In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

Cathodic corrosion is a relatively unknown phenomenon that can severely etch metallic electrodes at cathodic (negative) potentials.

Promotor: Prof.dr. S. Haring

The global agri-food system plays a critical role in food security and environmental issues.

This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…

In his dissertation Michiel Hooykaas outlines the results of six empirical research projects focused at biodiversity awareness in the Netherlands, specifically people’s knowledge about animals.

Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.

The key purpose of this project is to study tautological relations on the level of closed differential forms or even integral cochains (i.e. we don't take classes in cohomology).

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Promotor: K. Kuijken, Co-Promotor: H. Hoekstra

Promotor: K.J. Batenburg

The applications of studying the early development of insects range from agriculture to material science.

Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst

The Copenhagen interpretation of quantum mechanics states that a measurement collapses a wavefunction onto an eigenstate of the corresponding measurement operator.

It is an established fact that the Standard Model has to be extended to explain the so-called Beyond the Standard Model (BSM) phenomena: dark matter, matter-antimatter asymmetry of the Universe and neutrino flavour oscillations.

Promotores: T.H. Oosterkamp, N. de Jonge

Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

Op 23 februari 2022 verdedigde Cale Davis het proefschrift 'Prosecutorial Discretion in International Criminal Justice'. Het promotieonderzoek is begeleid door prof.dr. C. Stahn en dr. J.C. Powderly.

This thesis considers multi-prover commitment schemes whose security is based on restrictions on the communication between the provers.

Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort

Women Writing Mexico (WWM) is a network of women and men concerned with the human rights crisis in Mexico and more specifically, with the impact of structural forms of poverty, everyday violence, and discrimination based on gender, race, social class, and ethnicity, that particularly have an impact…

Promotores: J. Kok, M. Chaudron (Chalmers University)

Exploring linkages between energy and material use and implications for sustainable development.

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

Development of GHG calculator for bio-electricity and heat.

Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm

The redox-conversion reaction of metal-disulfide and metal-thiolate complexes are important, as they may shed light on electron-transfer reactions that often occur in Nature.

Materials balances have been used in the recent past for the analysis of substance oriented environmental problems and the formulation of measures for environmental policy. In this study an integrated tool, based on the materials balance principle, has been developed for the analysis of both environmental…

Balsaminaceae is a diverse plant family characterized by a huge floral morphological diversity.

Electrons in a crystal lattice have properties that may differ from those of a free electron in vacuum.

Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet

Over the last three decades, the discovery of exoplanets has revealed the boundless variety of worlds beyond our own Solar System⁠. Majority of planetary systems contain short-period planets that are larger than Earth but smaller than Neptune⁠.

In het academisch jaar 2023-2024 biedt het interdisciplinaire onderzoeksprogramma Sociale Veerkracht en Veiligheid vier vakken aan voor studenten die beginnen met het derde jaar van hun bachelor. Deze vakken zijn te volgen binnen de ruimte voor keuzevakken. Je kunt de vakken afzonderlijk als keuzevak…

My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.

Modeling and analysis of cyber-physical systems are still challenging. One reason is that cyber-physical systems involve many different parts (cyber or physical), of different nature (discrete or continuous), and in constant interaction via sensing and actuating.

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

In this PhD-thesis several new and existing data science application are described that are particularly focused on applications for tax administrations.

The research provides insight into disease behavior in both rural and semi-urban areas in Serengeti in Tanzania.

This monograph focuses on clustering of objects in high-dimensional data, given the restriction that the objects do not cluster on all the attributes, not even on a single subset of attributes, but often on different subsets of attributes in the data.

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

We found that, next to the effectiveness of the intervention, it’s also very likely that the intervention is cost-effective compared to attention only.

Public Administration is a major refereed journal publishing articles on public administration, public policy and public management.

uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.

Examining the sustainability aspects of biotechnology, especially those related to the production of ethanol from biomass.

The Dutch atlas with pesticides concentrations in surface waters have been overhauled. This new, free accessible, website is in line with the European Framework Directive on Water (In Dutch: KRW).

Promotor: Prof.dr. E. Eliel, Co-Promotor: M.J.A. de Dood