1,273 zoekresultaten voor “been into” in de Publieke website
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Understanding the Surface Structure of Catalysts and 2D Materials at the Atomic Scale
The work in this thesis demonstrates how to obtain an atomic-scale picture of a diverse set of complex surface structures observed using STM, under disparate conditions.
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Observing what cannot be observed: computational electrochemistry from carbon to hydrogen
In this thesis, we consider various (electro)chemical phenomena at surfaces and nanoparticles and their underlying atomistic processes, which we studied using first-principles methods such as density functional theory.
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Afdeling Industriële Ecologie (CML-IE)
The department of Industrial Ecology is dealing with research into the development of tools for decision making on sustainable production and consumption.
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Catalysis of the electrochemical water oxidation to oxygen
Promotor: Prof.dr. M.T.M. Koper, Co-Promotor: F. Calle-Vallejo
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Adjuvanted nanoparticulate seasonal influenza vaccines
Promotor: W. Jiskoot, Co-promotor: A. Kros
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Mechanistic modelling of drug target binding kinetics as determinant of the time course of drug action in vivo
Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.
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Harnessing zebrafish xenograft models for ocular melanoma treatment discovery
The aim of this thesis was to develop novel treatment strategies for different types of eye melanoma utilizing zebrafish models. We first establish orthotopic and ectopic xenograft models for uveal and conjunctival melanoma by engraftment of the immortalized cells derived from these tumors into zebrafish…
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The Agta of the Northern Sierra Madre. Livelihood strategies and resilience among Philippine hunter-gatherers
Promotores: G. Persoon, R. Schefold
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Star-Forming Galaxies at the Cosmic Dawn
Promotor: Prof.dr. M. Franx, Co-Promotor: Rychard Bouwens
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Interaction with sound for participatory systems and data sonification
This thesis deals with the use of sound in interactions in the context of participatory systems and data sonification. We investigate an interactive environment where participants perceive information of the data through sound elements.
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Material constraints of selected energy pathways
Examining if large scale application of new energy pathways can be constrained by materials and emissions.
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The LeiCNS-PK3.0 model development and applications: healthy-to-diseased CNS pharmacokinetic translation
Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…
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Sustainable Chemistry and Biotechnology
If mankind wants to survive into the 22nd century, we will need to change the way we live drastically. The human impact on our planet is everywhere, we are changing the atmosphere, the oceans and the land, leading to global warming, climate change, loss of biodiversity and pervasive pollution. There…
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Electroextraction approaches for preconcentration of metabolites
In this thesis, we developed new ways to use a technique called electroextraction (EE) to extract charged molecules from one liquid into another using an electric field.
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20th century changes in the Dutch flora
Description of 20th century changes in the Dutch flora: Description and interpretation (1999 - 2005)
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Development of life cycle assessment for residue-based bioenergy
Wat zijn de belangrijkste thema's in het uitvoeren van systemen voor bio-energie ?
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Inkomen verdeeld, trends 1977-2019
Op 14 oktober 2021 is het publieksboek uitgekomen. Sindsdien kunnen alle bestanden en links via deze website geraadpleegd worden.
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Economic value of non-timber forest products among Paser Indigenous People of East Kalimantan
Promotor: G.A. Persoon, Co-promotor: H.H. de Iongh
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Evaluating Asian aquaculture using Life Cycle Assessment (LCA)
Are there significant differences among the environmental impacts resulting form the production of Asian aquaculture commodities and what are the main causes for these?
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To explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors
Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…
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The Metals Programme
Accumulation of metals in economy and environment and its associated risks, within the Netherlands and the EU.
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Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination
CONCLUSION: This study demonstrates that human macrophages can be induced to exert direct anti-tumor activity against osteosarcoma cells. Our observation that the induction of macrophage anti-tumor activity by L-MTP-PE required IFN-gamma may be of relevance for the optimization of L-MTP-PE therapy in…
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Targeting for success: Mechanistic insights into microRNA-based gene therapy for Huntington disease
Promotie
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Plant-soil interactions determine ecosystem aboveground and belowground processes in primary dune ecosystems
Soil biodiversity is of great importance for the maintenance of multifunctionality in terrestrial ecosystems.
