Stochastic resetting is simple enough to be approached analytically, yet modifies stochastic processes in a non-trivial way.

Promotor: F.S. de Boer Co-promotor: P. T. de Gouw

In 2015 the Pascalchair of the Faculty of Science, Universiteit Leiden and in particular of Leiden Institute of Advanced Computer Science, is held by Prof. Dr. Natasa Jonoska, University of South Florida, Tampa, USA.

Structural variants (SVs) are the hidden architecture of the human genome, and are critical for us to understand diseases, evolution, and so on.

By training with virtual opponents known as computer generated forces (CGFs), trainee fighter pilots can build the experience necessary for air combat operations, at a fraction of the cost of training with real aircraft.

In my thesis I study Majorana fermions from three different perspectives. The first one corresponds to non-interacting Majorana fermions that, however, pose non-trivial topological properties. The second one corresponds to strongly interacting Majoranas and the third to relic neutrinos. No one knows…

Lezing, Tuesday Talks: Science Insights

What are the behaviours of plant traits throughout various points in the growing season in a radiative transfer model framework and how well can this knowledge be integrated through data assimilation to provide priors for robust local and global vegetation products and analysis?

Marokko is een van de weinige landen in Noord-Afrika die aan de Arabische lente een vreedzame vorm heeft weten te geven door het pad van brede, gestage politieke hervormingen op te gaan. De Marokkaanse overheid verklaart de relatieve maatschappelijke rust daarnaast ook door haar islampolitiek, gericht…

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Disclaimer: Manuscripten die te maken hebben met het Resilience Center zijn alleen voor academische doeleinden en zijn niet bedoeld voor massaverspreiding of kopiëren. Raadpleeg de toepasselijke wetten voor eerlijk gebruik, inclusief de beperkingen van de houders van auteursrechten op publicaties.

Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.

Promotor: Prof.dr. A. Doelman, Co-promotor: V. Rottschäfer

Promotores: S.J. Edixhoven, F. Andreatta

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Promotor: M. Danhof, Co-promotor: E.C.M. de Lange

Kersverse hoogleraar Gerard van Westen werkt op het snijvlak van kunstmatige intelligentie en medicijnontwikkeling. Voor de nieuwe leerstoel Artificial Intelligence and Medicinal Chemistry zet hij computermodellen in om medicijnontwikkeling efficiënter te maken. ‘ Ons ultieme doel is een virtuele mens…

Promotor: G. J. Kroes

Dissociative chemisorption is an important reaction step in many catalytic reactions.

CMLCA is a software tool that supports the technical steps of the Life Cycle Assessment. The focus of the program is on advanced computational aspects of life cycle inventory calculations.

In this thesis, we have studied cell images from two types of cells, including pollen grains and the immune cells, neutrophils. These images are captured using a bright field microscope and a confocal microscope.

Dankzij data science kunnen we grote hoeveelheden van gerelateerde informatie in kaart brengen en doorzoeken. Dit levert allerlei nieuwe inzichten op, bijvoorbeeld in wereldwijde complexe financiële structuren of sociaal-maatschappelijke problemen als eenzaamheid.

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

Promotores: Wim Jiskoot; Ferry Ossendorp

Promotores: J. Jonkers, K.E. de Visser

Promotor: Richard D. Gill

The lipid membrane is a basic structural component of all living cells. Embedded in this nanometer-thin barrier, membrane proteins shape the membrane and at the same time respond to the shape of the membrane.

Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe

Promotor: P.D. Grünwald

As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.

De onderzoeksgroep Digital Archaeology beheert twee computerlaboratoria voor verschillende doeleinden: een onderwijslab en een onderzoekslab.

In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.

Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia

The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…

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Promotor: S.M. Verduyn Lunel