Does the presence of Ring-necked parakeets negatively influence feeding and feeding behaviour of native bird species on artificial bird feeders and if so, what are possible solutions?

Op 23 juni 2020 verdedigde Santy Kouwagam haar proefschrift 'How lawyers win land conflicts for corporations: Legal Strategy and its influence on the Rule of Law in Indonesia'. Het promotieonderzoek is begeleid door promotoren prof.dr. A.W. Bedner en prof.dr. C.E. von Benda-Beckmann.

Sound is everywhere in the marine environment and hearing is therefore a very important for stimuli for fish. They use sound for orientation and communication, during migration, aggregation and spawning, but also for detection of prey and predators.

Lezing

Promotores: A.P. IJzerman, H.W.T. van Vlijmen

Promotor: B. van de Water

Promotor: Prof.dr. R. Verpoorte, Co-Promotor: Dr. Young Hae Choi

What were the Napoleonic Wars really about? This was the central problem posed to Europe by the partitions of Poland and the disintegration of the Holy Roman Empire, the collapse of the Westphalia system and the rising power of Russia. Adam Zamoyski will give this lecture on account of his new book…

The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…

In this thesis population pharmacokinetic and physiologically-based pharmacokinetic (PBPK) approaches were applied to investigate the influence of glomerular filtration (GF) and active tubular secretion (ATS) on renal clearance in children.

Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.

This thesis focusses on the temperature structure in protoplanetary disks. The relation between structures seen in the dust and gas-phase molecules is investigated.

Stimulerende drugs als khat en cocaïne hebben negatieve impact op dagelijkse handelingen als autorijden, werk of sociaal gedrag. Dat komt door beschadiging van controlefuncties in de hersenen. Psycholoog Manuel Ruiz draagt bij aan beter begrip en behandeling van drugsmisbruik. De Spanjaard Ruiz promoveert…

Josien de Klerk en Tennessee Miller onderzochten de interactie tussen de ziekte- en herstelervaringen van studenten en de academische werkcultuur in deze context.

De auteurs zoeken en beoordelen systematisch relevante definities van Security by Design (SbD) in vergelijking met Privacy by Design (PbD).

In dit artikel onderzochten Annemiek de Looze en Eefje Cuppen empirisch of en hoe sociaal conflict leidt tot institutionele verandering.

Op 26 juni 2019 verdedigde Lisa Louwerse haar proefschrift 'The EU’s Conceptualisation of the Rule of Law in its External Relations: Case Studies on Development Cooperation and Enlargement'. Het promotieonderzoek is begeleid door promotor prof. mr. C.A.P. Hillion.

Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…

Promotie

Promotie

This thesis describes the design, characterization and application of dextran based crosslinked network.

As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.

It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.

Dit proefschrift gaat over de invloed van inductieprogramma’s op het welbevinden en de professionele ontwikkeling van beginnende docenten, en welke specifieke kenmerken van inductieprogramma’s daarvoor belangrijk zijn. Hiernaar is onderzoek gedaan met een interviewstudie en een grootschalige vragenl…

Promotor: Prof.dr. M. Ubbink

Promoter: Ed F. Deprettere, Co-promoter: Todor P. Stefanov

In deze studie wordt verslag gedaan van een onderzoek naar de ontwikkeling van de praktijkkennis bij elf docenten Nederlands. Zij ontwikkelden en implementeerden concept-contextrijk onderwijs met behulp van actieonderzoek.

This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.

What are trait-trait relationships in wetlands? To what extent the so-called leaf economics traits deviate from terrestrial ecosystems? How traits specific to wetland plant relate to plant strategies? What’s the relationship between wetland plant traits to the ecosystem functioning (e.g. productivity,…

Promotors: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Prof.dr.ir. H.H. de Iongh

Onze gemiddelde leeftijd gaat omhoog en de behoefte naar goede gezondheidszorg wordt steeds groter. Nieuwe medicijnen moeten op de markt komen maar kosten voor de ontwikkeling daarvan moeten omlaag. Tijdens het Medical Delta café op 8 oktober presenteren o.a. dr. Leo Price, dr. Jan de Sonneville en…

The intradermal administration route is attractive for vaccine delivery, because of the highly populated antigen-presenting cells in the skin. However, the skin’s main physical barrier, the stratum corneum, prevents vaccines from entering the skin.

Announcement of a new publication by Janneke Verheijen, lecturer at the Institute of Cultural Anthropology and Development Sociology.

Debat

Onderzoek naar representatieve bureaucratie heeft vaak de positieve prestatie-effecten bevestigd van bureaucratieën die de demografische kenmerken van hun cliënten weerspiegelen. Er is echter weinig bekend over de onderliggende mechanismen op individueel niveau die tot deze resultaten leiden.

The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.

Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Co-promotor: H.H. de Iongh

The ministry of education (OC en W) has generously decided to subsidize the Encompass program with a grant of 1 million euro’s for the years 2012-2016.

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.

Promotor: E. Bouwman, Co-promotor: S. Bonnet

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

Dit onderzoek richt zich op hoe de voedselconsumptie en -verspilling van huishoudens tijdens COVID-19 werd aangepast aan de levensstijl.

This thesis consists of two subjects, that are both a consequence of radiation pressure.

Deelproject van

In een café een drankje drinken en tegelijk wat opsteken over sterrenkunde: dat is Astronomy on Tap. Op maandag 27 maart vindt de eerste editie plaats in Leiden.

In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.

The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.

Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.