1,504 zoekresultaten voor “effective date development” in de Publieke website
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Onderzoek
De afdeling Jeugdrecht en Gezondheidsrecht doet onderzoek naar de positie van het kind in het nationale en internationale recht.
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Verkenning van islamisering
Kunnen we spreken van één enkel islamitisch discours op gebieden zoals politiek, strijd, economie en duurzame ontwikkeling? En welke interactie bestaat er tussen dit islamitisch denken en 'westers' denken?
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Linkages of Sustainability
Exploring linkages between energy and material use and implications for sustainable development.
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The interplay between lipids and the immune system in atherosclerosis
Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.
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Multi-omics studies of the control of growth and antibiotic production of Streptomyces
Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).
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Towards a Sustainable and Circular Metals Economy
In-use stocks of products can be considered as intermediaries between human needs and the physical world.
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Constraints on large-scale implementation of BioSolarCells, Early stage assessment of environmental value propositions
What performance criteria does a new technology have to fulfill in order to be added to the list of future energy options and what constraints exist in terms of broad market penetration?
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Hersenverbindingen voorspellen impulsiviteit bij pubers
Hersenverbindingen hangen bij pubers samen met impulsiviteit. Bovendien voorspellen ze welke pubers over twee jaar impulsievere keuzes maken, ontdekten Leidse psychologen.
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Extended Essays
Leiden University’s Academic Challenge
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Voorlichtingsactiviteiten
Wil je meer weten over de masterspecialisatie Nederlandse Politiek? Wil je kennis maken met studiestad Den Haag? We organiseren verschillende voorlichtingsactiviteiten om jou te helpen bij je keuze.
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MA International Relations Online Q&A
Studievoorlichting
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eHealth for all? Towards usable and effective eHealth services in different health care settings
Promotie
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Helft jonger, evenveel inzicht
Je zou denken dat 12-jarigen meer weten over drijven en zinken dan 6-jarigen. Uit onderzoek blijkt echter dat de individuele verschillen in inzicht erg groot zijn. Sommige 6-jarigen hebben een beter natuurkundig inzicht dan 12-jarigen.
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Xiaoyang Zhong
Wiskunde en Natuurwetenschappen
x.zhong@cml.leidenuniv.nl | +31 71 527 5148
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Joost Visser
Wiskunde en Natuurwetenschappen
j.m.w.visser@liacs.leidenuniv.nl | +31 71 527 2727
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Chenguang Gao
Wiskunde en Natuurwetenschappen
c.gao@cml.leidenuniv.nl | +31 71 527 4917
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PhD Candidate in Social Norms and Gender Inequalities in the Labour Market (0.8-1.0 fte)
Rechtsgeleerdheid
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PhD Candidate in Economics (0.8-1.0 fte)
Rechtsgeleerdheid
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Postdoctoral Researcher in the project "Do we owe anything to ourselves?"
Sociale Wetenschappen, Psychologie
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Using insertional mutagenesis to identify breast cancer drivers and therapy resistance genes in mice
In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.
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First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and children
Growth and development affect the metabolism of drugs administered to neonates, infants, and children.
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Human skin equivalents for atopic dermatitis: investigating the role of filaggrin in the skin barrier
Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri
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Systems pharmacokinetic models to the prediction of local CNS drug concentrations in human
Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.
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Nanoparticle-based combination drug delivery systems for effective cancer treatment
Promotie
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Vernieuwend Leids onderzoek ontvangt NWO-subsidie
Hoogleraar Annemarie Meijer en dr. Sander Wezenberg ontvingen op 24 januari een NWO-subsidie voor hun onderzoek. De subsidie is toegekend binnen het Open Competitie ENW-M-programma en is bedoeld voor vernieuwende onderzoeksgebieden die de basis kunnen zijn voor onderzoeksthema’s van de toekomst.
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Kernteam
Het kernteam van het PDC is verantwoordelijk voor onderzoek en ontwikkeling van de LMW-methode en voert het beheer van de LMW trajecten binnen de verschillende deelnemende instellingen.
