Promotores: H.A. Udo de Haes, H.H.T. Prins, Co-promotor: H.H. de Iongh

Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.

Op 13 januari 2022 verdedigde Pie Habimana het proefschrift 'Harmful Tax Competition in the East African Community'. Het promotieonderzoek is begeleid door prof.dr. H. Vording en prof.dr. S.C.W. Douma (UvA).

In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.

The key purpose of this project is to study tautological relations on the level of closed differential forms or even integral cochains (i.e. we don't take classes in cohomology).

Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert

In recent decades, climate change has led to more frequent and severe drought events, causing serious consequences such as increased forest mortality and significant crop yield losses. Understanding how drought affects plants, especially economically important herbaceous species, is crucial for predicting…

This thesis studied in depth the energy use and CO2 emissions of the industrial sector in China.

The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles.

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

Promotor: M.K. Richardson, Co-Promotor: F. Witte

Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm

Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst

Promotor: Prof.dr. R.M.H. Merks

The name ‘Jambi flora’ refers to fossil plants found as part of a rock formation from the Early Permian (296 million years old), located in the Jambi Province of Sumatra, Indonesia.

Mining time series is a machine learning subfield that focuses on a particular data structure, where variables are measured over (short or long) periods of time.

The sequence-dependence of biomolecular interactions involving nucleic acids and proteins is essential for numerous processes inside the cell. Insights into the underlying molecular mechanisms have been obtained using various biochemical and biophysical methods on two different levels — bulk and sin…

The research presented in this thesis makes use of small molecules (as H2 , D2 and O2 ) on well-defined single crystal surfaces (flat Pt(111), flat Cu(211) and curved Pt(111)) to elucidate the role of surface structure and degrees of freedom in the reactant in specific surface reactions.

Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.

We strive to address the challenge of constructing a modeling language to write software which can take advantage of recent hardware developments (multicore, cloud) without compromising in its abstraction levels.

This thesis is dedicated to the exploration of the primordial dark ages: unknown physics during the earliest stages of the Universe’s expansion that have not yet been directly probed by observations. Cosmic inflation is a burst of exponential expansion of space after the “Big Bang”.

The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

Promotor: Prof.dr. J. den Hertog

This thesis describes the functional analysis of the Arabidopsis AHL15 gene.

Mechanical metamaterials are man-made materials which derive their unusual properties from their structure rather than their composition.

Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort

Op 1 april 2020 verdedigde Marc Broekema zijn proefschrift 'Cognitive Bias in the Judgment of Business Valuations and Valuators'. Het promotieonderzoek is begeleid door promotor prof. dr. J.I. van der Rest.

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae

Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer

The European Council and the European Commission have a similar role in agenda setting. Both place issues on the EU agenda. However, these institutions have distinct designs. They have different political attributes (the European Council has considerably more political authority) and information-processing…

Aan de opleidingen van het Centre for Professional Learning op het gebied van Terrorisme, Recht en Veiligheid zijn verschillende (research) fellows verbonden. De fellows geven advies over de inhoud van het curriculum en de verbinding tussen wetenschap en praktijk.

This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.

Promotores: Prof.dr. F. van Lunteren, Prof.dr. F.S. Gaastra

Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros

Control of infectious diseases poses continuous challenges for human health.

Op 21 oktober 2021 verdedigde Frederik Behre het proefschrift 'A European Ministry of Finance?'. Het promotieonderzoek is begeleid door promotor prof.dr. S.C.G. Van den Bogaert.

Leiden University and the Ministry of Infrastructure and Water Management are involved in a collaboration in the form of a research project titled 'Data-Driven Risk Assessment in Infrastructure Networks'

Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet

This thesis describes the development and validation of new high-contrast imaging techniques, with the ultimate goal of enabling the next generation of instruments for ELT-class telescopes to directly image Earth-like extra-solar planets orbiting around nearby stars.

This thesis takes steps toward understanding the interaction between gas-phase and solid-state molecules in star- and planet-forming regions.

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.

Promotors: Prof.dr. T.H.W. Bäck, Prof.dr. B. Sendhoff (Technische Universität Darmstadt)

Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

Promotores: Prof.dr. E.F. van Dishoeck, Prof.dr. C.P. Dullemond