Rechtsgeleerdheid

What is movements and corridors of the Bornean pygmy elephant in Sebuku forest? What is the nature of human-elephant conflict in Nunukan District in time and space? What are the diets of the Bornean elephants related to crop raiding?

Zet een plant in de vensterbank en hij zal binnen enkele uren naar het licht gegroeid zijn. Voor het eerst is dit mechanisme in planten op moleculair niveau in kaart gebracht door Leidse biologen en onderzoekers uit Gent en Lausanne. Ze publiceerden hierover in het prestigieuze Nature Cell Biology.

Hoe kan de techniek van cell wall engineering worden ingezet zodat de industrie streptomyceten beter kunnen verwerken tot nieuwe antibiotica?

This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.

Promotor: V. Vitelli, Co-promotor: J. Paulose

Promotores: Prof.dr. B.R. Katzy, Prof.dr. K. Sailer (Munich University)

Polycyclic aromatic hydrocarbons (PAHs) are the most abundant class of organic compounds in space. The PAH field evolves from the constant interaction between experimentalists, theorists, modellers and observers. While laboratory research and quantum chemical calculations together set up the molecular…

Promotor: Koen Kuijken Co-promotor: Henk Hoekstra

Planets are formed in disks of gas and dust around young stars.

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

Cardiovascular syndromes are the major cause of death in Western societies.

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

Promotor: G.P. van Wezel, Co-promotor: D. Claessen

Voltammetry plays a crucial role in modern scientific research by offering valuable insights into the electrochemical properties of materials, with wide-ranging applications in fields such as materials science, energy storage, corrosion studies, and sensor development.

Promotor: G.A. van der Marel, Co-promotor: D.C. Codée

Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh

Sustainable energy from wind and solar is most readily available near the sea.

All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).

Every organisms in the tree of life faces the same challenge: the length of its DNA exceeds the volume of the cell it needs to fit in. Several strategies have evolved to solve this problem, one of them being the expression of proteins that bind and organize the DNA.

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.

Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.

Galaxies are environments where gas coalesces, cools, and is converted into stars. However, it remains unclear the exact mechanisms through which galaxies acquire, redistribute and lose their gas.

The aim of this thesis is to develop and study a robust and adaptable scaffold for supramolecular polymer self-assembly in water.

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.

Promotores: Prof.dr. A.G.G.M. Tielens, Prof.dr. L. Kaper (UvA)

Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.

Lezing, Kaiser Lente Lezing

What are the global relationships between environmental conditions and abundance of distinct types of mycorrhizal fungi in soil and plant roots?

Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.

In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.

Promotor: Prof.dr. M. Ubbink

This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.

Metal-based prodrugs based on ruthenium(II) polypyridyl complexes have proven to be very suitable for application in both photodynamic therapy (PDT) and photo-activated chemotherapy (PACT).

Promotor: Prof.dr. A.G.G.M. Tielens

Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.

In this thesis, the research focuses on the properties of dark matter and dark matter haloes and how they connect with the galaxies we can observe in the Universe.

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.