1,113 zoekresultaten voor “james well since telescope” in de Publieke website
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Interactions from lipid membrane deformations
Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.
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Unraveling the mechanism of multicopper oxidases: from ensemble to single molecule
Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma
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Immunity in atherosclerosis: novel assays, biomarkers and therapeutic approaches
Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.
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Fertility and fontanels: women’s knowledge of medicinal plants for reproductive health and childcare in western Africa
Promotor: E.F. Smets, Co-promotor: T.R. van Andel
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Synthesis of Ribitol Phosphate based Wall Teichoic acids
Antibiotic resistance, caused by widespread use of antibiotics, leads to bacterial infections that are difficult, if not impossible, to treat and is a major worldwide health concern.
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Biomimetic Copper Catalysts for the Electrochemical Oxygen Reduction Reaction
Human civilization consumes a huge amount of fossil fuels, which has resulted in an atmospheric CO2 level which has not been higher in over 800 millennia.
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Some case studies of random walks in dynamic random environments
Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.
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Constraint-Based Analysis of Business Process Models
Business Process Model and Notation (BPMN) has become the standard for business processes diagrams.
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Impact of low-carbon electricity development on carbon emissions in China
Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.
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Structural changes in single chromatin fibers induced by tension and torsion
Promotor: T. Schmidt, Co-promotor: S. J.T. van Noort
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Biomimetic models of [NiFe] hydrogenase for electrocatalytic hydrogen evolution
The growing demand of energy indicates that global energy resources in the form of fossil fuels will not be sufficient in the future. In order to solve potential future energy problems development of a sustainable hydrogen economy is highly desirable.
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The endocannabinoid system in zebrafish larvae
In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.
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Cross-border Claims to Cultural Objects
Op 11 november 2021 verdedigde Evelien Campfens het proefschrift 'Cross-border Claims to Cultural Objects'. Het promotieonderzoek is begeleid door prof.dr. N.J. Schrijver en prof.dr. W.J. Veraart (VU Amsterdam).
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Tailoring x-ray tomography techniques for cultural heritage research
Visualizing the internal structure is a crucial step in acquiring knowledge about the origin, state, and composition of cultural heritage artifacts. Among the most powerful techniques for exposing the interior of cultural heritage objects is computed tomography (CT), a technique that computationally…
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Artificial metallo-proteins for photocatalytic water splitting: stability and activity in artificial photosynthesis
Climate change is one of the largest challenges faced by humanity. To combat this research into alternatives to fossil fuels is ongoing. Dihydrogen is considered a good alternative fuel, since its burning only forms water.
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Op zoek naar buitenaards leven: de zoektocht naar leefbare atmosferen buiten ons zonnestelsel
Zoeken naar atmosferen rondom planeten buiten ons zonnestelsel is zoeken naar buitenaards leven. Sterrenkundige Sebastian Zieba gebruikte data van de James Webb Space Telescope om kleine rotsachtige exoplaneten te bestuderen, maar vond nog geen buitenaardse wezens. Toch zijn zijn bevindingen erg interessant…
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The Gaia telescope: mapping 1 billion stars with 1 billion pixels
Lezing, Kaiser Lente Lezing
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Speuren naar gepolariseerd licht in zoektocht naar buitenaards leven
Een nieuwe manier om het licht van verre planeten te analyseren zou ons bewijs kunnen leveren van buitenaardse planten, schrijft astronomie-auteur Colin Stuart in de New Scientist. In zijn artikel beschrijft hij het werk van de groep van de Leidse astronoom Rob van Holstein. Dit team detecteerde afgelopen…
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Hoe de snelheidsduivels van het universum ons iets leren over de Melkweg
Met meer dan duizend kilometer per seconde razen ze voort: de allersnelste sterren in ons Melkwegstelsel. Promovendus Fraser Evans deed onderzoek naar deze ongrijpbare hypersnelle sterren en ontdekte dat ze ons veel kunnen leren over bijvoorbeeld zwarte gaten en supernova’s.
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Wat kleine isotopen ons vertellen over planeten buiten ons zonnestelsel
Planeten in andere zonnestelsels bevatten waardevolle informatie over het ontstaan van planeten en leven. Promovenda Yapeng Zhang heeft hun atmosferen bestudeerd door te kijken naar hun kleinste onderdelen: isotopen. Met haar onderzoek hoopt ze te ontdekken wat ons eigen zonnestelsel uniek maakt.
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Student schoont archiefdata op en onthult twee stellaire cocons
Tijdens het bestuderen van zestien jaar aan meetgegevens van jonge sterren ontdekte de Leidse masterstudent Sam de Regt dat twee van die sterren nog gehuld waren in geboortewolken. Nog niet eerder bracht iemand deze twee sterren zo scherp in beeld. Hij publiceert zijn opschoonmethode en de nieuwe afbeeldingen…
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“All the aids which a beginner needs”: James Summers’ (1828-1891) research on Chinese grammar
Promotie
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Kluitersprijs voor excellente studenten Minor Intelligence Studies 2021- 2022
De 'Kluitersprijs' wordt jaarlijks uitgereikt aan studenten die excellente resultaten behalen in de minor Intelligence Studies.