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Management of Small-Scale Fisheries at the Elephant Marsh in Malawi
Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…
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Chemical tools to study the cannabinoid receptor type 2
The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…
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Targeting of antigen-presenting cells with mannosylated conjugates
This thesis describes the development of a variety of mannosylated conjugates. Antigen presenting cells bear mannoside recognizing receptors that actively transport antigen into the cell. This thesis exploits this feature for the development of improved vaccines.
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Europa en de sociaal-economische kracht van astronomie
Het European Regional Office of Astronomy for Development (E-ROAD) heeft zijn eerste conferentiesessie gehouden tijdens de virtuele EAS Annual Meeting 2020, de grootste astronomieconferentie in Europa. E-ROAD is een initiatief van de Internationale Astronomische Unie en de Universiteit Leiden. Het zet…
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SCS Courses
The coursework within the Science Communication and Society (SCS) specialisation prepares students for internships and a career in communication about science and health.
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Photo-activation of ruthenium-decorated upconverting nanoparticles
Metal-based prodrugs based on ruthenium(II) polypyridyl complexes have proven to be very suitable for application in both photodynamic therapy (PDT) and photo-activated chemotherapy (PACT).
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Using mouse models to uncover genes driving tumorigenesis and therapy resistance in human breast cancer
To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.
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Targeting Human Proteasomes: Substrates, Inhibitors and Prodrugs
Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.
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Iber Kasehatan in Sukamiskin: Utilisation of the Plural Health Information and Communication System in the Sunda Region of West Java, Indonesia
This study has been carried out in the community of Sukamiskin, a kelurahan (‘village’) in Bandung, the Capital of West Java Province, located in the Sunda Region of Indonesia.
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Preclinical therapy development in FSHD
Promotie
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Nieuwe inzichten in mycobacteriële infecties met NWO-beurs
Waarom zijn mycobacteriën zulke succesvolle ziekteverwekkers? En zijn er verdedigingsmechanismen in het lichaam die helpen een infectie iets te verminderen? Om dit te achterhalen, heeft Annemarie Meijer de NWO Open competitie ENW-XL-beurs toegekend gekregen. Ze gaat niet alleen aan de slag. Aan het…
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From molecules to monitoring: Integrating genetic tools into freshwater quality assessments
Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.
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Waste Collection Systems Assessed and Good Practices Identified (COLLECTORS)
What is the environmental impact of different waste collection systems across Europe? How can the collection be improved when considering collection, sorting, and treatment, as well as use options for secondary materials?
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Spatiotemporal building stock modeling for residential decarbonization in the Netherlands
Decarbonizing the building stock is critical for realizing the climate-neutral target for the Netherlands.
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Systematics, Epidermal defense and Bioprospecting of Wild Orchids
This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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A macro level assessment of material circularity
A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.
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Instituut voor Metajuridica
De rechtswetenschap is een verzamelnaam voor de 'juridica' en 'metajuridica'.
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Substances from Cradle to Grave
Materials balances have been used in the recent past for the analysis of substance oriented environmental problems and the formulation of measures for environmental policy. In this study an integrated tool, based on the materials balance principle, has been developed for the analysis of both environmental…
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Understanding the complexity of intelligence problems
The complexity of an intelligence problem determines to a great extent the certainty that can be provided by intelligence and security services.
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Towards controlled microneedle-mediated intradermal immunization
Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.
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Unsprayed field margins: effects on environment, biodiversity and agricultural practice
A management strategy has been developed for field margins to reduce pesticide drift to non-target areas and to promote biodiversity on arable land. To this end, 3 and 6 m wide strips along the edges of winter wheat, sugar beet and potato crops have been left unsprayed with herbicides and insecticides…
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Learning from small samples
Learning from small data sets in machine learning is a crucial challenge, especially when dealing with data imbalances and anomaly detection. This thesis delves into the challenges and methodologies of learning from small datasets in machine learning, with a particular focus on addressing data imbalances…
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Onderzoek
De Faculteit der Rechtsgeleerdheid verricht hoogwaardig onderzoek naar acht onderzoeksprogramma's.