Single-Molecule Microscopy (SMM) techniques constitute a group of powerful imaging tools that enable researchers to study the dynamic behavior of individual molecules.

This thesis is divided into two parts. In Part I we study metastability properties of queue-based random-access protocols for wireless networks. The network is modeledas a bipartite graph whose edges represent interference constraints. In Part II we study spectra of inhomogeneous Erdős-Rényi random…

In this thesis we study the moduli space of genus g curves, and the differential forms that occur naturally on this moduli space.

In this study the flows of PVC and its additives through the Swedish Society were followed from the cradle to the grave (from production to waste treatment).

Binnen dit instituut wordt veel gevangenisonderzoek verricht. Detentie is de strengste sanctie die in de strafrechtstelsels van de Europese landen wordt toegepast.

How does the management of Elephant Marsh Fishery in Malawi relate to wider contexts of policies, theories and regions? And how can the current management system be adapted to achieve long-term sustainability of the fishery?

Kennis van moslimsamenlevingen is onmisbaar om in een geglobaliseerde wereld te kunnen functioneren en om onze eigen Nederlandse maatschappij goed te begrijpen. In Leiden verdiepen onderzoekers zich in de talen, cultuur, religie, rechtssystemen en geschiedenis van moslimsamenlevingen en zetten daarmee…

In the first part of this thesis we study the geometry of folding patterns.

Promotor: Prof.dr. L.J. Slikkerveer

The largest genus within the Phyllanthaceae family is a group called Phyllanthus L. Recent studies have shown, that Phyllanthus is paraphyletic with the genera Glochidion, Breynia and Synostemon nested within it.

What invertebrates are available to feed nestlings in an agricultural landscape of varied complexity?

Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…

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Mechanical metamaterials are carefully engineered materials whose properties are controlled by their structure, not by their composition, which allows using metamaterials to study and control physical effects in detail⁠.

Promotor: Prof.dr. B.R. Katzy, Prof.dr. J. de Vries

In the early universe, the dynamics of the Higgs field can give rise to many interesting phenomena.

Promotor: Prof.dr. A.G.G.M. Tielens

This dissertation is an experimental study of laser-generated, atmospheric pressure, transient toroidal helium plasmas.

The focus of the dissertation

There are many interpretations of quantum mechanics, and ultimately experiments are needed to verify or falsify these interpretations.

Arithmetic geometry concerns the number-theoretic properties of geometric objects defined by polynomials. Mathematicians are interested in the rational solutions to these geometric objects.

Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.

Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.

The thesis is about the study of shell evolution of the Hydrocenidae of the genus Georissa. This thesis started with a general overview on the evolutionary process of animals due to ecological changes.

A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.

eLaw onderzoekt de rol van het recht in de informatiemaatschappij: hoe kan het recht bijdragen aan een goede werking van informatie- en communicatietechnologie, en het gebruik ervan door burgers, bedrijven en overheden?

Het Bachelor Honours Programme Sustainability is een uniek gezamenlijk initiatief van het LDE Centre for Sustainability en de Honours Academies van de Universiteit Leiden, de TU Delft en de Erasmus Universiteit Rotterdam (LDE Alliance).

The lipid membrane is a basic structural component of all living cells. Embedded in this nanometer-thin barrier, membrane proteins shape the membrane and at the same time respond to the shape of the membrane.

Promotor: M.T.M. Koper, Co-promotor: J.B.F. Juurlink

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

Promotor: S.M. Verduyn Lunel

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

Promotor: Prof.dr. G.P. van Wezel

Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…

Promotores: Prof.dr. F.S. de Boer, Prof.dr. J.J.M.M. Rutten (Radboud Universiteit Nijmegen)

Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.

Promotor: G.P. van Wezel, Co-promotor: D. Claessen

Het onderzoek van eLaw sluit vooral (maar niet uitsluitend) aan bij het facultaire onderzoeksprogramma Effective Protection of Fundamental Rights in a Pluralist World. De centrale onderzoeksvraag van dit programma is: welke kansen en bedreigingen vloeien voort uit de institutionele en normatieve diversiteit…

Promotor: J. N. Kok, Co-promotor: A. J. Knobbe

Tin electrodeposition applications have rapidly evolved in the past 25 years.

This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.

Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.

Promotor: P.D. Grünwald

The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).

Synthetic microswimmers take an important place within the interdisciplinary field of active soft matter.

Promotor: Prof.dr. T. Hankemeier, Prof.dr. J.C.T. Eijkel (Twente University)

Op 21 oktober 2021 verdedigde Frederik Behre het proefschrift 'A European Ministry of Finance?'. Het promotieonderzoek is begeleid door promotor prof.dr. S.C.G. Van den Bogaert.

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.

Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).