668 zoekresultaten voor “other” in de Publieke website
-
Mass Spectrometry-Based Degradomics Analysis of Toxoid Vaccines
The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.
-
Crossed product algebras associated with topological dynamical systems
Promotor: S.M. Verduyn Lunel, Co-promotoren: M.F.E. de Jeu, S.D. Silvestrov
-
Inhibitors and probes targeting mannanases
This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…
-
Novel pharmacometric techniques to quantify the pharmacodynamics of analgesics
The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.
-
X-ray spectroscopy of interstellar dust: from the laboratory to the Galaxy
In this thesis, we present new laboratory data of interstellar dust analogues.
-
The Ornithology of the Baudin expedition (1800-1804)
The expedition commanded by Nicolas Baudin to Tenerife, Mauritius, Australia, Timor and South Africa in 1800-1804 is fully researched in regard to ornithology.
-
Developing systems for high-throughput screening of infectious diseases using zebrafish
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer
-
Can traditional forest management protect and conserve ironwood (ulin) stands? An option and approach in East Kalimantan
Promotores: G.A. Persoon, H.H. de Iongh
-
Species Literacy: The perception and cultural portrayal of animals
In his dissertation Michiel Hooykaas outlines the results of six empirical research projects focused at biodiversity awareness in the Netherlands, specifically people’s knowledge about animals.
-
The assembly history of the milky way nuclear star cluster
Promotor: P. T. de Zeeuw, Co-promotor: N. Neumayer; G. van de Ven
-
Targeted Informed consent: empowering young participants in medical-scientific research
Promotor: J.M. van den Broek Co-promotor: M.C. de Vries
-
Faith in Democracy. Justice, Politics and Transcendence
This book explores the spiritual potential of faith, mysticism and transcendence in answer to the dangers of a mythologised state and the sacro-sanctification of (liberal) democracy and its rule of law.
-
The Proliferation of Dissenting Opinions in International Law
Op 8 juli 2020 verdedigde Andres Sarmiento Lamus zijn proefschrift 'The Proliferation of Dissenting Opinions in International Law'. Het promotieonderzoek is begeleid door promotoren prof.dr. L.J. van den Herik en prof.dr. Y.A.A.S. Radi (UCLouvain).
-
Activity-based protein profiling in drug discovery
In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.
-
In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska
-
Photothermal circular dichroism studies of single nanoparticles
In this work, we investigate the minute circular dichroism effects of single nanoparticles.To this aim, we apply photothermal imaging with a polarization-modulated heating beam.
-
Algorithms for finite rings
Promotores: H.W. Lenstra, K. Belabas (University of Bordeaux)
-
Data Centres for Natural Recources and Products
Creating information portals for support of European environmental policy.
-
Profinite groups with a rational probabilistic zeta function
Promotores: H.W. Lenstra, A. Lucchini
-
Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgery
Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst
-
Inverse Jacobian and related topics for certain superelliptic curves
To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.
-
Ecology of the Ethiopian wolf (Canis simensis Rüppell 1835) in a changing landscape: Human carnivore interactions in Afroalpine ecosystems of
Ethiopian wolves are endangered diurnal Afroalpine rodent hunters. I investigated the interaction between wolves, rodents and human land use in Borena Sayint National Park (BSNP), Abune Yosef and Aboi Gara in Ethiopia.
-
Discovery of novel Antibiotics from Actinomycetes by Integrated Metabolomics & Genomics Approaches
Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi
-
Improved Strategies for Distance Based Clustering of Objects on Subsets of Attributes in High-Dimensional Data
This monograph focuses on clustering of objects in high-dimensional data, given the restriction that the objects do not cluster on all the attributes, not even on a single subset of attributes, but often on different subsets of attributes in the data.
-
De verzamelwoede van Martinus van Marum (1750-1837) en de ouderdom van de aarde
Promotor: F.J. van Lunteren, E. Jorin
-
Multi-objective mixed-integer evolutionary algorithms for building spatial design
Multi-objective evolutionary computation aims to find high quality (Pareto optimal) solutions that represent the trade-off between multiple objectives.
