416 zoekresultaten voor “cognitie formation” in de Publieke website
-
The environmentally-regulated interplay between local three- dimensional chromatin architecture and gene expression
Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.
-
Involvement of host and bacterial factors in Agrobacterium-mediated transformation
Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.
-
Immunity in atherosclerosis: novel assays, biomarkers and therapeutic approaches
Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.
-
The Role of Linker DNA in Chromatin Fibers
The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.
-
Modelling the interactions of advanced micro- and nanoparticles with novel entities
Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.
-
Systems pharmacology of the amyloid cascade
According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).
-
Mechanistic studies of the water oxidation reaction with molecular iron catalysts
In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.
-
The shell evolution of the Hydrocenidae of Malaysian Borneo
The thesis is about the study of shell evolution of the Hydrocenidae of the genus Georissa. This thesis started with a general overview on the evolutionary process of animals due to ecological changes.
-
Visualizing strongly-correlated electrons with a novel scanning tunneling microscope
Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.
-
Fundamental research on the voltammetry of polycrystalline gold
Voltammetry plays a crucial role in modern scientific research by offering valuable insights into the electrochemical properties of materials, with wide-ranging applications in fields such as materials science, energy storage, corrosion studies, and sensor development.
-
Chemical reactivity of O2, CO and CO2 on Cu surfaces
Despite the history of studies on methanol formation from CO2, the dominant elementary reaction steps that constitute the chemical mechanism for this catalyzed process are not determined.
-
Resolving gas-phase metallicity in galaxies
Galaxies are environments where gas coalesces, cools, and is converted into stars. However, it remains unclear the exact mechanisms through which galaxies acquire, redistribute and lose their gas.
-
Histone-DNA assemblies in archaea. Shaping the genome on the edge of life
All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).
-
Cognitive enhancement: Toward the integration of theory and practice
Cognitive enhancement is het gebruik van elke methode of techniek met als doel het verbeteren van cognitieve prestaties.
-
op: “The Circle of Life: from the beginning of the universe to the formation of life”
Lezing, Kaiser Lente Lezing
-
Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
-
Heterogenized molecular (pre)catalysts for water oxidation and oxygen reduction
Before the large scale use of renewable energy sources can be implemented in our society, the storage of electrical energy needs to be tackled. Storage the energy as hydrogen via the reduction of protons is a good option.
-
Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
-
The holographic glass bead game: from superconductivity to time machines
Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm
-
Photo-activation of ruthenium-decorated upconverting nanoparticles
Metal-based prodrugs based on ruthenium(II) polypyridyl complexes have proven to be very suitable for application in both photodynamic therapy (PDT) and photo-activated chemotherapy (PACT).
-
The galaxy–dark matter connection: a KiDS study
In this thesis, the research focuses on the properties of dark matter and dark matter haloes and how they connect with the galaxies we can observe in the Universe.
-
Redox Interconversion between Metal Thiolate and Disulfide Compounds
In the last decade, the redox interconversion between metal thiolate and disulfide compounds has been extensively investigated for copper, but not for other transition metal ions.
-
The assembly history of the milky way nuclear star cluster
Promotor: P. T. de Zeeuw, Co-promotor: N. Neumayer; G. van de Ven
-
Microscopy and Spectroscopy on Model Catalysts in Gas Environments
In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.
-
Lights in a sea of darkness: constraining the nature and properties of dark matter using the stellar kinematics in the centres of ultra-faint
Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.
-
Van woord tot akkoord. Een analyse van de partijkeuzes in CPB-doorrekeningen van verkiezingsprogramma's en regeerakkoorden, 1986-2017
This PhD-thesis analyses the relationship between the parties’ choices in the CPB Netherlands Bureau for Economic Policy Analysis’ assessments of the election manifestos and coalition agreements over the period 1986-2017, and tries to explain this relationship.
-
Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
-
A time-space translation mechanism for patterning the vertebrate anteroposterior axis
My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.
-
De verzamelwoede van Martinus van Marum (1750-1837) en de ouderdom van de aarde
Promotor: F.J. van Lunteren, E. Jorin
-
Multiscale mathematical biology of cell-extracellular matrix interactions during morphogenesis
During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.
-
Structure dependence of molecular reactions on surfaces
The research presented in this thesis makes use of small molecules (as H2 , D2 and O2 ) on well-defined single crystal surfaces (flat Pt(111), flat Cu(211) and curved Pt(111)) to elucidate the role of surface structure and degrees of freedom in the reactant in specific surface reactions.
-
Sterrewacht Leiden
Sterrewacht Leiden is het sterrenkundig instituut van de Faculteit der Wiskunde en Natuurwetenschappen van de Universiteit Leiden.
