946 zoekresultaten voor “gene studies” in de Publieke website
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The Miliuseae revisited: phylogenetic, taxonomic, and palynological studies in a major clade of Annonaceae
Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou
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Ajay GandhiFaculteit Governance and Global Affairs
a.gandhi@luc.leidenuniv.nl | +31 70 800 9100
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Wim WillemsFaculteit der Geesteswetenschappen
w.h.willems@fgga.leidenuniv.nl | +31 6 5374 5961
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Nadia BourasFaculteit der Geesteswetenschappen
n.bouras@hum.leidenuniv.nl | +31 71 527 2088
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Mariana De Campos FrancozoFaculteit Archeologie
m.francozo@arch.leidenuniv.nl | +31 71 527 2437
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Marieke BloembergenFaculteit der Geesteswetenschappen
m.bloembergen@hum.leidenuniv.nl | +31 71 527 2459
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Ivo SmitsFaculteit der Geesteswetenschappen
i.b.smits@hum.leidenuniv.nl | +31 71 527 2545
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Sofia de JongFaculteit Rechtsgeleerdheid
s.w.m.de.jong@law.leidenuniv.nl | +31 71 527 2727
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synthesis and application of paramagnetic probes for protein structure studies
The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.
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Studies of dust and gas in the interstellar medium of the Milky Way
Promotor: Prof.dr. A.G.G.M. Tielens
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Characterization of candidate genes in unexplained polyposis and colorectal cancer
Promotie
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Viral gene therapy approaches for CRB1 retinal disease
Promotie
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Uncovering vulnerabilities in triple-negative breast cancer
Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.
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for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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Mirjam de BaarFaculteit der Geesteswetenschappen
m.p.a.de.baar@hum.leidenuniv.nl | +31 71 527 6416
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Shape Analysis for Phenotype Characterisation from High-throughput Imaging
We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska
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Exploring the chemical space of post-translationally modified peptides in Streptomyces with machine learning
The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.
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Spatial populations with seed-bank
In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…
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Low-temperature spectroscopic studies of single molecules in 3-D and on 2-D hosts
Spectroscopic studies on fluorescent single molecules in organic condensed matter does not only provide information about the molecule itself, but also its near environment. By suppression of phonon-induced broadening of spectral lines through cooling to low temperatures, small changes in the spectral…
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‘Suspect community or suspect category?‘, Journal of Ethnic and Migration Studies
Ragazzi, ‘Suspect community or suspect category?‘, Journal of Ethnic and Migration Studies
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Studies in Tocharian verbal morphology relevant to the cladistic position of Tocharian in Indo-European
Op 24 september promoveert Louise S. Friis. Het Leiden University Centre for Linguistics feliciteert Louise!
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De geboorte van een studie
De nieuwste opleiding van Universiteit Leiden heet Urban Studies. Hoe gaat dat, het opzetten van een compleet nieuwe studie? De bedenkers aan het woord.
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Development of a Kidney-on-a-Chip Model for Compound Screening and Transport Studies
Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…
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spFRET studies of nucleosome dynamics modulated by histone modifications, histone variants and neighboring nucleosomes
Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort
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Medieval Studies en Early Modern Studies: nieuwe keuzetrajecten in de Master
Aan de Universiteit Leiden zijn ruim honderd specialisten werkzaam op het terrein van de Middeleeuwen en de Vroegmoderne Tijd. Met ingang van 2017-2018 bundelen zij hun krachten binnen twee keuzetrajecten – Medieval Studies en Early Modern Studies – beide te volgen vanuit bestaande masteropleidingen…
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galaxies at low frequencies: high spatial and spectral resolution studies with LOFAR
Promotor: H.J.A. Röttgering, Co-promotor: G.K. Miley
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NMR studies of protein-small molecule and protein-peptide interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal
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Computational, biochemical, and NMR-driven structural studies on histone variant H2A.B
Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.
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André Gerrits bij Sleutelstad over Urban Studies
De Engelstalige bacheloropleiding Urban Studies ging dit jaar van start, maar wat houdt de opleiding precies in? André Gerrits, hoogleraar International Studies and Global Politics, was te gast bij Sleutelstad om te spreken over deze nieuwe opleiding.
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Targeting tumors using T-cell receptor gene transfer
Promotie
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Eerste universitaire bacheloropleiding Urban Studies in Nederland
De Universiteit Leiden heeft een nieuw interdisciplinair studieprogramma gelanceerd: Urban Studies. Studenten duiken in dit Engelstalige bachelorprogramma in hedendaagse en toekomstige stedenproblematiek. Het is de eerste studie waarvoor vijf faculteiten de handen ineenslaan.
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1 PhD Candidate to study transcription factor binding to chromatin at the single-molecule level
Wiskunde en Natuurwetenschappen, Leids Instituut voor Onderzoek in de Natuurkunde (LION)
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Security Studies krijgt bronzen predicaat EW Beste Studies 2023
De bachelor Security Studies heeft een bronzen medaille ontvangen in EW Beste studies 2023. Elk jaar selecteert EW Beste Studies topopleidingen.
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Chemical biology of glucosylceramide metabolism fundamental studies and applications for Gaucher disease
This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).
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Photothermal studies of single molecules and gold nanoparticles: vapor nanobubbles and conjugated polymers
Promotor: M.A.G.J. Orrit
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Electrochemical and surface studies of the effect of naphthalene-based additives on tin electrodeposition
Tin electrodeposition applications have rapidly evolved in the past 25 years.
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efficient membrane biophysical tool and its application in drug delivery studies
Promotor: A. Kros
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Mechanistic studies of the water oxidation reaction with molecular iron catalysts
In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.
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Diploma uitreiking BSc Security Studies: ‘Blijf nieuwsgierig’
Op woensdag 31 augustus 2022 vond de diploma-uitreiking plaats van de BSc Security Studies. De ceremonie werd geopend door programmadirecteur Daan Weggemans.
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Insights from modeling metabolism and amoeboid cell motility in the immune system
This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.
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CRISPR Cas-induced targeted mutagenesis with Agrobacterium mediated protein delivery
The RNA guided endonuclease based on the CRISPR/Cas system of Streptococcus pyogenus is a potent new tool for genome engineering in plants.
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Responding to environmental cues: the adaptive qualities of chromatin compaction proteins
Promotor: M. Ubbink, Co-Promotor: R. T. Dame
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The development of molecular tools for investigating NAD+ metabolism and signalling
Nicotinamide adenine dinucleotide (NAD+) is the substrate used for the introduction of the ubiquitous and highly dynamic PTM in which either one or multiple adenosine diphosphate ribose (ADPr) moieties are covalently attached to a nucleophilic side chain of an specific amino acid in the target protein…
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Lipidomics study in liver metabolic diseases
The ideas underlying this thesis are that lipidomics may improve the diagnosis of liver metabolic diseases, and can provide further insights into the underlying pathophysiology of these diseases.
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Temperature effects on genetic and physiological regulation of adaptive plasticity
Promotor: P.M. Brakefield
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CD8+ T-cells in atherosclerosis: mechanistic studies revealing a protective role in the plaque microenvironment
Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.
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Targeting for success: Mechanistic insights into microRNA-based gene therapy for Huntington disease
Promotie
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Bekijk de nieuwe alumnivideo van International Studies
Waar komen International Studies alumni terecht na hun afstuderen? Maak kennis met Guido, Paulien en Lennart. Zij deden alle drie de bachelor International Studies aan de Universiteit Leiden in Den Haag en zijn na hun studie in heel verschillende sectoren terechtgekomen.