956 zoekresultaten voor “multivariate analysis” in de Publieke website
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Statistical learning for complex data to enable precision medicine strategies
Explaining treatment response variability between and within patients can support treatment and dosing optimization, to improve treatment of individual patients.
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Contributions to the phylogeny of the haplolepideous mosses
The haplolepideous mosses (Dicranidae) comprise about 4000 species distributed over a wide range of habitats, with great gametophytic and sporophytic morphological variation. Their monophyly is well supported by the results of several molecular phylogenetic studies, which shed light on their relationships…
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Aspects of Record Linkage
Promotores: Prof.dr. J.N. Kok, Prof.dr. C.A. Mandemakers, Co-Promotor: G. Bloothooft
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Towards automated identification of metabolites using mass spectral trees
Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers
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Design and synthesis of metal-based chemotherapeutic agents for targeted DNA interactions or DNA repair pathway modulation
The research presented in this thesis explores the chemotherapeutic potential of metal-based compounds as chemotherapy agents, with an initial focus on the synthesis and DNA interaction studies of platinum and palladium compounds utilizing the [Pt(bapbpy)]2+ scaffold. The study identifies intercalation…
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Onderzoek
De programmagroep Leer- en Gedragsproblemen in het Onderwijs doet onderzoek naar stagnaties die kunnen optreden in de cognitieve ontwikkeling.
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Onderzoek
Het onderzoek van de afdeling Economie is ondergebracht bij meerdere facultaire programma's. Het onderzoek van de afdeling richt zich thans met name op sociaal-economische vraagstukken, rechtseconomie en fiscale economie.
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Identification and characterization of viral Xrn1-resistant RNAs
Several single-stranded RNA viruses make use of Xrn1-resistant RNAs in their 3’ untranslated regions of their genome RNAs in order to increase their pathogenicity.
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Applications of AdS/CFT to strongly correlated matter: from numerics to experiments
What physics controls the properties of quantum matter, such as how electrons flow inside high-temperature superconductors? This question has captivated the physics community and industry for decades, in part due to the great technological potential such materials have, but also because they have resisted…
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Quantum dot microcavity control of photon statistics
During my PhD research, I studied the photon statistics of light emitted by a microcavity that contains a single quantum dot (QD) on resonance.
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez
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Development of a Dynamic Substance Stock Model
Making a dynamic substance stock model in order to conduct scenario analyses and make forecasts.
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The structure of the cytochrome P450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography
Promotor: Prof.dr. M. Ubbink
- Thesis Lab: "The Source Course" (3 ECTS)
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Random walks and the contact process
Promotores: W. Th. F. den Hollander, M.O. Heydenreich
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Lasers, lenses and light curves: adaptive optics microscopy and peculiar transiting exoplanets
Promotores: Prof.dr. C.U. Keller, Prof.dr. H.C. Gerritsen
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Spectral signatures of breaking of ensemble equivalence
This thesis explores Breaking of Ensemble Equivalence (BEE) in random graph models by examining the spectral properties of adjacency matrices. The goal is to identify spectral characteristics that differentiate random graph ensembles, enhancing the understanding of complex network structures and beh…
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Imperfect information variants of combinatorial games
Combinatorial games are games for two competing players, moving in a turn-by-turn fashion, in which there is no chance nor hidden information. Chess, checkers and the simpler tic tac toe are well-known examples of this class of games, as well as game of go.
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Diversity in the globally intertwined giant barrel sponge species complex
This thesis describes the genetic and prokaryotic diversity of giant barrel sponges.
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Vervolgopleidingen
Wil je een volledige academische opleiding? Dan ga je na je bachelor door met een masteropleiding. Met een masterdiploma op zak heb je meer kans op een baan op academisch niveau. Na afronding krijg je de titel Master of Arts (MA).
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Principal algebraic actions of the discrete Heisenberg group
Promotor: Prof.dr. W.T.F. den Hollander
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Principles of Environmental Sciences
Principles of Environmental Sciences provides a comprehensive picture of the principles, concepts and methods that are applicable to problems originating from the interaction between the living and non-living environment and mankind. Both the analysis of such problems and the way solutions to environmental…
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Terpenoids and terpenoid indole alkaloids in Catharanthus roseus cell suspension cultures
Promotor: Prof.dr. R. Verpoorte, Co-Promotores: N.R. Mustafa, A.E. Schulte
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Real-time foresight: preparedness for dynamic innovation networks
Promotor: H.J. van den Herik, B.R. Katzy, Co-promotor: K. Sailer
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Roy Remme
Wiskunde en Natuurwetenschappen
r.p.remme@cml.leidenuniv.nl | +31 71 527 5610
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Nethmi Sewwandi Kankanamge Dona
Wiskunde en Natuurwetenschappen
n.s.kankanamge.dona@cml.leidenuniv.nl | +31 71 527 2727
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Ilios Willemars
Faculteit der Geesteswetenschappen
i.f.d.m.r.willemars@hum.leidenuniv.nl | +31 71 527 7160
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Lasse van den Dikkenberg
Faculteit Archeologie
l.van.den.dikkenberg@arch.leidenuniv.nl | +31 71 527 NNB
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Van data naar inzichten
Sociaal wetenschappelijk onderzoek leert ons om menselijk gedrag en maatschappelijke structuren te begrijpen. Deze worden bepaald door veel verschillende factoren. Dat maakt het onderzoek complex en vergroot de kans op onterechte conclusies. Het kiezen van de onderzoeksmethoden en analyses is dan ook…
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Publicaties
Publicaties die verschijnen in het kader van het onderzoeksproject Zelfredzaamheid en sociale bescherming over de levenscyclus.
