Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

It is a common technique in global optimization with expensive black-box functions to learn a surrogate-model of the response function from past evaluations and use it to decide on the location of future evaluations.

Promotor: Prof.dr. S. Haring

Van zelfrijdende auto’s tot innovatieve medicijnontwikkeling, kunstmatige intelligentie (AI) gaat ons leven op uiteenlopende manieren fundamenteel veranderen. Onze computerwetenschappers bestuderen de technologie op een diep en fundamenteel niveau. Maar we zoeken ook naar medische toepassingen en antwoorden…

Promotores: H.W. Lenstra, K. Belabas (University of Bordeaux)

Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

Om de juiste klinische beslissingen te nemen of effectieve diagnostische testen en behandelingen te kunnen ontwikkelen, is het belangrijk om de onderliggende mechanismen van een aandoening of een bepaald gedrag te begrijpen.

Leiden University and the Ministry of Infrastructure and Water Management are involved in a collaboration in the form of a research project titled 'Data-Driven Risk Assessment in Infrastructure Networks'

The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…

Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…

Detecting planets during their formation stages is crucial for understanding the history and diversity of fully developed planetary systems like our own. However, observing young planets directly is challenging because they are often deeply embedded within their host protoplanetary discs, rich in gas…

Promotores: Prof.dr. F. van Lunteren, Prof.dr. F.S. Gaastra

Promotor: Prof.dr. M.A.G.J. Orrit

What are the flows of C&DW (e.g. bricks, concrete, gypsum and wood) in the case study countries ? How to define the specification for each material to be quantified? What indicators should be used to identify the pattern of each C&DW management system? How to interpret the MFA results in relation…

What is the population size/structure and distribution of tiger and leopard inside the Bardia National Park (BNP) compared with the population outside? What is the movement and home range and conflict pattern in time and space of tigers and leopards inside the BNP compared with outside? What constitutes…

Development of indicators to assess decoupling of economic development and environmental pressure in the EU-25 and AC-3 countries.

Promotor: G.A. Persoon, Co-promotor: H.H. de Iongh

Has the industrial sector in China effectively been decarbonizing in recent years, across different regions and subsectors, and is it plausible that it will reduce its CO2 emissions in conformity with national and internationally pledged emission goals?

Does the presence of Ring-necked parakeets negatively influence feeding and feeding behaviour of native bird species on artificial bird feeders and if so, what are possible solutions?

Producing green energy has become the main goal in our society in the search of reducing or eliminating the carbon emission from fossil fuels.

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf

In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.

What invertebrates live in the fields and edges? Do the populations change with landscape complexity?

Promotores: Prof.dr. G. Miley & Prof.dr. J.M. van den Broek

Hydrocarbonylation of alkenes with carboxylic acids in synthesis of carboxylic acid anhydrides is relatively less explored. We herein present a study and optimization of a palladium-catalyzed hydrocarbonylation reaction of alkenes using carboxylic acids as the nucleophile, by which acid anhydrides can…

Does a high quality prairie restoration in an urban/agricultural landscape provide invertebrates necessary for a sustainable ecosystem?

Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn

Identification of the products or product groups that have the greatest environmental impact from a life-cycle perspective using environmentally extended input-output analysis.

In this thesis, we use low-frequency and high-frequency radio observations to address the following questions regarding quasars: is the radio loud/quiet quasar dichotomy real?

Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.

In times of hardships or crisis, local people know how to deal with it using their resourcefulness. Although efforts are sometimes made by the government to help them, they are fully aware that community support is at least equally important.

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder

This thesis is about the study of hydrocarbons via infrared spectroscopy.

Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

Does roadside management in the mid-west USA increase invertebrate diversity similar to practices in Europe?

Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

The theoretical explanation of cosmic acceleration is nowadays one of the biggest puzzles in cosmology.

In meta-analysis, heterogeneity often exists between studies. In such cases, it is essential to investigate the sources of heterogeneity and understand the relationship between effect size and study characteristics (i.e., moderators).

Bacteria have the ability to alter their morphology in order to adapt to changing environments.

Dit op casestudies gebaseerde Engelstalige boek over multivariate analyse voor gevorderde studenten in de geesteswetenschappen legt de nadruk op beschrijvende, exploratieve analyses van verschillende soorten datasets uit een breed scala van subdisciplines, waarbij het gebruik van multivariate analyse…

Promotor: G.R. de Snoo, W. Kustiawan, Co-promotor: H.H. de Iongh

Promotores: P.G.L. Klinkhamer, P.M. Brakefield, Co-Promotor: M. Bruinsma

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

Promotor: M.A.G.J. Orrit

Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken

Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)