-
Dynamics of the Oort Cloud and Formation of Interstellar Comets Santiago Torres Rodriguez
The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.
-
Evolutionary adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
-
Metabolomic characterization of plant exudates and their correlation with plant defense systems
Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.
-
Area Studies: Azië & het Midden-Oosten
Het Leiden University Institute for Area Studies (LIAS) wijdt zich aan de bestudering van Azië en het Midden Oosten, vanaf de Oudheid tot het heden.
-
Combining monitoring with run-time assertion checking
Promotor: F.S. de Boer, Co-promotor: M.M. Bonsangue
-
Bakti and Sayan traditions among the Tenggerese people in East Java: the role of indigenous institutions in integrated elderly care development
This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…
-
A chemical biology approach for targeting of ligand-drug conjugates
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot
-
Vaccination and Targeted Therapy Using Liposomes; Opportunities for Treatment of Atherosclerosis and Cancer
This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.
-
Abiotic depletion in LCIA
Possible improvements for the assessment of abiotic depletion in LCA.
-
Stock-driven Scenarios on Global Material Demand
The role of material production as a driver of environmental impacts is increasing, which calls for a better understanding of global material flows. This thesis explores the role of in-use stocks of products, buildings and infrastructure as a key driver of global material demand and discusses the implications…
-
Novel factors modulating AGC kinase signaling-controlled polar auxin transport
The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.
-
High-throughput simulation studies of angiogenesis - Reverse engineering the role of tip cells and pericytes in vascular development
Promotor: Prof.dr. R.M.H. Merks
-
Exploring future multi-messenger Galactic astronomy
For centuries astronomers studied the Universe by collecting light. Nowadays, we are living in times of great technological advancements, which allow us to explore our Universe in a new way - though gravitational wave radiation.
-
Prosecutorial Discretion in International Criminal Justice
Op 23 februari 2022 verdedigde Cale Davis het proefschrift 'Prosecutorial Discretion in International Criminal Justice'. Het promotieonderzoek is begeleid door prof.dr. C. Stahn en dr. J.C. Powderly.
-
Studentenleven
Leiden is een echte studentenstad. Meld je aan voor een studievereniging of studentenvereniging om van jouw studietijd een onvergetelijke tijd te maken!
-
Studentenleven
Leiden is een echte studentenstad. Meld je aan voor een studievereniging of studentenvereniging om van jouw studietijd een onvergetelijke tijd te maken!
-
Studentenleven
Leiden is een echte studentenstad. Meld je aan voor een studievereniging of studentenvereniging om van jouw studietijd een onvergetelijke tijd te maken!
-
Studentenleven
Leiden is een echte studentenstad. Meld je aan voor een studievereniging of studentenvereniging om van jouw studietijd een onvergetelijke tijd te maken!
-
Studentenleven
Leiden is een echte studentenstad. Meld je aan voor een studievereniging of studentenvereniging om van jouw studietijd een onvergetelijke tijd te maken!
-
Evolution and development of orchid flowers and fruits
To gain more insight into the evolutionary development of orchid flowers and fruits, the orchid species Erycina pusilla was studied. The evolutionary origin of the median petaloid sepal, the callus on the labellum, and the stelidia was studied.
-
Nucleosome stacking in chromatin fibers probed with single-molecule force- and torque-spectroscopy
In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.
- Onderzoeksprojecten
-
Jean Monnet Chair of Moritz Jesse
Moritz Jesse has been awarded a Jean Monnet Chair by the European Commission. In his MIND-EU Project he will focus on a coherent way to teach Migration, Integration, and Non-Discrimination at Leiden Law School at bachelor and master level.
-
GLOBOX
GLOBOX is a spatially differentiated multimedia fate, exposure and effect model. It is used for the calculation of spatially differentiated LCA characterisation factors on a global scale.