2,512 zoekresultaten voor “state cell technology” in de Publieke website
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Sensing Transport
Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.
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Constraints on large-scale implementation of BioSolarCells, Early stage assessment of environmental value propositions
What performance criteria does a new technology have to fulfill in order to be added to the list of future energy options and what constraints exist in terms of broad market penetration?
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Over het programma
In 2020 zijn de stimuleringsprogramma's van de Universiteit Leiden gestart, met als één van de programma's regeneratieve geneeskunde.
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TCRs as Precision Tools against B-cell and Plasma Cell Malignancies
Promotie
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Learning cell identities and (post)-transcriptional regulation using single- cell data
Promotie
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of metabolic pathways and sensors in regulation of dendritic cell- driven T cell responses
Promotie
- Laboratory for Ceramics Studies
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Paul van TrigtFaculteit der Geesteswetenschappen
p.w.van.trigt@hum.leidenuniv.nl | 071 5271349
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Systems microscopy to unravel cellular stress response signalling in drug induced liver injury
Promotor: B. van de Water
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Composition and function of integrin adhesions
Integrins play an essential role in multicellular life by connecting cells to the extracellular matrix.
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Spatio-temporal aspects of antigen cross-presentation in dendritic cells: with click-to-release chemistry
The first steps are made in personalised cancer vaccination strategies, which aim to induce a more specific immune response with fewer side effects. The activation of cytotoxic T cells is crucial for an effective immune response.
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Analysis of sub-visible particles in complex injectable formulations
Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik
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Phase separation in lipid-based nanoparticles: exploring the nano-bio interface
This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.
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How costimulation directs regulatory T cell responses
Promotie
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Single-cell immune profiling of atherosclerosis
Promotie
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Red cell transfusion in critically ill patients
Promotie
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Feodor-Lynen onderzoeksbeurs voor Bela Bode
Dr. Bela Bode ontvangt van de Alexander von Humboldt-stichting de Feodor Lynen onderzoeksbeurs voor de ontwikkeling van nieuwe methoden voor verbetering van het signaal in de vaste stof NMR. Hij streeft naar een specifiek analytisch instrument voor oppervlakte-studies en onderzoek over membranen en…
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Imaging of alkyne-functionalized ruthenium complexes for photoactivated chemotherapy
In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.
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The role of autophagy during carbon starvation in Aspergillus niger
Autopaghy is an intracellular degradation system which targets cytosolic components to lytic compartments for degradation and recycling of the building blocks of the cell.
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CO2 reduction on post-transition metals and their alloys: an industrial approach
This thesis focuses on the synthesis, characterization and performance towards CO2 electroreduction of mono and bi-metallic particles based on p-block metals
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Investigations on the role of impaired lysosomes of macrophages in disease
The research described in this thesis combines the latest insights in lysosomal function with lysosome centred cell signalling.
- Onderzoeksfaciliteiten
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The hunt for frozen organic molecules in space
Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.
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Less is more: reduced mycelial heterogeneity for improved production of enzymes and antibiotics
Hoe kan de techniek van cell wall engineering worden ingezet zodat de industrie streptomyceten beter kunnen verwerken tot nieuwe antibiotica?
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Nucleosome stacking in chromatin fibers probed with single-molecule force- and torque-spectroscopy
In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.
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More is alive: emergent multi-scale order & collective flows in tissues
The overarching goal of this thesis is to set the foundations, but also make the first essential steps towards establishing a comprehensive, mesoscopic, hydrodynamic theory of epithelial tissues. The stage is set by an exhaustive study of topological defects in passive p-atic liquid crystals, singularities…
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High throughput microscopy of mechanism-based reporters in druginduced liver injury
Promotor: B. van de Water
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Media en interactie
Media & interactie is waar kunstmatige intelligentie en machine learning samenkomen met filosofie, cognitieve wetenschap en de creatieve kunsten. Voorbeelden van onderzoeksvragen in dit domein zijn: ‘Kan een algoritme naar menselijke maatstaven creatief zijn?', 'Kunnen creatieve processen, zoals het…
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The physics of nanowire superconducting single-photon detectors
Promotores: Prof.dr. D. Bouwmeester, Prof.dr. A. Fiore (TU Eindhoven)
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Applications of multisource data-based dynamic modeling to cell-cell signaling and infectious disease spreading
Promotie
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Anjali PanditWiskunde en Natuurwetenschappen
a.pandit@chem.leidenuniv.nl | +31 71 527 4198
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Huub de GrootWiskunde en Natuurwetenschappen
groot_h@chem.leidenuniv.nl | +31 71 527 4539
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Zionism: An Emotional State
Lezing, Publieke lezing
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The State Legal Pluralism
Promotie
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Ice and Gas in Protostellar Clouds and Planet-forming Disks
This thesis takes steps toward understanding the interaction between gas-phase and solid-state molecules in star- and planet-forming regions.
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Click to Release for Immunce Cell Activation
Promotie
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Nico Schrijver benoemd als arbiter Terugtrekkingsakkoord EU-VK
Nico Schrijver emeritus hoogleraar Internationaal Publiekrecht en staatsraad bij de Raad van State is door de Europese Unie en het Verenigd Koninkrijk benoemd als lid van het arbitragepanel dat bevoegd is om geschillen te beslechten over het terugtrekkingsakkoord EU-VK.
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Het Groothertogdom Litouwen en de Gouden Horde
Did the Jochids leave their mark on the Grand Duchy, taking into account that the Lithuanian state was one of the main successor states of the Great Horde in the 16thCentury?
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Meeloopdag Molecular Science & Technology
Studievoorlichting
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Genetic-Tracing of CD8+ T cell fate decisions
Promotie
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Evolutionary diversification and historical biogeography of Orchidaceae in Central America with emphasis on Costa Rica and Panama
In this thesis, I targeted the orchid genus Lepanthes, one of the six genera of angiosperms that surpasses 1,000 species in the Neotropics, as a study model to investigate the evolutionary processes that promoted species diversifications.
- Afstudeerceremonie MSc Media Technology
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Development of an Adverse Outcome Pathway (AOP) for metallic nanoparticles
What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?
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Bioorthogonal Labeling Tools to Study Pathogenic Intracellular Bacteria
In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.
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Dynamics of TNFalpha signaling and drug-related toxicity
In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.
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Ecological functioning of bacterial chitinases in soil
Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)
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Discovery and exploitation of the transcriptional regulatory system of pectinases in Aspergillus niger
Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.
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Circulating cells as biomarkers in cardiovascular disease : the difference between men and women
Promotor: J. Kuiper
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The role of the interleukin 12 family in atherosclerosis
Promotor: Johan Kuiper, Co-promotor: Saskia C.A. de Jager
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Coiled-coils on lipid membranes: a new perspective on membrane fusion
Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros