In this thesis, time-lapse fluorescent microscopy plays a pivotal role in investigating functional materials within living cells as well as the migratory behaviour of neural progenitor cells.

This thesis focuses on the study of transient and variable radio sources in the universe.

In this Thesis, novel charge induction mechanisms of ionic liquids are treated, tested and experimented on complex oxides, in particular cuprates.

The studies described in this thesis deal with glycosidases, in particular alpha-galactosidases.

The thesis deals with the study of giant radio galaxies (GRGs), which are radio galaxies of megaparsec sizes.

The thesis focuses on synthesis strategies in oligosaccharide campaigns, and the influence of protecting groups.

This thesis combines field and laboratory studies to address some of the most pressing questions in the field of microplastic research.

This thesis has described novel synthetic methods to produce a variety of (glyco)peptides and their application in the study of various immunological processes.

This thesis discusses the physical and chemical processes than influence the composition of forming planets.

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

This thesis provides explicit expressions for the density functions of absolutely continuous invariant measures for general families of interval maps, that include random maps and infinite measure transformations, not necessarily number systems.

This thesis describes the role of pollution, specifically neonicotinoid insecticides, as an actor of the ongoing biodiversity decline.

Promotor: Prof.dr. A. Achucarro

This thesis applies data mining in commercial settings in the telecommunications industry.

Understanding the formation and evolution of planetary systems is one of the most fundamental challenges in astronomy. To directly image and study young exoplanets and the circumstellar disks they form from, dedicated high-contrast imaging instruments are built.

Promotores: Prof.dr. J. Aarts, Prof.dr. J.M. van Ruitenbeek

This thesis is about augmented reality (AR). AR is commonly considered a technology that integrates virtual images into a user’s view of the real world.

Childhood obesity is an increasing health issue. In the first part of this thesis comorbidities in children with obesity were studied, concerning the diagnostic process and dosing regimens.

This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.

This thesis presents pioneering work on the panchromatic emission of some of the most luminous galaxies in the early Universe: star forming galaxies and active galactic nuclei.

In this PhD-thesis several new and existing data science application are described that are particularly focused on applications for tax administrations.

Promotor: S.M. Verduyn Lunel, Co-Promotor: O.W. van Gaans

This Thesis focuses on the design and synthesis of ADP-ribosylated compounds that can be applied in biological studies.

Outflows are crucially important for the gas budget and evolution of luminous star-forming galaxies and AGNs, with observed mass outflow rates of the same order as the star formation rate. Greater star formation and black hole growth lead to more intense feedback and outflows, resulting in self-regulated…

The thesis is about the study of shell evolution of the Hydrocenidae of the genus Georissa. This thesis started with a general overview on the evolutionary process of animals due to ecological changes.

Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by limited treatment options and unfavorable clinical outcomes. Therefore, the research described in this thesis focused on the exploration of novel targeted therapies for TNBC.

This thesis investigates the contribution of quantum computers to machine learning, a field called Quantum Machine Learning. Quantum Machine Learning promises innovative perspectives and methods for solving complex problems in machine learning, leveraging the unique capabilities of quantum computers…

This thesis consists of three chapters, the first two of which concern division points of elements of the multiplicative group of a number field.

This thesis discusses the discovery potential of Intensity Frontier experiments.

This thesis presents the first synthetic peptides ADP-ribosylated on serine, threonine, tyrosine, arginine and cysteine.

The work described in this thesis focuses on the development of linear or cyclized peptide probes against protein N-methyltransferases to characterize their specific binding behavior, providing further binding details for inhibitory activity study.

In this thesis, the researcher developed a nanosystem based on the metallophilic Interaction between cyclometalated complexes.

The thesis explores how interstellar chemistry evolves as a function of time and changing physical architectures during the formation of stars.

The research described in this thesis focused on the preparation of S/N functionalized carbene ligands and their transition metal complexes, and the exploration of their application as electrocatalysts for proton reduction.

The thesis describes experimental steps towards reduction of friction on the macroscopic scale by scenarios of thermo- and superlubricity well-known on the nanoscale.

The thesis introduces three methods for high-dimensional prediction problems in the biomedical field. The methods make use of empirical and variational Bayes in the estimation.

In this thesis three different topics in number theory are studied.

In this thesis we study the moduli space of genus g curves, and the differential forms that occur naturally on this moduli space.

This thesis consists of five chapters on how to construct prediction sets for different types of data and models in a parametric or nonparametric Bayesian paradigm.

Lieke Kools heeft de Netspar PhD Thesis Award 2020 gewonnen met haar proefschrift “Wealth, health, and data collection”.

This thesis describes the evaluation of novel natural products with antibacterial activity enabled by total chemical synthesis.

The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.

In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.

This thesis investigates how galaxies form and what diversifies the evolutionary histories of galaxies.

Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…

The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

In the first part of this thesis we study the geometry of folding patterns.

In this thesis we have discussed several parameters that affect the electrochemical conversion of enviromentaly harmful molecules such as nitrates and carbon dioxide to more valuable and less deleterious compounds, in order to cast light onto the mechanism of the reaction to achieve an efficient and…

This thesis describes the implementation and on-sky demonstration of high-resolution integral-field spectroscopy for extreme adaptive optics systems that are used to find and characterize exoplanets.