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Hoe herken je de atmosfeer van buitenaardse lavawerelden?
In de afgelopen 30 jaar zijn er ruim 5000 planeten ontdekt buiten ons zonnestelsel. Een veelvoorkomende exoplaneet is de lavawereld, een hete superaarde met oceanen van vloeibaar lava. Mantas Zilinskas ontwikkelde modellen om mogelijke atmosferen daarvan te simuleren. Die simulaties bieden houvast voor…
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NPO-middelen
Lees hier alles over de extra financiële middelen die de Rijksoverheid beschikbaar stelt vanuit het Nationaal Programma Onderwijs.
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Unfolding the regulation of stress response pathways upon liver injury
Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.
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Small scale kinematics of massive star-forming cores
Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: M.R. Hogerheijde
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Knowledge Extraction from Archives of Natural History Collections
Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.
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Dyslipidemia at the crossroad of the skin barrier and the arterial wall
The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…
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Convergent molecular evolution of toxins in the venom of advanced snakes (Colubroidea)
The explosive radiation and diversification of the advanced snakes (superfamily Colubroidea) was associated with changes in all aspects of the shared venom system. Morphological changes included the partitioning of the mixed ancestral glands into two discrete glands devoted for production of venom ormucous…
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Freedom of additional signals on genes: on the combination of DNA mechanics, genetics and translation speed
DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.
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Targeting the adenosinergic system
Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).
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Chemical functionalization of the graphene surface for electrical and electrochemical sensing application
Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.
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Algebraic filters for filtered backprojection
Promotor: K.J. Batenburg, Co-promotor: A.W. van der Vaart, B. de Smit
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Imperfect information variants of combinatorial games
Combinatorial games are games for two competing players, moving in a turn-by-turn fashion, in which there is no chance nor hidden information. Chess, checkers and the simpler tic tac toe are well-known examples of this class of games, as well as game of go.
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Geometry of Vegetation Pattern
One of the effects of climate change is the phenomenon of desertification, a process that occurs in semi-arid and arid areas and causes land degradation as well as vegetation loss. Due to the lack of resources, vegetation self-organizes to sustain itself by forming large-scale spatial patterns.
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Dormancy in stochastic interacting systems
Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.
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Applications for activity-based probes in biomedical research on glycosidases
Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.
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Innate immune modulation in atherosclerosis and vascular
Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax, Co-promotor: I. Bot
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Systems diagnosis in chronic disease: prediction and evaluation
Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen
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Bacterial glycomimetics: synthesis and applications
This work has described synthetic strategies towards well-defined structures resembling capsular polysaccharide (CPS) fragments, CPS mimics, teichoic acid (TA) fragments as well as a third-generation ring-closing tandem metathesis (RCM) linker to better exploit the potential of automated synthesis.
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Tuning in to star-planet interactions at radio wavelengths
Low-mass main-sequence stars like our Sun are continuous sources of outflowing hot magnetised plasma. In the case of the Sun, this is known as the solar wind, whereas for other stars they are called stellar winds.
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Protostellar jets and planet-forming disks: Witnessing the formation of Solar System analogues with interferometry
The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.
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Suppressing a Sea of Starlight: Enabling technology for the direct imaging of exoplanets
Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik
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Untangling cosmic collisions: a study of particle acceleration and magnetic fields in merging galaxy clusters
On the largest scale, the Universe resembles a cosmic spiderweb. Most galaxies coexist in small groups within the threads of this web. At the nodes of the threads are enormous groups of galaxies forming the largest structures in the universe still held together by gravity: clusters of galaxies.
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Early Dutch Radio Astronomy (1940-1970)
Promotores: F.H. van Lunteren, F.P. Israel
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Exploring the interactions of M dwarf winds and cosmic rays
This thesis focus on the interaction between M dwarf stellar winds and Galactic cosmic rays and the possible effects on the habitability of exoplanets.
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Cosmic particle acceleration by shocks and turbulence in merging galaxy clusters
In this thesis, I study the formation of large-scale structure and the physics of particle acceleration at large scales (~Mpc).
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Extremely loud & incredibly far: observing radio bright AGN into the cosmic dawn
In this thesis new methodologies are developed for the detection and systematic study of radio sources in the early universe. This allows us to gain a deeper understanding of the formation and evolution of galaxies, the activity of supermassive black holes, and the final phase transition of our universe:…
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Astronomen zien ster met stofschijf die nog steeds groeit
Een internationaal team van sterrenkundigen waaronder ook Leidse wetenschappers publiceert het beeld van een jonge ster met een omringende stofschijf die nog steeds gevoerd wordt vanuit de omgeving. Het verschijnsel rond de ster SU Aur kan verklaren waarom zoveel exoplaneten niet netjes uitgelijnd zijn…