiTEXTS research group at the department (up to 10 group members) with regular activities,…
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Vacancy PhD (Oslo)
The University of Oslo offers two three-year PhD positions with focus on specific early medieval Latin textual additions. The successful applicants will join the MINiTEXTS research group at the department (up to 10 group members) with regular activities, internal seminars, workshops, and conferences.…
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Vacancy senior researcher (Oslo)
The University of Oslo offers a two-year senior researcher position with focus on early medieval Latin additions with musical notation. The successful applicants will join the MINiTEXTS research group at the department (up to 10 group members) with regular activities, internal seminars, workshops, and…
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Molecular sensors for calcium ion detection via triplet-triplet annihilation upconversion
Promotie
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Towards Photocatalytic Water Splitting in Homogeneous Solutions Using Molecular Metalloporphyrin Photosensitizers and Catalysts
Promotie
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Molecular imaging of pancreatic and rectal cancer - Towards optimized detection and response prediction
Promotie
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Elucidation of the molecular alterations underlying aging-associated muscle wasting by applying multi-omics
Promotie
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Decoding the molecular makeup of the human ovary through single-cell transcriptomics
Promotie
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The development of molecular tools for investigating NAD+ metabolism and signalling
Promotie
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Convergent molecular evolution of toxins in the venom of advanced snakes (Colubroidea)
Promotie
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The dust and molecular gas in the torus of NGC 1068
Promotie
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Molecular precision Surgery: technical innovations and their relation to interactive perception
Promotie
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Synthetic peptides, nucleic acids and molecular probes to study ADP- ribosylation
Promotie
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Ziektes detecteren met moleculen in het lichaam
Is het mogelijk om ziektes te diagnosticeren met behulp van moleculaire schakelaars? Over die vraag buigt het nieuwe internationale consortium LogicLab zich. Vanuit Leiden zijn scheikundige Sylvestre Bonnet en farmacoloog Thomas Hankemeier betrokken. Het project loopt voor vier jaar en krijgt ruim 3,5…
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Verplichte matching
Voor Molecular Science and Technology is de matchingsactiviteit een verplicht onderdeel van de inschrijving.
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Nanodeeltjes – redox eiwit biohybriden
Kunstmatige fotosynthese heeft als doel om via chemische processen zonne-energie om te zettn in brandstof. Semi-kunstmatige fotosynthese is een hybride aanpak waarbij chemische maar ook biotechnologische processen worden gebruikt. Wij hebben als doel om een hybride systeem te ontwikkelen met behulp…
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Studeren aan de Universiteit Leiden
Wil jij de beste redenen weten waarom je aan de Universiteit Leiden moet studeren? Of hoe het is om te leven in studentensteden zoals Leiden of Den Haag? Onze studenten vertellen je over hun studie aan de Universiteit Leiden.
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Studeren aan de Universiteit Leiden
Wil jij de beste redenen weten waarom je aan de Universiteit Leiden moet studeren? Of hoe het is om te leven in studentensteden zoals Leiden of Den Haag? Onze studenten vertellen je over hun studie aan de Universiteit Leiden.
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Integrating cellular and tissue dynamics with cell fate decisions through computational modeling
There is a need for alternative methods to replace, reduce and refine (3R) animal experimentation. Combining experimental data from high-throughput in vitro studies with in silico modeling is a promising approach to unravel the effect of chemicals on living cells and to gain a better understanding of…
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Chemical biology of glucosylceramide metabolism fundamental studies and applications for Gaucher disease
This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).
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Ginsenosides as selective glucocorticoid drugs: agonists, antagonists, and prodrugs
Glucocorticoids are potent anti-inflammatory drugs widely used clinically to treat various inflammatory and immune conditions. However, two main clinical problems limit their use. GCs trigger severe side effects and they induce acquired glucocorticoid resistance, especially during chronic systemic treatment…
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Linking simple molecules to grain evolution across planet-forming disks
Planets are formed in disks of gas and dust around young stars.
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Targeting the adenosinergic system
Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).
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The structure of the cytochrome P450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography
Promotor: Prof.dr. M. Ubbink
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Graphene at fluidic interfaces
In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…
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Computational, biochemical, and NMR-driven structural studies on histone variant H2A.B
Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.
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The ins and outs of ligand binding to CCR2
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman
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Exploring strange new worlds with high-dispersion spectroscopy
Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…
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The role of water in hydrogen electrocatalysis
Promotor: M.T.M. Koper, Co-promotor: L. Juurlink