841 zoekresultaten voor “stam cell biology” in de Publieke website
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Hybrid zone dynamics in amphibians
Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.
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Innovating Cell Pharmacy with stem cells
Lezing, NGL-lezing
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Tenosynovial Giant Cell Tumours
Promotie
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Gold nanoparticle-peptide conjugates for biomedical applications
Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.
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Hans de IonghWiskunde en Natuurwetenschappen
h.h.de.iongh@umail.leidenuniv.nl | +31 71 527 7461
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Inhibitors and probes targeting mannanases
This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…
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RNA splicing in breast cancer progression
In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.
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Develop a methodology for assessing the effective dose of nanomaterials for environmental risk assessment purposes
How to make a quantitative assessment of the relative contribution to toxicity of ions and particles? Is the toxicity of nanoparticles related to their size or shape? Which physicochemical property of nanoparticles is an appropriate dose metric of nanoparticles?
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Meet Biology Leiden
Studievoorlichting
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Meet Biology Leiden
Studievoorlichting
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Growth-induced self-organization in bacterial colonies
Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.
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Physics implications of shape on biological function
Shape and biological function are tightly connected. Physical descriptions are used to connect the shape of a biological system with its function.
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Evolutionary molecular dynamics
This thesis introduces the concept of
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Vervolgopleidingen
Na het afronden van de bacheloropleiding volgen verreweg de meeste studenten de masteropleiding.
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Unravelling cell fate decisions through single cell methods and mathematical models
Promotie
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
- Biology MSc diploma uitreiking
- MSc Biology diploma ceremonies
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Systems microscopy to unravel cellular stress response signalling in drug induced liver injury
Promotor: B. van de Water
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Sensing Transport
Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.
- Afstudeerceremonie MSc Biology
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Afstudeerceremonie MSc Biology
Afstudeerceremonie
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Afstudeerceremonie MSc Biology
Afstudeerceremonie
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Graduation Ceremony MSc Biology
Festival
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The impact of one: single cell analysis of T cell states in human cancer
Promotie
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of metabolic pathways and sensors in regulation of dendritic cell- driven T cell responses
Promotie
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TCRs as Precision Tools against B-cell and Plasma Cell Malignancies
Promotie
- Afstudeerceremonie MSc Biology
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Learning cell identities and (post)-transcriptional regulation using single- cell data
Promotie
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Contact
Neem contact op met de afdeling Environmental Biology
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Taking control of charge transfer: strategic design for solar cells
Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda
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Multi-omics studies of the control of growth and antibiotic production of Streptomyces
Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).
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Over het programma
In 2020 zijn de stimuleringsprogramma's van de Universiteit Leiden gestart, met als één van de programma's regeneratieve geneeskunde.
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Composition and function of integrin adhesions
Integrins play an essential role in multicellular life by connecting cells to the extracellular matrix.
- Diploma-uitreiking master Biology
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Analysis of sub-visible particles in complex injectable formulations
Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik
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High throughput microscopy of mechanism-based reporters in druginduced liver injury
Promotor: B. van de Water
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Phase separation in lipid-based nanoparticles: exploring the nano-bio interface
This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.
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Projecten
Projecten van de afdeling Environmental Biology
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Onderwijs
Een uitgebreid overzicht van het onderwijs van de afdeling Environmental Biology is beschikbaar op de Engelse versie van de CML-website
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Publicaties
Een uitgebreid overzicht van de publicaties van de afdeling Environmental Biology is beschikbaar op de Engelse versie van de CML-website
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Onderzoek
Een uitgebreid overzicht van het onderzoek van de afdeling Environmental Biology is beschikbaar op de Engelse versie van de CML-website
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Lan DupuisWiskunde en Natuurwetenschappen
l.dupuis@cml.leidenuniv.nl | +31 71 527 2727
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Emily StrangeWiskunde en Natuurwetenschappen
e.f.strange@cml.leidenuniv.nl | +31 71 527 2727
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Single-cell immune profiling of atherosclerosis
Promotie
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Red cell transfusion in critically ill patients
Promotie
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How costimulation directs regulatory T cell responses
Promotie
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Essays on Welfare Benefits, Employment, and Crime
Op 20 januari 2022 verdedigde Marco Stam het proefschrift 'Essays on Welfare Benefits, Employment, and Crime'. Het promotieonderzoek is begeleid door prof.dr. M.G. Knoef.
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Imaging of alkyne-functionalized ruthenium complexes for photoactivated chemotherapy
In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.
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The role of autophagy during carbon starvation in Aspergillus niger
Autopaghy is an intracellular degradation system which targets cytosolic components to lytic compartments for degradation and recycling of the building blocks of the cell.