Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.

The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…

Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…

This thesis investigates the contribution of quantum computers to machine learning, a field called Quantum Machine Learning. Quantum Machine Learning promises innovative perspectives and methods for solving complex problems in machine learning, leveraging the unique capabilities of quantum computers…

Computational thinking, programming, and algorithms form the basic of many of the things that are shaping our world, the way we work, interact, organize ourselves, and even spend our free time with social networks, streaming media, and games. And this transformation is far from being complete, it is…

Promotie

Lezing

A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.

Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

A management strategy has been developed for field margins to reduce pesticide drift to non-target areas and to promote biodiversity on arable land. To this end, 3 and 6 m wide strips along the edges of winter wheat, sugar beet and potato crops have been left unsprayed with herbicides and insecticides…

Het Institute of Security and Global Affairs (ISGA) biedt onderwijsprogramma’s aan op bachelor- en masterniveau. Tevens zijn er minoren, wordt er online onderwijs aangeboden en is er onderwijs voor professionals.

The work in this thesis demonstrates how to obtain an atomic-scale picture of a diverse set of complex surface structures observed using STM, under disparate conditions.

In this thesis, we developed new ways to use a technique called electroextraction (EE) to extract charged molecules from one liquid into another using an electric field.

Lezing

Jongeren nemen vaker risico dan kinderen en volwassenen. Dat komt doordat het beloningscentrum in hun hersenen veel actiever is als ze een beloning krijgen, ontdekte promovenda Barbara Braams. Daarnaast spelen persoonlijkheid, testosteron en sociale context een rol.

Promotie

Sociale Wetenschappen, Politieke Wetenschap

On 30 October 2020, Dr Mark Noort successfully defended his PhD investigation at the London School of Economics and political science (LSE) into

We are very excited to announce our Sustainability Series for 2023-2024. Each month an interactive workshop will be organised that discusses a specific theme of sustainability. Interested about sustainability? Do not hesitate to sign up to our events !

Faciliteiten waar LIBC leden gebruik van kunnen maken (in het Engels):

Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh

Promotor: Prof.dr. J.N. Kok, Co-Promotor: W.A. Kosters

In multi/many-core System-on-Chips (SoCs), the performance is almost linearly scaling with the number of processing elements.

Promotor: V. Vitelli, Co-promotor: J. Paulose

The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

To study how planetary systems come into existence we study much younger systems still in formation.

This thesis is about augmented reality (AR). AR is commonly considered a technology that integrates virtual images into a user’s view of the real world.

Promotor: W. Jaffe, Co-promotor: K. Meisenheimer

In dit project gebruiken we sociale netwerkanalyse om het gedrag van gebruikers op online fora en bijbehorende marktplaatsen in de tijd te analyseren.

Promotor: J.W.M. Frenken

Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: V. Vitelli

Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen

Het doel van het RAISE Onderzoek is om te onderzoeken hoe veerkrachtige mensen omgaan met stress. We kijken specifiek naar hoe belangrijke biologische systemen, zoals de HPA-as en het immuunsysteem, samenwerken met de hersenen en de sociale omgeving om veerkrachtig functioneren na moeilijkheden in de…

Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros

We consider the propagation of electrical signals through nerve fibres.

This work describes the use of click-to-release chemistry to get spatiotemporal control over immunocytokine activity. Until now, immunocytokines (cytokines coupled to a tumor-targeting-moiety) remained active throughout the body, being able to bind their respective receptors, causing mild to severe…

The research aims to explore the evolutionary adaptability of enzymes and the impact of temperature on protein evolution pathways, using M. tuberculosis β-lactamase BlaC as the object of study. Enzymes inherently embody a delicate balance between activity and stability, and the acquisition of new enzymatic…

Elk jaar reikt het Leids Universitair Studentenplatform (LUS) de Leidse Onderwijsprijs uit.

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

This thesis studies the geometry of representation varieties and character stacks. These are spaces parametrizing the representations of a finitely generated group, typically the fundamental group of a compact manifold, into an algebraic group G.

Bij eLaw verzorgen we een aantal vakken voor de master Jeugdrecht en voor de master International Children's Rights (Advanced LL.M.)