-
Cholesterol metabolism in mouse models of atherosclerosis and adrenal steroidogenesis
Cholesterol influences many pathways, including serving as precursor for adrenal steroidogenesis. Imbalance of cholesterol levels has been implicated in several diseases including cardiovascular diseases and its underlying pathology, atherosclerosis.
-
Novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).
-
Strategy Dynamics
In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.
-
Arabidopsis AGC3 kinases and PIN plasma membrane abundance
The plant hormone auxin plays a central role in the growth and development of plants. Auxin acts in a concentration dependent manner and polar cell-to-cell transport of this hormone determines its distribution in the tissues of plants. This polar auxin transport is mediated by several families of auxin…
-
Ellen de Bruijn
Faculteit der Sociale Wetenschappen
edebruijn@fsw.leidenuniv.nl | +31 71 527 3748
-
Autisme in het hoger onderwijs
Hoe kunnen we kwaliteit van leven en studiesucces vergroten bij jonge, hoog-functionerende volwassenen met autisme?
-
Onderzoek
In Navigatie Lab Leiden doen we onderzoek naar ruimtelijke cognitie. We volgen hierbij 3 thema’s: navigatievermogen, ruimtelijke vaardigheden, en nieuwe technieken
-
Stephan Raaijmakers: 'Mens en systeem moeten elkaar beter begrijpen'
Je kunt spraak-assistent Siri vragen naar het weer, maar een écht gesprek zit er nog niet in. Je kunt niet refereren aan iets wat je eerder zei, of vragen waarom het systeem iets zegt. Stephan Raaijmakers, bijzonder hoogleraar vanuit TNO, wil daar iets aan doen.
-
Minor Music Studies
Muziek als een veelzijdig en integraal onderdeel van onze samenleving.
-
Ineke van der Ham over landelijk publieksonderzoek 'Navigeren kun je leren'
'Er zijn amper verschillen in navigatievermogen tussen Nederlandse mannen en vrouwen', zegt de Leidse neurowetenschapper na een jaar publieksonderzoek samen met het Weekend van de Wetenschap onder ruim 13.000 deelnemers van 8-95 jaar. Het onderzoek is afgerond, gamen voor navigatietips is nog mogel…
-
Massieve sterren als fabriek voor de bouwstenen van het leven
NASA’s telescoop SOFIA geeft een nieuw kijkje in de chemie nabij jonge sterren: de geboorteplaats van nieuwe planeten. De Leidse promovendus Andrew Barr schrijft erover in de Astrophysical Journal. Hij en zijn collega’s vonden enorme hoeveelheden water en organische moleculen in de wervelende, schijfvormige…
-
Staatscommissies/State committees
In this project of the Center for Public Values & Ethics (CPVE) ongoing research is conducted on the history of advice to Dutch central government by so-called State committees from 1814 to 2014. State committees have been installed by Dutch central government since 1814 to provide expert advice, research…
-
Empathic or anxious mistakes?
A neurocognitive investigation of the development of social performance monitoring in youth growing up in stressful versus non-stressful environments
-
De illusie als sleutel: hoe ruimtelijke techniek patiënten kan helpen
Ruimtelijke techniek, zoals virtual reality, kan patiënten helpen die moeite hebben met ruimtelijke cognitie, bijvoorbeeld wanneer zij snel de weg kwijtraken. In haar oratie vertelt neuropsycholoog Ineke van der Ham over het belang van de patiëntbeleving, avatars en de ruimte voor innovatie.
-
Onderzoek
Het Instituut Psychologie verzorgt innovatief en interdisciplinair onderzoek en onderwijs binnen de psychologie en aanverwante vakgebieden. Daarbij ligt de focus op vier grote gebieden: Gezondheid en Welzijn; Ontwikkelen en Leren; Sociaal-cognitief-affectieve Besluitvorming; en Geavanceerde Gedragswetenschappelijke…
-
Onderzoek
Hoe verwerven mensen taal? Hoe kun je je brein trainen? Wat is het effect van stress op het brein van een ongeboren kind? LIBC-onderzoeksthema's variëren van psychiatrische stoornissen tot cognitieve robotica en van taalverwerking tot de impact van sociale factoren. Maak kennis met verschillende belangrijke…
-
Wat zien kinderen in kunst? Zo onderzoeken psychologen dat in het Rijksmuseum
Van games tot speurtochten: veel musea doen van alles voor kinderen. Maar hoe kijken kinderen werkelijk naar kunst? Raken schilderijen hen meer als de informatie speciaal op jonge bezoekers is afgestemd? Ga met psycholoog Francesco Walker mee naar het Rijksmuseum en kijk hoe zijn team dit met eyetrackers…
-
Towards artificial photosynthesis: resolving supramolecular packing of artificial antennae chromophores through a hybrid approach
Promotor: H.J.M. de Groot