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Intelligent Workflows for Automated Analysis of Mass Spectrometry- based Proteomics Data
Promotie
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‘Ik denk altijd: Wat zou voor mijzelf het beste gewerkt hebben?’
Beginnen met de waarom-vraag, zichzelf verplaatsen in haar studenten en structuur aanbrengen. Dat zijn drie manieren waarop milieuwetenschapper Ranran Wang haar cursus zo interessant en behapbaar mogelijk probeert te maken. Met succes: ze is genomineerd voor Science Teacher of the Year 2022.
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Celtypes in kaart gebracht van foetale nier
Nierfalen is een serieus probleem omdat nieren zichzelf niet kunnen regenereren na ernstige beschadiging. Een mogelijke oplossing bestaat uit het kunstmatig laten groeien van gezond nierweefsel. Daarvoor moeten wetenschappers eerst de ontwikkeling begrijpen tijdens de allereerste fase, in de foetus.…
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Shaping the European External Action Service and its post-Lisbon crisis management structures
This article 'Shaping the European External Action Service and its post-Lisbon crisis management structures: an assessment of the EU High Representatives’ political leadership' assesses the role, influence and core aspects of the EU High Representatives’ (HR/VPs) “political leadership” in the context…
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Cryptography from quantum uncertainty in the presence of quantum side information
Promotor: Ronald Cramer, Co-promotor: Serge Fehr
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Comparative biology of common and grey seals along the Dutch coast : stranding, disease, rehabilitation and conservation
Promotores: H.A. Udo De Haes, P.M. Brakefield
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Using insertional mutagenesis to identify breast cancer drivers and therapy resistance genes in mice
In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.
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Play by the rules? : coordination of EU sustainable development policies and the importance of the politico-legal context
There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…
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Establishing State Responsibility in the Absence of Effective Government
Op 16 juni 2020 verdedigde Andrea Varga haar proefschrift 'Establishing State Responsibility in the Absence of Effective Government'. Het promotieonderzoek is begeleid door promotoren prof. dr. N.J. Schrijver en prof. dr. F. Baetens (University of Oslo).
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Novel role of the AT-HOOK MOTIF NUCLEAR LOCALIZED 15 gene in Arabidopsis meristem activity and longevity
Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.
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Evolutionary Developmental Biology of Bitterling Fish
We developed the bitterling as a unique, well-studied model organism in the area of the evolutionary ecology of brood parasitism. The bitterling-mussel relationship, interspecific mussel host preference, and mussel gill structure are studied in detail, to help understand the developmental adaptation…
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Yiatrosofia yia ton Anthropo: Indigenous Knowledge of Medicinal, Aromatic and Cosmetic (MAC) Plants in the Utilisation of the Plural Medical
Promotor: Prof.dr. L.J. Slikkerveer
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Structural Properties of Single Server Queueing Systems: Efficient Methods via Lumping and Dynamic Programming
This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.
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Can traditional forest management protect and conserve ironwood (ulin) stands? An option and approach in East Kalimantan
Promotores: G.A. Persoon, H.H. de Iongh
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Attacks on hash functions and applications
Promotores: R. Cramer, A.K. Lenstra, Co-Promotor: B.M.M. de Weger
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Key innate immune components controlling intracellular infection
Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer
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Piecewise deterministic Markov processes: an analytic approach
Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans
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Astrophysical plasma modeling of the hot Universe: Advances and challenges in high-resolution X-ray spectroscopy
Hot astrophysical plasma is ubiquitous in the Universe, from comets in our Solar system to the largest scale structures -- the cosmic web filaments. These hot plasmas, with the temperature of a few millions of degrees, are often observed in the X-ray wavelength range.
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Automated machine learning for dynamic energy management using time-series data
Time-series forecasting through modelling sequences of temporally dependent observations has many industrial and scientific applications. While machine learning models have been widely used to create time-series forecasting models, creating efficient and performant time-series forecasting models is…
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Playing dice with the Universe
The ultimate goal of cosmologists is to find a cosmological model able to explain the current observational data.