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Replacing the needle and syringe for vaccine administration
Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra
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Chemical synthesis of fragments of galactosaminogalactan and pel polysaccharides
The work described in this Thesis is focused on the assembly of oligosaccharide fragments derived from a fungal polysaccharide, galactosaminogalactan (GAG) and fragments of the exopolysaccharide Pel, generated by Pseudomonas aeruginosa.
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Cyclophellitol and its derivatives: synthesis and application as beta-glycosidase inhibitors
Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel
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ALGANT
Fundamental research in the ALgebra, Geometry And Number Theory
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NMR studies of protein-small molecule and protein-peptide interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal
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Translational Symmetry Breaking in Holographic Strange Metals
In this thesis, we have used numerical approaches to study the effects of translational symmetry breaking on strange metallic systems as realised by the holographic duality.
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Política, Cuerpo e Identidad
This book aims to be a point of reflection and debate for journalists, academics and students to recognize a fundamental task in the duty of the communications professional, which is to influence through their daily work and their routines in order to achieve a more inclusive and plural society, through…
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Towards an ab-axis giant proximity effect using ionic liquid gating
In this Thesis, novel charge induction mechanisms of ionic liquids are treated, tested and experimented on complex oxides, in particular cuprates.
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The Heritage Arena
In Europe a number of production and communication strategies have long tried to establish local products as resources for local development. At the foot of the Alps, this scenario appears in all its contradictions, especially in relation to cheese production. The Heritage Arena focuses on the saga…
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Unveiling the nature of giant radio galaxies
The thesis deals with the study of giant radio galaxies (GRGs), which are radio galaxies of megaparsec sizes.
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The role and analysis of molecular systems in electrocatalysis
Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.
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Investigations of Radiation Pressure: Optical side-band cooling of a trampoline resonator and the effect of superconductivity on the Casimir
This thesis consists of two subjects, that are both a consequence of radiation pressure.
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Functionalizing monolayer graphene as a proton-selective membrane for direct methanol fuel cells
This thesis focused on the exploration of monolayer graphene as a membrane in direct methanol fuel cell (DMFC) applications, with improvements achieved through plasma exposure or damage- free chemical functionalization.
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Reliable and Fair Machine Learning for Risk Assessment
The focus of this thesis is on the technical methods which help promote the movement towards Trustworthy AI, specifically within the Inspectorate of the Netherlands.
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Star formation and aging at cosmic noon: the spectral evolution of galaxies from z=2
Promotores: Prof.dr. M. Franx, Prof.dr. P.G. van Dokkum (Yale University)
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Discovery of FLT3 inhibitors for the treatment of acute myeloid leukemia
The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.
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Samenstelling team
Zelfredzaamheid en sociale bescherming over de levenscyclus
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Assessing global regionalized impacts of eutrophication on freshwater fish biodiversity
Freshwater biodiversity has been threatened by eutrophication due to excessive nutrients in the environment. Releasing the freshwater species from such pressures requires efforts from industry and manufacturers to avoid emissions to vulnerable and high-risk regions.
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Ecology of the Ethiopian wolf in a changing landscape: Human carnivore interactions in Afroalpine ecosystems of Ethiopia
Do Ethiopian wolves change their diet and foraging strategy in the landscape under different land uses? How land use affect Afro-alpine rodent Communities? How important are Afro-alpine natural resources utilisation for local livelihoods? What is the human perception of conflict in the Afro-alpine a…
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Does knowledge of environmental performance change farmer's behaviour?
Does knowledge of environmental performance change farmer's behaviour?
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Systematic investigations into the role of ceramide subclass composition on lipid organization and skin barrier
Promotie
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Extremely Loud & Incredibly Far: Observing Radio Bright AGN into the Cosmic Dawn
Promotie
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Contemplations into Respiration: Effects of breathing and meditative movement on body and mind
Promotie
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Novel Imaging Insights into Cardiac Remodeling, Myocardial Function and Risk Stratification in Cardiovascular Disease
Promotie
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Studies into Interactive Didactic Approaches for Learning Software Design Using UML
Promotie
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Insights into the mechanism of electrocatalytic CO2 reduction and concomitant catalyst degradation pathways
Promotie